Search Results - "Panzner, Matthew J"

A binuclear Zn(II)-Zn(II) complex from a 2-hydroxybenzohydrazide-derived Schiff base for selective detection of pyrophosphate by Wang, Junfeng, Liu, Bin, Liu, Xiumin, Panzner, Matthew J, Wesdemiotis, Chrys, Pang, Yi

“…A hydroxybenzohydrazide-based Schiff base ligand was conveniently synthesized. Upon addition of Zn(2+) cations, the ligand exhibited a high tendency to form a…”
Get more information

Host-guest assembly of squaraine dye in cucurbit[8]uril: its implication in fluorescent probe for mercury ions by Xu, Yongqian, Panzner, Matthew J, Li, Xiaopeng, Youngs, Wiley J, Pang, Yi

“…The binding interactions between SQ2 squaraine dye and cucurbit[8]uril (CB8) effectively removes the aggregation of SQ2 in aqueous solution by forming a 1 : 1…”
Get more information

Synthesis from Caffeine of a Mixed N-Heterocyclic Carbene−Silver Acetate Complex Active against Resistant Respiratory Pathogens by Kascatan-Nebioglu, Aysegul, Melaiye, Abdulkareem, Hindi, Khadijah, Durmus, Semih, Panzner, Matthew J, Hogue, Lisa A, Mallett, Rebekah J, Hovis, Christine E, Coughenour, Marvin, Crosby, Seth D, Milsted, Amy, Ely, Daniel L, Tessier, Claire A, Cannon, Carolyn L, Youngs, Wiley J

“…The bis(N-heterocyclic carbene) (NHC) silver complex, 3, with a methyl carbonate anion was formed from the reaction of the iodide salt of methylated caffeine,…”
Get full text

Silver Binding to Bacterial Glutaredoxins Observed by NMR by Bilinovich, Stephanie M., Morris, Daniel L., Prokop, Jeremy W., Caporoso, Joel A., Taraboletti, Alexandra, Duangjumpa, Nilubol, Panzner, Matthew J., Shriver, Leah P., Leeper, Thomas C.

“…Glutaredoxins (GRXs) are a class of enzymes used in the reduction of protein thiols and the removal of reactive oxygen species. The CPYC active site of GRX is…”
Get full text

An NMR-Guided Screening Method for Selective Fragment Docking and Synthesis of a Warhead Inhibitor by Khattri, Ram B, Morris, Daniel L, Davis, Caroline M, Bilinovich, Stephanie M, Caras, Andrew J, Panzner, Matthew J, Debord, Michael A, Leeper, Thomas C

“…Selective hits for the glutaredoxin ortholog of Brucella melitensis are determined using STD NMR and verified by trNOE and (15)N-HSQC titration. The most…”
Get full text

Synthesis and Structural Characterization of N-Heterocyclic Carbene Complexes of Silver(I) and Rhodium(I) from Caffeine by Kascatan-Nebioglu, Aysegul, Panzner, Matthew J, Garrison, Jered C, Tessier, Claire A, Youngs, Wiley J

“…The imidazolium cation 1,3,7,9-tetramethylxanthinium methyl sulfate (1a) is obtained by the reaction of caffeine with dimethyl sulfate. The anion exchange of…”
Get full text

The Medicinal Applications of Imidazolium Carbene−Metal Complexes by Hindi, Khadijah M, Panzner, Matthew J, Tessier, Claire A, Cannon, Carolyn L, Youngs, Wiley J

“…The application of imidazolium carbene-metal complexes as chemotherapeutic agents is discussed. Such metal-based pharmaceuticals inhibit tumor cell growth…”
Get full text

Investigation of Phosphazene Superbase Interactions with [PCl2N]3 by Johnson, Nicholas A., Xue, Yuan, Panzner, Matthew J., Youngs, Wiley J., Tessier, Claire A.

“…In this study, the reaction between phosphazene superbases and a chlorophosphazene trimer ([PCl2N]3) has been investigated. In this room temperature reaction,…”
Get full text

Synthesis and Characterization of Cobalt(II) N,N′‑Diphenylazodioxide Complexes by Emhoff, Kylin A, Balaraman, Lakshmi, Simpson, Sydney R, Stromyer, Michael L, Kalil, Haitham F, Beemiller, James R, Sikatzki, Philipp, Eshelman, Teya S, Salem, Ahmed M. H, DeBord, Michael A, Panzner, Matthew J, Youngs, Wiley J, Boyd, W. Christopher

“…Removal of chloride from CoCl2 with TlPF6 in acetonitrile, followed by addition of excess nitrosobenzene, yielded the eight-coordinate cobalt­(II) complex salt…”
Get full text

Anticancer Activity of Ag(I) N-Heterocyclic Carbene Complexes Derived from 4,5-Dichloro-1H-Imidazole by Medvetz, Doug A., Hindi, Khadijah M., Panzner, Matthew J., Ditto, Andrew J., Yun, Yang H., Youngs, Wiley J.

“…A class of Ag(I) N-heterocyclic carbene silver complexes, 1–3, derived from 4,5-dichloro-1H-imidazole has been evaluated for their anticancer activity against…”
Get full text

N-Heterocyclic carbene–silver complexes: A new class of antibiotics by Kascatan-Nebioglu, Aysegul, Panzner, Matthew J., Tessier, Claire A., Cannon, Carolyn L., Youngs, Wiley J.

