Search Results - "Paola Perini"

Therapy of Pediatric-Onset Multiple Sclerosis: State of the Art, Challenges, and Opportunities by Margoni, Monica, Rinaldi, Francesca, Perini, Paola, Gallo, Paolo

“…Treatment of pediatric-onset multiple sclerosis (POMS) has been tailored after observational studies and data obtained from clinical trials in adult-onset…”
Get full text

A 3-year magnetic resonance imaging study of cortical lesions in relapse-onset multiple sclerosis by Calabrese, Massimiliano, Rocca, Maria A., Atzori, Matteo, Mattisi, Irene, Favaretto, Alice, Perini, Paola, Gallo, Paolo, Filippi, Massimo

“…Objective We assessed the occurrence, extent, and frequency of formation of cortical lesions (CLs) in patients with relapsing‐remitting (RR) and secondary…”
Get full text

The changing clinical course of multiple sclerosis: A matter of gray matter by Calabrese, Massimiliano, Romualdi, Chiara, Poretto, Valentina, Favaretto, Alice, Morra, Aldo, Rinaldi, Francesca, Perini, Paola, Gallo, Paolo

“…Objective Clinical and neuroimaging parameters predictive of the changing clinical course of multiple sclerosis (MS) from relapsing–remitting to secondary…”
Get full text

Trans-synaptic degeneration in the optic pathway. A study in clinically isolated syndrome and early relapsing-remitting multiple sclerosis with or without optic neuritis by Puthenparampil, Marco, Federle, Lisa, Poggiali, Davide, Miante, Silvia, Signori, Alessio, Pilotto, Elisabetta, Rinaldi, Francesca, Perini, Paola, Sormani, Maria Pia, Midena, Edoardo, Gallo, Paolo

“…Increasing evidence suggest that neuronal damage is an early and diffuse feature of Multiple Sclerosis (MS) pathology. Analysis of the optic pathway may help…”
Get full text

Hyper-reflective foci changes in RRMS under natalizumab therapy by Puthenparampil, Marco, Basili, Elisa, Ponzano, Marta, Mauceri, Valentina Annamaria, Miscioscia, Alessandro, Pilotto, Elisabetta, Perini, Paola, Rinaldi, Francesca, Bovis, Francesca, Gallo, Paolo

“…Microglia (MG) is suggested to play an immunopathological role of in Multiple Sclerosis (MS). Since hyper-reflective foci (HRF) might mark MG activation,…”
Get full text

Cortical diffusion-tensor imaging abnormalities in multiple sclerosis: a 3-year longitudinal study by Calabrese, Massimiliano, Rinaldi, Francesca, Seppi, Dario, Favaretto, Alice, Squarcina, Letizia, Mattisi, Irene, Perini, Paola, Bertoldo, Alessandra, Gallo, Paolo

“…To evaluate whether diffusion-tensor imaging can be combined with double inversion recovery to improve the detection of structural changes occurring in the…”
Get full text

A comparison of natalizumab’s effects on SDMT between pediatric-onset and adult-onset multiple sclerosis patients by Puthenparampil, Marco, Scialpi, Graziana, Gaggiola, Marta, Zanotelli, Giovanni, Miscioscia, Alessandro, Berardi, Angela, Riccardi, Alice, Nosadini, Margherita, Sartori, Stefano, Perini, Paola, Rinaldi, Francesca, Gallo, Paolo

“…Pediatric-onset multiple sclerosis (POMS) patients often exhibit a wide range of cognitive deficits. Therefore, therapeutic approaches should aim not only to…”
Get full text

D-KEFS ST Failure Identifies Multiple Sclerosis Patients With Worse Objective and Self-Perceived Physical and Cognitive Disability by Riccardi, Alice, Puthenparampil, Marco, Rinaldi, Francesca, Ermani, Mario, Perini, Paola, Gallo, Paolo

“…The Brief Repeatable Battery of Neuropsychological Test (BRB-NT) does not explore the executive functions. We combined BRB-NT and Delis-Kaplan Executive…”
Get full text

Slowly Progressive Optic Perineuritis as the First Clinical Manifestation of Sarcoidosis by Garrì, Federica, Rinaldi, Francesca, Perini, Paola, Miscioscia, Alessandro, Simonato, Davide, Pizzi, Marco, Margoni, Monica, Gallo, Paolo

Get full text

Cortical atrophy is relevant in multiple sclerosis at clinical onset by CALABRESE, Massimiliano, ATZORI, Matteo, BATTISTIN, Leontino, GALLO, Paolo, BERNARDI, Valentina, MORRA, Aldo, ROMUALDI, Chiara, RINALDI, Luciano, MCAULIFFE, Matthew J. M, BARACHINO, Luigi, PERINI, Paola, FISCHL, Bruce

“…Increasing evidence suggests relevant cortical gray matter pathology in patients with Multiple Sclerosis (MS), but how early this pathology begins; its impact…”
Get full text

Wide Cytokine Analysis in Cerebrospinal Fluid at Diagnosis Identified CCL-3 as a Possible Prognostic Factor for Multiple Sclerosis by Puthenparampil, Marco, Stropparo, Erica, Zywicki, Sofia, Bovis, Francesca, Cazzola, Chiara, Federle, Lisa, Grassivaro, Francesca, Rinaldi, Francesca, Perini, Paola, Sormani, Maria Pia, Gallo, Paolo

