Search Results - "Paolo, Antonello Di"

Pharmacokinetic drug-drug interaction and their implication in clinical management by Palleria, Caterina, Di Paolo, Antonello, Giofrè, Chiara, Caglioti, Chiara, Leuzzi, Giacomo, Siniscalchi, Antonio, De Sarro, Giovambattista, Gallelli, Luca

“…Drug-drug interactions (DDIs) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly-therapy, with…”
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Oral Gentamicin Gut Decontamination for Prevention of KPC-Producing Klebsiella pneumoniae Infections: Relevance of Concomitant Systemic Antibiotic Therapy by TASCINI, Carlo, SBRANA, Francesco, LEWIS, Russell, ROSSOLINI, Gian Maria, MENICHETTI, Francesco, FLAMMINI, Sarah, TAGLIAFERRI, Enrico, ARENA, Fabio, LEONILDI, Alessandro, CIULLO, Ilaria, AMADORI, Francesco, DI PAOLO, Antonello, RIPOLI, Andrea

“…Gut colonization represents the main source for KPC-producing Klebsiella pneumoniae (KPC-Kp) epidemic dissemination. Oral gentamicin, 80 mg four times daily,…”
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Pharmacogenetics of BCR/ABL Inhibitors in Chronic Myeloid Leukemia by Polillo, Marialuisa, Galimberti, Sara, Baratè, Claudia, Petrini, Mario, Danesi, Romano, Di Paolo, Antonello

“…Chronic myeloid leukemia was the first haematological neoplasia that benefited from a targeted therapy with imatinib nearly 15 years ago. Since then, several…”
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5-Fluorouracil Pharmacokinetics Predicts Disease-free Survival in Patients Administered Adjuvant Chemotherapy for Colorectal Cancer by Di Paolo, Antonello, Lencioni, Monica, Amatori, Federica, Di Donato, Samantha, Bocci, Guido, Orlandini, Cinzia, Lastella, Marianna, Federici, Francesca, Iannopollo, Mauro, Falcone, Alfredo, Ricci, Sergio, Del Tacca, Mario, Danesi, Romano

“…Purpose: To evaluate 5-fluorouracil (5-FU) and 5-fluoro-5,6-dihydrouracil (5-FDHU) pharmacokinetics and disease-free survival (DFS) in colorectal cancer…”
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The pharmacological bases of the antiangiogenic activity of paclitaxel by Bocci, Guido, Di Paolo, Antonello, Danesi, Romano

“…In the mid 1990s, researchers began to investigate the antiangiogenic activity of paclitaxel as a possible additional mechanism contributing to its…”
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Personalized Medicine of Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacogenetics, Therapeutic Drug Monitoring, and Beyond by Di Paolo, Antonello, Luci, Giacomo

“…The pharmacotherapy of inflammatory bowel diseases (Crohn's disease and ulcerative colitis) has experienced significant progress with the advent of monoclonal…”
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Personalized medicine in Europe: not yet personal enough? by Di Paolo, Antonello, Sarkozy, François, Ryll, Bettina, Siebert, Uwe

“…Personalized medicine has the potential to allow patients to receive drugs specific to their individual disease, and to increase the efficiency of the…”
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Interactions between Food and Drugs, and Nutritional Status in Renal Patients: A Narrative Review by D'Alessandro, Claudia, Benedetti, Alessia, Di Paolo, Antonello, Giannese, Domenico, Cupisti, Adamasco

“…Drugs and food interact mutually: drugs may affect the nutritional status of the body, acting on senses, appetite, resting energy expenditure, and food intake;…”
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The CoV-2 outbreak: how hematologists could help to fight Covid-19 by Galimberti, Sara, Baldini, Chiara, Baratè, Claudia, Ricci, Federica, Balducci, Serena, Grassi, Susanna, Ferro, Francesco, Buda, Gabriele, Benedetti, Edoardo, Fazzi, Rita, Baglietto, Laura, Lucenteforte, Ersilia, Di Paolo, Antonello, Petrini, Mario

“…[Display omitted] COVID-19 is a medical emergency, with 20 % of patients presenting with severe clinical manifestations. From the pathogenetic point of view,…”
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Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study by Scatena, Cristian, Roncella, Manuela, Di Paolo, Antonello, Aretini, Paolo, Menicagli, Michele, Fanelli, Giovanni, Marini, Carolina, Mazzanti, Chiara Maria, Ghilli, Matteo, Sotgia, Federica, Lisanti, Michael P, Naccarato, Antonio Giuseppe