“…N-Heterocyclic carbene (NHC)–silver complexes were synthesized from pyridine linked pincer ligands and methylated caffeine. Pincer NHC–silver complexes were…”
Get full text

Ovarian Cancer Activity of Cyclic Amine and Thiaether Metal Complexes by Medvetz, Doug A, Stakleff, Kimberly D, Schreiber, Tara, Custer, Paul D, Hindi, Khadijah, Panzner, Matthew J, Blanco, Denise D, Taschner, Michael J, Tessier, Claire A, Youngs, Wiley J

“…A thiaether metal complex 1-aza-4,7-dithiacyclononane-RhCl3, 2, and cyclic amine metal complexes tacn−CuBr2, 3, and Me3tacn−RuCl3, 4, have been evaluated for…”
Get full text

Arylethynyl Substituted 9,10-Anthraquinones:  Tunable Stokes Shifts by Substitution and Solvent Polarity by Yang, Jinhua, Dass, Amala, Rawashdeh, Abdel-Monem M, Sotiriou-Leventis, Chariklia, Panzner, Matthew J, Tyson, Daniel S, Kinder, James D, Leventis, Nicholas

“…2-Arylethynyl- and 2,6- and 2,7-diarylethynyl-substituted 9,10-anthraquinones were synthesized via Sonogashira coupling reactions of 2-bromo-, 2,6-dibromo-,…”
Get full text

In vitro antimicrobial studies of silver carbene complexes: activity of free and nanoparticle carbene formulations against clinical isolates of pathogenic bacteria by Leid, Jeff G., Ditto, Andrew J., Knapp, Amanda, Shah, Parth N., Wright, Brian D., Blust, Robyn, Christensen, Lanette, Clemons, C. B., Wilber, J. P., Young, Gerald W., Kang, Ae Gyeong, Panzner, Matthew J., Cannon, Carolyn L., Yun, Yang H., Youngs, Wiley J., Seckinger, Nicole M., Cope, Emily K.

“…Objectives Silver carbenes may represent novel, broad-spectrum antimicrobial agents that have low toxicity while providing varying chemistry for targeted…”
Get full text

Synthesis, Stability, and Antimicrobial Studies of Electronically Tuned Silver Acetate N-Heterocyclic Carbenes by Hindi, Khadijah M, Siciliano, Tammy J, Durmus, Semih, Panzner, Matthew J, Medvetz, Doug A, Reddy, D. Venkat, Hogue, Lisa A, Hovis, Christine E, Hilliard, Julia K, Mallet, Rebekah J, Tessier, Claire A, Cannon, Carolyn L, Youngs, Wiley J

“…A series of methylated imidazolium salts with varying substituents on the 4 and 5 positions of the imidazole ring were synthesized. These salts were reacted…”
Get full text

Synthesis, characterization, in vitro SAR study, and preliminary in vivo toxicity evaluation of naphthylmethyl substituted bis-imidazolium salts by Southerland, Marie R., DeBord, Michael A., Johnson, Nicholas A., Crabtree, Steven R., Alexander, Nicolas E., Stromyer, Michael L., Wagers, Patrick O., Panzner, Matthew J., Wesdemiotis, Chrys, Shriver, Leah P., Tessier, Claire A., Youngs, Wiley J.

“…[Display omitted] A series of novel bis-imidazolium salts was synthesized, characterized, and evaluated in vitro against a panel of non-small cell lung cancer…”
Get full text

The antimicrobial efficacy of sustained release silver–carbene complex-loaded l -tyrosine polyphosphate nanoparticles: Characterization, in vitro and in vivo studies by Hindi, Khadijah M, Ditto, Andrew J, Panzner, Matthew J, Medvetz, Douglas A, Han, Daniel S, Hovis, Christine E, Hilliard, Julia K, Taylor, Jane B, Yun, Yang H, Cannon, Carolyn L, Youngs, Wiley J

“…Abstract The pressing need to treat multi-drug resistant bacteria in the chronically infected lungs of cystic fibrosis (CF) patients has given rise to novel…”
Get full text

Synthesis, anti-proliferative activity, SAR study, and preliminary in vivo toxicity study of substituted N,N′-bis(arylmethyl)benzimidazolium salts against a panel of non-small cell lung cancer cell lines by Shelton, Kerri L., DeBord, Michael A., Wagers, Patrick O., Southerland, Marie R., Williams, Travis M., Robishaw, Nikki K., Shriver, Leah P., Tessier, Claire A., Panzner, Matthew J., Youngs, Wiley J.

“…[Display omitted] •Hydrophobic and hydrophilic benzimidazolium salts were synthesized/characterized.•Benzimidazolium salts were tested for their anti-cancer…”
Get full text

Silver metallation of hen egg white lysozyme: X-ray crystal structure and NMR studies by Panzner, Matthew J, Bilinovich, Stephanie M, Youngs, Wiley J, Leeper, Thomas C

“…The X-ray crystal structure, NMR binding studies, and enzyme activity of silver(I) metallated hen egg white lysozyme are presented. Primary bonding of silver…”
Get more information

Synthesis, Characterization, and In Vivo Efficacy of Shell Cross-Linked Nanoparticle Formulations Carrying Silver Antimicrobials as Aerosolized Therapeutics by Shah, Parth N, Lin, Lily Yun, Smolen, Justin A, Tagaev, Jasur A, Gunsten, Sean P, Han, Daniel S, Heo, Gyu Seong, Li, Yali, Zhang, Fuwu, Zhang, Shiyi, Wright, Brian D, Panzner, Matthew J, Youngs, Wiley J, Brody, Steven L, Wooley, Karen L, Cannon, Carolyn L

“…The use of nebulizable, nanoparticle-based antimicrobial delivery systems can improve efficacy and reduce toxicity for treatment of multi-drug-resistant…”
Get full text