Search Results - "Paoli, Eric"

Acoustically-active microbubbles conjugated to liposomes: Characterization of a proposed drug delivery vehicle by Kheirolomoom, Azadeh, Dayton, Paul A., Lum, Aaron F.H., Little, Erika, Paoli, Eric E., Zheng, Hairong, Ferrara, Katherine W.

“…A new acoustically-active delivery vehicle was developed by conjugating liposomes and microbubbles, using the high affinity interaction between avidin and…”
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Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus by Gilmore, Sarah A, Tam, Danny, Cheung, Tara L, Snyder, Chelsea, Farand, Julie, Dick, Ryan, Matles, Mike, Feng, Joy Y, Ramirez, Ricardo, Li, Li, Yu, Helen, Xu, Yili, Barnes, Dwight, Czerwieniec, Gregg, Brendza, Katherine M, Appleby, Todd C, Birkus, Gabriel, Willkom, Madeleine, Kobayashi, Tetsuya, Paoli, Eric, Labelle, Marc, Boesen, Thomas, Tay, Chin H, Delaney, 4th, William E, Notte, Gregory T, Schmitz, Uli, Feierbach, Becket

“…Chronic hepatitis B (CHB) is a global health care challenge and a major cause of liver disease. To find new therapeutic avenues with a potential to…”
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Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus by Sarah A Gilmore, Danny Tam, Tara L Cheung, Chelsea Snyder, Julie Farand, Ryan Dick, Mike Matles, Joy Y Feng, Ricardo Ramirez, Li Li, Helen Yu, Yili Xu, Dwight Barnes, Gregg Czerwieniec, Katherine M Brendza, Todd C Appleby, Gabriel Birkus, Madeleine Willkom, Tetsuya Kobayashi, Eric Paoli, Marc Labelle, Thomas Boesen, Chin H Tay, William E Delaney, Gregory T Notte, Uli Schmitz, Becket Feierbach

“…Chronic hepatitis B (CHB) is a global health care challenge and a major cause of liver disease. To find new therapeutic avenues with a potential to…”
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Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes by Paoli, Eric E., Ingham, Elizabeth S., Zhang, Hua, Mahakian, Lisa M., Fite, Brett Z., Gagnon, M. Karen, Tam, Sarah, Kheirolomoom, Azadeh, Cardiff, Robert D., Ferrara, Katherine W.

“…Advancements in liposomal drug delivery have produced long circulating and very stable drug formulations. These formulations minimize systemic exposure;…”
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A Radio-Frequency Coupling Network for Heating of Citrate-Coated Gold Nanoparticles for Cancer Therapy: Design and Analysis by Kruse, Dustin E., Stephens, Douglas N., Lindfors, Heather A., Ingham, Elizabeth S., Paoli, Eric E., Ferrara, Katherine W.

“…Gold nanoparticles (GNPs) are nontoxic, can be functionalized with ligands, and preferentially accumulate in tumors. We have developed a 13.56-MHz…”
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Copper−Doxorubicin as a Nanoparticle Cargo Retains Efficacy with Minimal Toxicity by Kheirolomoom, Azadeh, Mahakian, Lisa M, Lai, Chun-Yen, Lindfors, Heather A, Seo, Jai Woong, Paoli, Eric E, Watson, Katherine D, Haynam, Eric M, Ingham, Elizabeth S, Xing, Li, Cheng, R. Holland, Borowsky, Alexander D, Cardiff, Robert D, Ferrara, Katherine W

“…Repeated administration of chemotherapeutics is typically required for the effective treatment of highly aggressive tumors and often results in systemic…”
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Spatial and Temporal-Controlled Tissue Heating on a Modified Clinical Ultrasound Scanner for Generating Mild Hyperthermia in Tumors by Kruse, Dustin E., Lai, Chun-Yen, Stephens, Douglas N., Sutcliffe, Patrick, Paoli, Eric E., Barnes, Stephen H., Ferrara, Katherine W.

