Search Results - "Pantho, Ahmed F."
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Pravastatin Protects Cytotrophoblasts from Hyperglycemia-Induced Preeclampsia Phenotype
Published in Cells (Basel, Switzerland) (13-09-2024)“…There are no effective therapies to prevent preeclampsia (PE). Pravastatin shows promise by attenuating processes associated with PE such as decreased…”
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Mechanism of Marinobufagenin-Induced Hyperpermeability of Human Brain Microvascular Endothelial Cell Monolayer: A Potential Pathogenesis of Seizure in Preeclampsia
Published in Cells (Basel, Switzerland) (30-10-2024)“…Preeclampsia (preE) is a hypertensive disorder in pregnancies. It is the third leading cause of mortality among pregnant women and fetuses worldwide, and there…”
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Cartiotonic steroids affect monolayer permeability in lymphatic endothelial cells
Published in Molecular and cellular biochemistry (01-08-2021)“…Edema is common in preeclampsia (preE), a hypertensive disorder of pregnancy. Cardiotonic steroids (CTSs) such as marinobufagenin (MBG) are involved in the…”
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Reduced urinary angiotensinogen excretion in preeclampsia
Published in Pregnancy hypertension (01-03-2022)“…•Preeclampsia results in reduced urinary angiotensinogen excretion.•Preeclampsia results in reduced plasma levels of angiotensin II.•Preeclampsia results in…”
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Hyperglycemia down-regulates cGMP-dependent protein kinase I expression in first trimester cytotrophoblast cells
Published in Molecular and cellular biochemistry (01-07-2015)“…Diabetes in pregnancy is associated with microvascular complications and a higher incidence of preeclampsia. The regulatory signaling pathways involving nitric…”
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Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells
Published in International journal of environmental research and public health (11-05-2017)“…The cytotrophoblast (CTB) cells of the human placenta have membrane receptors that bind certain cardiotonic steroids (CTS) found in blood plasma. One of these,…”
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Abstract 16: A Novel H2 Relaxin B-Chain-Only Peptide Variant B7-33 Improves The Pathophysiology Of Placental Ischemia In The Reduced Uterine Perfusion Pressure Rat Model Of Preeclampsia
Published in Hypertension (Dallas, Tex. 1979) (01-09-2024)“…Abstract only Background: Preeclampsia (PE) is a hypertensive pregnancy disorder, which occurs in approximately 10% of all gestations. The literature suggests…”
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RELAXIN LIKE PEPTIDE B7-33 AND IT'S DERIVATIVES DEMONSTRATE EFFICACY IN RODENT MODELS OF PREECLAMPSIA
Published in Journal of hypertension (01-05-2024)“…Objective: Preeclampsia (PreE) is a hypertensive pregnancy disorder, which occurs in approximately 10% of all gestations. The literature suggests potential…”
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Abstract P426: Novel Peptide B7-33 Demonstrates Efficacy In Rat Models Of Preeclampsia
Published in Hypertension (Dallas, Tex. 1979) (01-09-2023)“…Abstract only Background: Preeclampsia (PreE) is a hypertensive pregnancy disorder, which occurs in approximately 10% of all gestations. The literature…”
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Abstract P104: Neutralization Of Marinobufagenin Demonstrates Efficacy In Vitro And In Vivo In Models Of Preeclampsia
Published in Hypertension (Dallas, Tex. 1979) (01-09-2022)“…Abstract only Objective: Marinobufagenin (MBG), a cardiotonic steroid, is distinctly elevated in preeclampsia (preE) and may directly contribute to…”
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Abstract P3042: Novel Peptide B7-33 and It's Lipidated Derivative Protect Cytotrophoblasts From Preeclampsia Phenotype in a Cellular Model of the Syndrome
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only Background: Preeclampsia (PreE) is a pregnancy disorder characterized by new onset of hypertension and reduced fetal weight. We have previously…”
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Abstract P154: Plasma and Placental (Pro)Renin and Soluble (Pro)Renin Receptor are Upregulated in Preeclamptic Pregnancy
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only Objective: Preeclampsia (preE), a syndrome of hypertension, and end organ damage, is a leading cause of maternal and fetal morbidity and…”
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316: Novel anti-MBG antibodies protect cytotrophoblast cells from a marinobufagenin-induced preeclampsia phenotype
Published in American journal of obstetrics and gynecology (01-01-2018)Get full text
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Abstract P640: A Single-Chain Derivative of the Realaxin Hormone (B7-33) Protects Cytotrophoblasts from Hyperglycemia-Induced Preeclampsia Phenotype and Induces the Survival Pathway
Published in Hypertension (Dallas, Tex. 1979) (01-09-2016)“…Abstract only Background: Relaxin is a peptide hormone that allows vasodilation and plays an important role in the process of parturition. The literature…”
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