“…Apart from IgG oligoclonal bands, no other biomarker has, to date, been validated for diagnostic and/or prognostic purposes in multiple sclerosis (MS). To…”
Get full text

Clinical Profiles in Multiple Sclerosis: Cognitive Reserve and Motor Impairment along Disease Duration by Maffezzini, Sabrina, Pucci, Veronica, Riccardi, Alice, Montemurro, Sonia, Puthenparampil, Marco, Perini, Paola, Rinaldi, Francesca, Gallo, Paolo, Arcara, Giorgio, Mondini, Sara

“…(i) Background: Cognitive impairment in people with multiple sclerosis (MS) has been studied in relation to certain clinical variables (e.g., motor disability…”
Get full text

Alemtuzumab following natalizumab is more effective in adult-onset than paediatric-onset multiple sclerosis by Puthenparampil, Marco, Gaggiola, Marta, Miscioscia, Alessandro, Mauceri, Valentina Annamaria, De Napoli, Federica, Zanotelli, Giovanni, Anglani, Mariagiulia, Nosadini, Margherita, Sartori, Stefano, Perini, Paola, Rinaldi, Francesca, Gallo, Paolo

“…Background: Paediatric-onset multiple sclerosis (POMS) therapeutic approach derives from of adult-onset multiple sclerosis (AOMS) tailored algorithms…”
Get full text

Designing a Self-Perception Cognitive Questionnaire for Italian Multiple Sclerosis Patients (Sclerosi Multipla Autovalutazione Cognitiva, SMAC). A Preliminary Exploratory Pilot Study by Riccardi, Alice, Ognibene, Francesca, Mondini, Sara, Nucci, Massimo, Margoni, Monica, Meglioranzi, Ilaria, Carta, Elisa, Zywicki, Sofia, Miante, Silvia, Perini, Paola, Rinaldi, Francesca, Puthenparampil, Marco, Gallo, Paolo

“…Background: Although cognition in multiple sclerosis (MS) is assessed by means of several neuropsychological tests, only a few tools exist to investigate…”
Get full text

Predicted Expenditure for Prescription Drugs for Multiple Sclerosis in the Italian Market Between 2023 and 2028: Results of the Oracle Project by Paolicelli, Damiano, Borriello, Giovanna, Clerici, Raffaella, Colombo, Elena, Croce, Davide, D’Amico, Emanuele, De Rossi, Nicola, Di Sapio, Alessia, Fenu, Giuseppe, Maimone, Davide, Marfia, Girolama A., Moccia, Marcello, Perini, Paola, Piscaglia, Maria G., Razzolini, Lorenzo, Riccaboni, Massimo, Signoriello, Elisabetta, Agostoni, Gianluca, Farina, Alberto, Mondino, Margaret, Berruto, Francesco, Tettamanti, Alessia, Donnaloja, Francesca, Tortorella, Carla

“…Introduction Multiple sclerosis (MS) is a chronic neurodegenerative disease that leads to impaired cognitive function and accumulation of disability, with…”
Get full text

Decreased platelet number in multiple sclerosis during alemtuzumab infusion: a common, transient and clinically silent phenomenon by Puthenparampil, Marco, Rinaldi, Francesca, Federle, Lisa, Cazzola, Chiara, Perini, Paola, Gallo, Paolo

“…Background The cause and clinical significance of the transient decrease in platelet (PLT) count observed in relapsing remitting multiple sclerosis (RRMS)…”
Get full text

Sexual Dysfunction in Multiple Sclerosis: The Role of Executive Function by Marinetto, Silvia, Riccardi, Alice, Barbadoro, Filippo, Pucci, Veronica, Selini, Enrico, Pavan, Aghite, Rinaldi, Francesca, Perini, Paola, Puthenparampil, Marco, Gallo, Paolo, Mondini, Sara

“…Cognitive impairment and sexual dysfunction are common symptoms in persons with Multiple Sclerosis (MS). The present study focuses on the relationship between…”
Get full text

Characterization of SURF-1 Expression and Surf-1p Function in Normal and Disease Conditions by Tiranti, Valeria, Galimberti, Claudia, Nijtmans, Leo, Bovolenta, Silvia, Paola Perini, Maria, Zeviani, Massimo

“…Loss-of-function mutations of the SURF-1 gene have been associated with Leigh syndrome with cytochrome c oxidase (COX) deficiency. Mature Surf-1 protein…”
Get full text

Cyclophosphamide-based combination therapies for autoimmunity by Perini, Paola, Calabrese, Massimiliano, Rinaldi, Luciano, Gallo, Paolo

“…Immunomodulatory agent (IMA)-unresponsive multiple sclerosis (MS) can quickly evolve to a dramatic and irreversible disability. Treating these patients with…”
Get full text

Disease-Modifying Drugs Reduce Cortical Lesion Accumulation and Atrophy Progression in Relapsing-Remitting Multiple Sclerosis: Results from a 48-Month Extension Study by Seppi, Dario, Favaretto, Alice, Atzori, Matteo, Perini, Paola, Rinaldi, Francesca, Gallo, Paolo

“…Cortical lesions (CLs) and atrophy are pivotal in multiple sclerosis (MS) pathology. This study determined the effect of disease modifying drugs (DMDs) on CL…”
Get full text