Search Results - "Panoutsopoulou, Konstantina"
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Epigenetic regulation of MIR145 core promoter controls miR-143/145 cluster in bladder cancer progression and treatment outcome
Published in Molecular therapy. Nucleic acids (13-12-2022)“…Owing to its highly heterogeneous molecular landscape, bladder cancer (BlCa) is still characterized by non-personalized treatment and lifelong surveillance…”
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2
Cancer quiescence: non-coding RNAs in the spotlight
Published in Trends in molecular medicine (01-10-2023)“…Cancer quiescence is defined as a dynamic and reversible slow-cycling or mitotically arrested cell state, serving as the hallmark of cancer dormancy.Cancer…”
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3
Repression of miR-146a in predicting poor treatment outcome in triple-negative breast cancer
Published in Clinical biochemistry (01-04-2023)“…•miR-146a repression is associated with poor survival in triple-negative breast cancer.•Loss of miR-146a increases the risk for post-treatment early-recurrence…”
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4
tRNA-derived small RNA 3'U-tRFValCAC promotes tumour migration and early progression in ovarian cancer
Published in European journal of cancer (1990) (01-02-2023)“…INTRODUCTIONDespite recent advances in epithelial ovarian cancer (EOC) management, the highly heterogenous histological/molecular tumour background and…”
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5
tRNA-derived small RNA 3′U-tRFValCAC promotes tumour migration and early progression in ovarian cancer
Published in European journal of cancer (1990) (01-02-2023)“…Despite recent advances in epithelial ovarian cancer (EOC) management, the highly heterogenous histological/molecular tumour background and patients' treatment…”
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6
Unraveling UCA1 lncRNA prognostic utility in urothelial bladder cancer
Published in Carcinogenesis (New York) (22-08-2019)“…Abstract In the era of precision oncology, bladder cancer (BlCa) is characterized by generic patient management and lack of personalized prognosis and…”
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7
The interplay between miR-1245a and BRCA2 in colorectal cancer
Published in Annals of translational medicine (01-09-2020)Get full text
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8
miR‐181a overexpression predicts the poor treatment response and early‐progression of serous ovarian cancer patients
Published in International journal of cancer (15-12-2020)“…Ovarian cancer (OC) remains a leading cause of gynecological cancer‐related death worldwide, characterized by poor 5‐year survival. Molecular markers could…”
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9
miR-203 is an independent molecular predictor of prognosis and treatment outcome in ovarian cancer: a multi-institutional study
Published in Carcinogenesis (New York) (17-06-2020)“…miR-203 overexpression in ovarian tumors is associated with disease progression and worse patient’s survival, independently of FIGO stage, grade, residual…”
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10
tRNAGlyGCC-Derived Internal Fragment (i-tRF-GlyGCC) in Ovarian Cancer Treatment Outcome and Progression
Published in Cancers (22-12-2021)“…Epithelial ovarian cancer (EOC) remains a highly-lethal gynecological malignancy, characterized by frequent recurrence, chemotherapy resistance and poor 5-year…”
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11
Epi‐miRNAs: Modern mediators of methylation status in human cancers
Published in Wiley interdisciplinary reviews. RNA (01-03-2023)“…Methylation of the fundamental macromolecules, DNA/RNA, and proteins, is remarkably abundant, evolutionarily conserved, and functionally significant in…”
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12
Combined Treatment With Exenatide and Cyclosporine A or Parstatin 1-26 Results in Enhanced Reduction of Infarct Size in a Rabbit Model
Published in Journal of cardiovascular pharmacology (01-07-2017)“…Exenatide and cyclosporine A have been shown to moderately protect against myocardial reperfusion injury leading to reduction of infarct size in patients. Our…”
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13
Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming
Published in Journal of translational medicine (03-03-2023)“…Chemotherapy (CT) is central to the treatment of triple negative breast cancer (TNBC), but drug toxicity and resistance place strong restrictions on treatment…”
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14
tRNA GlyGCC -Derived Internal Fragment (i-tRF-GlyGCC) in Ovarian Cancer Treatment Outcome and Progression
Published in Cancers (22-12-2021)“…Epithelial ovarian cancer (EOC) remains a highly-lethal gynecological malignancy, characterized by frequent recurrence, chemotherapy resistance and poor 5-year…”
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15
Association of high miR-27a, miR-206, and miR-214 expression with poor patient prognosis and increased chemoresistance in triple-negative breast cancer
Published in American journal of cancer research (01-01-2023)“…Triple-negative breast cancer (TNBC) represents the most aggressive breast cancer subtype, associated with early metastasis and recurrence as well as poor…”
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16
TCRs genetically linked to CD28 and CD3ε do not mispair with endogenous TCR chains and mediate enhanced T cell persistence and anti-melanoma activity
Published in The Journal of immunology (1950) (15-11-2014)“…Adoptive transfer of T cells that are gene engineered to express a defined TCR represents a feasible and promising therapy for patients with tumors. However,…”
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17
CDKN2A copy number alteration in bladder cancer: Integrative analysis in patient-derived xenografts and cancer patients
Published in Molecular Therapy: Oncology (20-06-2024)“…Bladder cancer (BlCa) is an extensively heterogeneous disease that leads to great variability in tumor evolution scenarios and lifelong patient surveillance,…”
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18
tRNA-derived small RNA 3'U-tRF ValCAC promotes tumour migration and early progression in ovarian cancer
Published in European journal of cancer (1990) (01-02-2023)“…Despite recent advances in epithelial ovarian cancer (EOC) management, the highly heterogenous histological/molecular tumour background and patients' treatment…”
Get full text
Journal Article -
19
The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells
Published in Oncotarget (30-04-2014)“…In early stages of metastasis malignant cells must acquire phenotypic changes to enhance their migratory behavior and their ability to breach the matrix…”
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