“…Cancer stem cells (CSCs) have been implicated in tumor initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast cancers…”
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Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment by Arrigoni, Elena, Del Re, Marzia, Galimberti, Sara, Restante, Giuliana, Rofi, Eleonora, Crucitta, Stefania, Baratè, Claudia, Petrini, Mario, Danesi, Romano, Di Paolo, Antonello

“…Nowadays, more than 90% of patients affected by chronic myeloid leukemia (CML) survive with a good quality of life, thanks to the clinical efficacy of tyrosine…”
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Concise Review: Resistance to Tyrosine Kinase Inhibitors in Non‐Small Cell Lung Cancer: The Role of Cancer Stem Cells by Del Re, Marzia, Arrigoni, Elena, Restante, Giuliana, Passaro, Antonio, Rofi, Eleonora, Crucitta, Stefania, De Marinis, Filippo, Di Paolo, Antonello, Danesi, Romano

“…Among the potential mechanisms involved in resistance to tyrosine kinase inhibitors (TKIs) in non‐small cell lung cancer, the manifestation of stem‐like…”
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Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins by Arrigoni, Elena, Del Re, Marzia, Fidilio, Leonardo, Fogli, Stefano, Danesi, Romano, Di Paolo, Antonello

“…In the era of precision medicine, more attention is paid to the search for predictive markers of treatment efficacy and tolerability. Statins are one of the…”
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Tyrosine Kinase Inhibitors Play an Antiviral Action in Patients Affected by Chronic Myeloid Leukemia: A Possible Model Supporting Their Use in the Fight Against SARS-CoV-2 by Galimberti, Sara, Petrini, Mario, Baratè, Claudia, Ricci, Federica, Balducci, Serena, Grassi, Susanna, Guerrini, Francesca, Ciabatti, Elena, Mechelli, Sandra, Di Paolo, Antonello, Baldini, Chiara, Baglietto, Laura, Macera, Lisa, Spezia, Pietro Giorgio, Maggi, Fabrizio

“…SARS-CoV-2 is the viral agent responsible for the pandemic that in the first months of 2020 caused about 400,000 deaths. Among compounds proposed to fight the…”
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Pharmacokinetics of Non-β-Lactam β-Lactamase Inhibitors by Luci, Giacomo, Mattioli, Francesca, Falcone, Marco, Di Paolo, Antonello

“…The growing emergence of drug-resistant bacterial strains is an issue to treat severe infections, and many efforts have identified new pharmacological agents…”
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Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients by Cucchiara, Federico, Luci, Giacomo, Giannini, Noemi, Giorgi, Filippo Sean, Orlandi, Paola, Banchi, Marta, Di Paolo, Antonello, Pasqualetti, Francesco, Danesi, Romano, Bocci, Guido

“…Glioblastoma multiforme (GBM) is an aggressive brain tumor, often occurring with seizures managed with antiepileptic drugs, such as levetiracetam (LEV). This…”
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Precision Medicine in Lymphoma by Innovative Instrumental Platforms by Di Paolo, Antonello, Arrigoni, Elena, Luci, Giacomo, Cucchiara, Federico, Danesi, Romano, Galimberti, Sara

“…In recent years, many efforts have been addressed to the growing field of precision medicine in order to offer individual treatments to every patient on the…”
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Tissue Penetration of Antimicrobials in Intensive Care Unit Patients: A Systematic Review—Part I by Finazzi, Stefano, Luci, Giacomo, Olivieri, Carlo, Langer, Martin, Mandelli, Giulia, Corona, Alberto, Viaggi, Bruno, Di Paolo, Antonello

“…The challenging severity of some infections, especially in critically ill patients, makes the diffusion of antimicrobial drugs within tissues one of the…”
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Appropriateness of repetitive therapeutic drug monitoring and laboratory turnaround time by Sarli, Valentina, Ciofi, Laura, Lastella, Marianna, Muscatello, Beatrice, Pisaturo, Fioravante, Paolilli, Ombretta, Luci, Giacomo, Cucchiara, Federico, Pellegrini, Giovanni, Bocci, Guido, Danesi, Romano, Di Paolo, Antonello

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Population Pharmacokinetics of Intravenous Acyclovir in Oncologic Pediatric Patients by Maximova, Natalia, Nisticò, Daniela, Luci, Giacomo, Simeone, Roberto, Piscianz, Elisa, Segat, Ludovica, Barbi, Egidio, Di Paolo, Antonello

“…Acyclovir represents the first-line prophylaxis and therapy for herpes virus infections. However, its pharmacokinetics in children exposes them to the risk of…”
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