Search Results - "Panus, P C"

Regulation of xanthine dehydrogenase and xanthine oxidase activity by hypoxia by Poss, W B, Huecksteadt, T P, Panus, P C, Freeman, B A, Hoidal, J R

“…The present study determined the effect of hypoxia on xanthine dehydrogenase (XDH) and xanthine oxidase (XO) activity and gene and protein expression in…”
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Formulation and in vitro evaluation of niacin-loaded nanoparticles to reduce prostaglandin mediated vasodilatory flushing by Cooper, D L, Carmical, J A, Panus, P C, Harirforoosh, S

“…Niacin, activating G-protein coupled receptor (GPR) 109A, stimulates release of vasodilatory prostaglandins (PGs) such as PGE2 which can elicit…”
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Assessment of celecoxib poly(lactic-co-glycolic) acid nanoformulation on drug pharmacodynamics and pharmacokinetics in rats by Harirforoosh, S, West, K O, Murrell, D E, Denham, J W, Panus, P C, Hanley, G A

“…Celecoxib (CEL) is a nonsteroidal anti-inflammatory drug (NSAID) showing selective cycloxygenase-2 inhibition. While effective as a pain reducer, CEL exerts…”
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Celecoxib or diclofenac hepatic status in the presence or absence of rebamipide by Murrell, D E, Rahmasari, Y, Denham, J W, Panus, P C, Harirforoosh, S

“…Utilization of nonsteroidal anti-inflammatory drugs (NSAIDs), such as diclofenac, can produce gastrointestinal ulceration. Thus, cyclooxygenase-2-selective…”
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Detection of H2O2 release from vascular endothelial cells by Panus, P C, Radi, R, Chumley, P H, Lillard, R H, Freeman, B A

“…Endothelial cells are both significant sources and targets of reactive oxygen species, including O2.-, H2O2, .OH, .NO, and ONOO-, which play important roles in…”
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Cathodic iontophoresis of ketoprofen over the equine middle carpal joint by EASTMAN, T., PANUS, P. C., HONNAS, C. M., FERSLEW, K. E., BLACKFORD, J., DOHERTY, T. J.

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Development of O2 tolerance in rabbits with no increase in antioxidant enzymes by Baker, R R, Holm, B A, Panus, P C, Matalon, S

“…Instillation of exogenous surfactant into rabbits exposed to 100% O2 increases survival time and decreases alveolar epithelial injury. In this study we…”
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Effects of Iontophoresis Current Magnitude and Duration on Dexamethasone Deposition and Localized Drug Retention by Anderson, Carter R, Morris, Russell L, Boeh, Stephen D, Panus, Peter C, Sembrowich, Walter L

“…Iontophoresis is a process that uses bipolar electric fields to propel molecules across intact skin and into underlying tissue. The purpose of this study was…”
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The contribution of vascular endothelial xanthine dehydrogenase/oxidase to oxygen-mediated cell injury by Panus, P C, Wright, S A, Chumley, P H, Radi, R, Freeman, B A

“…The conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) and the reaction of XO-derived partially reduced oxygen species (PROS) have been…”
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Endogenous xanthine oxidase-derived O2 metabolites inhibit surfactant metabolism by Baker, R R, Panus, P C, Holm, B A, Engstrom, P C, Freeman, B A, Matalon, S

“…The ability of xanthine oxidase (XO)-derived, partially reduced O2 species (PROS) to inhibit surfactant production was examined in freshly isolated alveolar…”
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The periodicity of vascular access thrombosis by Diskin, C J, Stokes, T J, Panus, L W, Panus, P C

“…A periodicity has been observed in thrombotic events that occur in a variety of vascular beds. There also has been a recent suggestion that there is an…”
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Characterization of cultured alveolar epithelial cell xanthine dehydrogenase/oxidase by Panus, P C, Burgess, B, Freeman, B A

“…Conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) and the toxic reactions of subsequent XO-derived superoxide, hydrogen peroxide and hydroxyl…”
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Iontophoresis of dexamethosone-phosphate into the equine tibiotarsal joint by Blackford, J, Doherty, T J, Ferslew, K E, Panus, P C

“…In human rehabilitation medicine, dexamethasone-phosphate is theoretically iontophoresed to localized subcutaneous tissue where conversion to dexamethasone…”
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Responses of Type II Pneumocyte Antioxidant Enzymes to Normoxic and Hyperoxic Culture by Panus, Peter C., Matalon, Sadis, Freeman, Bruce A.

“…Cultured type II pneumocyte responses to in vitro normoxia (95% air:5% CO₂) or hyperoxia (95% O₂:5% CO₂) were quantified. Normoxic culture (0 to 96 h) of…”
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Correction for Ties by Panus, Peter C, Chan, Yvonne

“…To the Editor: In reading the article "Learning and Understanding the Kruskal-Wallis One-Way Analysis-of-Variance-by-Ranks Test for Differences Among Three or…”
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Inhibition of neutrophil response by mepacrine by Panus, P C, Jones, H P

“…Clinical and experimental evidence supports neutrophil involvement in the pulmonary complications of adult respiratory distress syndrome. Preliminary evidence…”
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Failure to Detect Dexamethasone Phosphate in the Local Venous Blood Postcathodic Iontophoresis in Humans by Smutok, Michael A., Mayo, Michele F., Gabaree, Catherine L ., Ferslew, Kenneth E., Panus, Peter C.

“…Study Design: A single-blind, 2-factor (4 treatments by 8 time points) repeated-measures study design. Objective: To analytically determine dexamethasone and…”
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Transdermal iontophoretic delivery of ketoprofen through human cadaver skin and in humans by Panus, Peter C, Campbell, Jennifer, Kulkarni, Shirishkumar B, Herrick, Richard T, Ravis, William R, Banga, Ajay K

“…Transdermal iontophoretic delivery of ketoprofen in cadaver skin and healthy volunteers was examined. In vitro anodic and cathodic iontophoresis (0.5 mA/cm 2,…”
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Ketoprofen Tissue Permeation in Swine Following Cathodic Iontophoresis by Panus, P C, Ferslew, K E, Tober-Meyer, B, Kao, R L

“…Pharmacokinetic assessment of drug tissue permeation following iontophoresis is limited. The depth of ketoprofen tissue permeation following cathodic…”
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Normalized forces and active range of motion in unilateral radial epicondylalgia (tennis elbow) by Benjamin, S J, Williams, D A, Kalbfleisch, J H, Gorman, P W, Panus, P C

“…Single group pretest-posttest. There is a lack of consensus concerning the preferred assessment and treatment for radial epicondylalgia. Determine whether…”
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