“…A new system is presented for generating controlled tissue heating with a clinical ultrasound scanner, and initial in vitro and in vivo results are presented…”
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Maximizing Parameters for Tissue Ablation by Using an Internally Cooled Electrode by MCGAHAN, John P, LOH, Shaun, BOSCHINI, Fernando J, PAOLI, Eric E, BROCK, John M, MONSKY, Wayne L, LI, Chin-Shang

“…To compare an algorithm of gradually ramped-up power to a full-power-level technique to determine which technical parameters maximized tissue coagulation by…”
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A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model by Yant, Stephen R., Mulato, Andrew, Hansen, Derek, Tse, Winston C., Niedziela-Majka, Anita, Zhang, Jennifer R., Stepan, George J., Jin, Debi, Wong, Melanie H., Perreira, Jill M., Singer, Eric, Papalia, Giuseppe A., Hu, Eric Y., Zheng, Jim, Lu, Bing, Schroeder, Scott D., Chou, Kevin, Ahmadyar, Shekeba, Liclican, Albert, Yu, Helen, Novikov, Nikolai, Paoli, Eric, Gonik, Daniel, Ram, Renee R., Hung, Magdeleine, McDougall, William M., Brass, Abraham L., Sundquist, Wesley I., Cihlar, Tomas, Link, John O.

“…People living with HIV (PLWH) have expressed concern about the life-long burden and stigma associated with taking pills daily and can experience medication…”
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Species-Specific Urothelial Toxicity With an Anti-HIV Noncatalytic Site Integrase Inhibitor (NCINI) Is Related to Unusual pH-Dependent Physicochemical Changes by Roberts, Ruth A, Campbell, Richard A, Sikakana, Phumzile, Sadler, Claire, Osier, Mark, Xu, Yili, Feng, Joy Y, Mitchell, Michael, Sakowicz, Roman, Chester, Anne, Paoli, Eric, Wang, Jianhong, Burns-Naas, Leigh Ann

“…Abstract GS-9695 and GS-9822 are next-generation noncatalytic site integrase inhibitors (NCINIs) with significantly improved potency against human…”
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Galaxy Is a Suitable Bioinformatics Platform for the Molecular Diagnosis of Human Genetic Disorders Using High-Throughput Sequencing Data Analysis: Five Years of Experience in a Clinical Laboratory by Chappell, Kenneth, Francou, Bruno, Habib, Christophe, Huby, Thomas, Leoni, Marco, Cottin, Aurélien, Nadal, Florian, Adnet, Eric, Paoli, Eric, Oliveira, Christophe, Verstuyft, Céline, Davit-Spraul, Anne, Gaignard, Pauline, Lebigot, Elise, Duclos-Vallee, Jean-Charles, Young, Jacques, Kamenicky, Peter, Adams, David, Echaniz-Laguna, Andoni, Gonzales, Emmanuel, Bouvattier, Claire, Linglart, Agnes, Picard, Véronique, Bergoin, Emilie, Jacquemin, Emmanuel, Guiochon-Mantel, Anne, Proust, Alexis, Bouligand, Jérôme

“…To date, the usage of Galaxy, an open-source bioinformatics platform, has been reported primarily in research. We report 5 years' experience (2015 to 2020)…”
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Maximizing Parameters for Tissue Ablation by Using an Internally Cooled Electrode1 by McGahan, John P., Loh, Shaun, Boschini, Fernando J., Paoli, Eric E., Brock, John M., Monsky, Wayne L., Li, Chin-Shang

“…Our results showed that both use of gradual increase of power levels and restarting the generator after the equipment reached initial impedance level will…”
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Spatial and Temporal-Controlled Tissue Heating on a Modified Clinical Ultrasound Scanner for Generating Mild Hyperthermia in Tumors: TBME LETTERS AND REGULAR PAPERS SPECIAL ISSUE ON THERAPEUTIC ULTRASOUND by KRUSE, Dustin E, LAI, Chun-Yen, STEPHENS, Douglas N, SUTCLIFFE, Patrick, PAOLI, Eric E, BARNES, Stephen H, FERRARA, Katherine W

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The Optimization of Liposomes for Image Guided Drug-Delivery by Paoli, Eric Edward

“…Liposomes are spherical vesicles composed of phospholipids that arise spontaneously in aqueous environments. Such vesicles are composed of the same material…”
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