Search Results - "Paolini, Francesca"
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1
Going “beyond the mean” in analyzing immigrant health disparities
Published in Demographic research (01-07-2022)“…On arrival, immigrants are on average healthier than Italian natives, but their health advantage tends to dissipate over time. This constitutes a relevant…”
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2
Papillomavirus E5: the smallest oncoprotein with many functions
Published in Molecular cancer (11-11-2011)“…Papillomaviruses (PVs) are established agents of human and animal cancers. They infect cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are…”
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3
Different immunogens and prime-boost vaccination strategies affect the efficacy of recombinant candidate vaccines against pathogenic orthopoxviruses
Published in Virology journal (07-11-2024)“…Abstract Although not as lethal as variola virus (VARV), the cause of smallpox, monkeypox virus (MPXV) represents a threat to public health, with important…”
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4
Bioproduction of a Therapeutic Vaccine Against Human Papillomavirus in Tomato Hairy Root Cultures
Published in Frontiers in plant science (11-04-2019)“…Human papillomavirus (HPV) tumor disease is a critical public health problem worldwide, especially in the developing countries. The recognized pathogenic…”
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5
Construction of a recombinant avipoxvirus expressing the env gene of Zika virus as a novel putative preventive vaccine
Published in Virology journal (04-03-2021)“…Zika virus (ZIKV) has been declared a public health emergency that requires development of an effective vaccine, as it might represent an international threat…”
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6
Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition
Published in Cell death & disease (05-01-2023)“…PARP inhibitors (PARPi) have changed the treatment paradigm of high-grade serous ovarian cancer (HG-SOC). However, the impact of this class of inhibitors in…”
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7
The landscape of circulating tumor HPV DNA and TTMV-HPVDNA for surveillance of HPV-oropharyngeal carcinoma: systematic review and meta-analysis
Published in Journal of experimental & clinical cancer research (03-08-2024)“…Human papilloma virus (HPV) related cancers of the oropharynx are rapidly increasing in incidence and may soon represent the majority of all head and neck…”
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Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors
Published in Journal of experimental & clinical cancer research (23-01-2021)“…The oncogenic activity of the high risk human papillomavirus type 16 (HPV16) is fully dependent on the E6 and E7 viral oncoproteins produced during viral…”
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9
Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer
Published in Journal of immunology research (01-01-2019)“…Mollusk hemocyanins have been used for decades in immunological and clinical applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants…”
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10
Modifying Anthocyanins Biosynthesis in Tomato Hairy Roots: A Test Bed for Plant Resistance to Ionizing Radiation and Antioxidant Properties in Space
Published in Frontiers in plant science (24-02-2022)“…Gene expression manipulation of specific metabolic pathways can be used to obtain bioaccumulation of valuable molecules and desired quality traits in plants. A…”
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11
Beta HPV Type 15 Can Interfere With NF-κB Activity and Apoptosis in Human Keratinocytes
Published in Frontiers in cellular and infection microbiology (18-03-2020)“…E7 protein from cutaneous as well as mucosal HPV types can alter NF-κB activity. Conflicting literature data show a HPV-induced up- or down-regulation of the…”
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12
The Effectiveness of Therapeutic Vaccines for the Treatment of Cervical Intraepithelial Neoplasia 3: A Systematic Review and Meta-Analysis
Published in Vaccines (Basel) (19-09-2022)“…Cervical cancer (CC) is a disease that affects many women worldwide, especially in low-income countries. The human papilloma virus (HPV) is the main causative…”
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13
In vivo antitumor effect of an intracellular single‐chain antibody fragment against the E7 oncoprotein of human papillomavirus 16
Published in International journal of cancer (01-06-2014)“…Human papillomavirus (HPV)‐associated tumors still represent an urgent problem of public health in spite of the efficacy of the prophylactic HPV vaccines…”
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14
PBMCs are additional sites of productive infection of bovine papillomavirus type 2
Published in Journal of general virology (01-08-2011)“…Bovine papillomavirus type 2 (BPV-2) is an oncogenic virus infecting both epithelial and mesenchymal cells. Its life cycle, similar to other papillomaviruses…”
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15
Multi-omic approach identifies a transcriptional network coupling innate immune response to proliferation in the blood of COVID-19 cancer patients
Published in Cell death & disease (29-10-2021)“…Clinical outcomes of COVID-19 patients are worsened by the presence of co-morbidities, especially cancer leading to elevated mortality rates. SARS-CoV-2…”
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hMENA isoforms regulate cancer intrinsic type I IFN signaling and extrinsic mechanisms of resistance to immune checkpoint blockade in NSCLC
Published in Journal for immunotherapy of cancer (01-08-2023)“…Background Understanding how cancer signaling pathways promote an immunosuppressive program which sustains acquired or primary resistance to immune checkpoint…”
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17
HPV 16 E5 oncoprotein is expressed in early stage carcinogenesis and can be a target of immunotherapy
Published in Human vaccines & immunotherapeutics (01-02-2017)“…HPV16 persistent infection is a well-known condition that precedes human cancer development. High risk HPV E5 proteins cooperate with E6/E7 oncogenes to…”
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18
Designing a novel tomato ideotype for future cultivation in space manned missions
Published in Frontiers in astronomy and space sciences (06-01-2023)“…Introduction: Methods for production of fresh, health food are needed in view of long-term, deep-space manned missions. To this end, crops tailored for better…”
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Deconvolution of malignant pleural effusions immune landscape unravels a novel macrophage signature associated with worse clinical outcome in lung adenocarcinoma patients
Published in Journal for immunotherapy of cancer (01-05-2022)“…BackgroundImmune checkpoint inhibitors are still unable to provide clinical benefit to the large majority of non-small cell lung cancer (NSCLC) patients. A…”
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ePCL Electrospun Microfibrous Layers for Immune Assays: Sensitive ELISA for the Detection of Serum Antibodies Against HPV16 E7 Oncoprotein
Published in ACS omega (06-04-2021)“…Human papillomavirus (HPV) type 16 is the etiologic agent of more than 50% anal/cervical cancers and about 20% oropharyngeal cancers. HPV16 E6 and E7 oncogenes…”
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