Search Results - "Paolino, Donatella"
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Mucosal Applications of Poloxamer 407-Based Hydrogels: An Overview
Published in Pharmaceutics (12-09-2018)“…Poloxamer 407, also known by the trademark Pluronic F127, is a water-soluble, non-ionic triblock copolymer that is made up of a hydrophobic residue of…”
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Mathematical Modeling of Release Kinetics from Supramolecular Drug Delivery Systems
Published in Pharmaceutics (21-03-2019)“…Embedding of active substances in supramolecular systems has as the main goal to ensure the controlled release of the active ingredients. Whatever the final…”
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3
Safety of Nanoparticles in Medicine
Published in Current drug targets (01-01-2015)“…Nanomedicine involves the use of nanoparticles for therapeutic and diagnostic purposes. During the past two decades, a growing number of nanomedicines have…”
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Influence of Various Model Compounds on the Rheological Properties of Zein-Based Gels
Published in Molecules (Basel, Switzerland) (11-07-2020)“…The controlled release of a compound entrapped in a biocompatible formulation is a sought-after goal in modern pharmaceutical technology. Zein is a hydrophobic…”
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Mathematical Models as Tools to Predict the Release Kinetic of Fluorescein from Lyotropic Colloidal Liquid Crystals
Published in Materials (26-02-2019)“…In this study, we investigated the release kinetic of fluorescein from colloidal liquid crystals made from monoglyceride and different non-ionic surfactants…”
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Perspective use of bio-adhesive liquid crystals as ophthalmic drug delivery systems
Published in Scientific reports (27-09-2023)“…The success of many drugs in ophthalmic treatments is hindered by their physico-chemical properties and the limited precorneal retention time. Here, lyotropic…”
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Sclareol-loaded hyaluronan-coated PLGA nanoparticles: Physico-chemical properties and in vitro anticancer features
Published in International journal of biological macromolecules (01-07-2019)“…Sclareol (labd‑14‑ene‑8,13‑diol), a phytochemical compound belonging to labdane-type diterpenes, has recently attracted noteworthy attention because of its…”
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Anti-inflammatory activity of novel ammonium glycyrrhizinate/niosomes delivery system: Human and murine models
Published in Journal of controlled release (28-11-2012)“…Today there is a very great deal of interest among members of the global natural products community in investigating new plant constituents. Recent studies…”
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In Situ Swelling Formulation of Glycerol-Monooleate-Derived Lyotropic Liquid Crystals Proposed for Local Vaginal Application
Published in Molecules (Basel, Switzerland) (23-09-2022)“…Hydrogels have been extensively investigated to identify innovative formulations that can fulfill all the necessary purposes to improve local vaginal therapy…”
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Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma
Published in Scientific reports (01-12-2015)“…The encapsulation of miR-34a into chitosan/PLGA nanoparticles in order to obtain nanoplexes useful for the modulation of the biopharmaceutical features of the…”
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11
The Rheolaser Master™ and Kinexus Rotational Rheometer ® to Evaluate the Influence of Topical Drug Delivery Systems on Rheological Features of Topical Poloxamer Gel
Published in Molecules (Basel, Switzerland) (23-04-2020)“…Poloxamer 407 copolymer is a versatile and widely used thermo-reversible material. Its use has many advantages, such as bio-adhesion, enhanced solubilization…”
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12
Cardiac Stem Cell-Loaded Delivery Systems: A New Challenge for Myocardial Tissue Regeneration
Published in International journal of molecular sciences (18-10-2020)“…Cardiovascular disease (CVD) remains the leading cause of death in Western countries. Post-myocardial infarction heart failure can be considered a degenerative…”
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Author Correction: Perspective use of bio-adhesive liquid crystals as ophthalmic drug delivery systems
Published in Scientific reports (18-12-2023)Get full text
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14
Essential Oils-Loaded Polymer Particles: Preparation, Characterization and Antimicrobial Property
Published in Polymers (09-06-2019)“…In the last few years, essential oils (EOs) derived from plants have aroused great interest due to their well-known antimicrobial activity. Unfortunately, they…”
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Rutin-Loaded Solid Lipid Nanoparticles: Characterization and In Vitro Evaluation
Published in Molecules (Basel, Switzerland) (16-02-2021)“…This study was aimed at preparing and characterizing solid lipid nanoparticles loading rutin (RT-SLNs) for the treatment of oxidative stress-induced diseases…”
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Paclitaxel-loaded sodium deoxycholate-stabilized zein nanoparticles: characterization and in vitro cytotoxicity
Published in Heliyon (01-09-2019)“…Paclitaxel (PTX) is one of the most successful antineoplastic drugs and is widely used for the treatment of many forms of advanced and refractory cancer…”
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Reflectance spectroscopy: a non-invasive strategy to explore skin reactions to topical products
Published in Frontiers in chemistry (18-06-2024)“…Reflectance spectroscopy has emerged as a powerful analytical technique in the field of dermatology, offering a non-invasive strategy to assess several…”
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Influence of Materials Properties on Bio-Physical Features and Effectiveness of 3D-Scaffolds for Periodontal Regeneration
Published in Molecules (Basel, Switzerland) (15-03-2021)“…Periodontal diseases are multifactorial disorders, mainly due to severe infections and inflammation which affect the tissues (i.e., gum and dental bone) that…”
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Interaction between PEG lipid and DSPE/DSPC phospholipids: An insight of PEGylation degree and kinetics of de-PEGylation
Published in Colloids and surfaces, B, Biointerfaces (01-07-2017)“…[Display omitted] •Effect of polyethylene glycol (PEG) content for the PEGylation of liposomes.•Kinetic of PEGylation and de-PEGylation of…”
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Late relapse after CAR-T cell therapy for adult patients with hematologic malignancies: A definite evidence from systematic review and meta-analysis on individual data
Published in Pharmacological research (01-04-2023)“…Chimeric Antigen Receptor (CAR)-modified T lymphocytes represent one of the most innovative and promising approaches to treating hematologic malignancies…”
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