Search Results - "Pannequin, Julie"

FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell by Relier, Sébastien, Ripoll, Julie, Guillorit, Hélène, Amalric, Amandine, Achour, Cyrinne, Boissière, Florence, Vialaret, Jérôme, Attina, Aurore, Debart, Françoise, Choquet, Armelle, Macari, Françoise, Marchand, Virginie, Motorin, Yuri, Samalin, Emmanuelle, Vasseur, Jean-Jacques, Pannequin, Julie, Aguilo, Francesca, Lopez-Crapez, Evelyne, Hirtz, Christophe, Rivals, Eric, Bastide, Amandine, David, Alexandre

“…Cancer stem cells (CSCs) are a small but critical cell population for cancer biology since they display inherent resistance to standard therapies and give rise…”
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A stem cell population at the anorectal junction maintains homeostasis and participates in tissue regeneration by Mitoyan, Louciné, Chevrier, Véronique, Hernandez-Vargas, Hector, Ollivier, Alexane, Homayed, Zeinab, Pannequin, Julie, Poizat, Flora, De Biasi-Cador, Cécile, Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Guasch, Géraldine

“…At numerous locations of the body, transition zones are localized at the crossroad between two types of epithelium and are frequently associated with neoplasia…”
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Sox9 Regulates Cell Proliferation and Is Required for Paneth Cell Differentiation in the Intestinal Epithelium by Bastide, Pauline, Darido, Charbel, Pannequin, Julie, Kist, Ralf, Robine, Sylvie, Marty-Double, Christiane, Bibeau, Frédéric, Scherer, Gerd, Joubert, Dominique, Hollande, Frédéric, Blache, Philippe, Jay, Philippe

“…The HMG-box transcription factor Sox9 is expressed in the intestinal epithelium, specifically, in stem/ progenitor cells and in Paneth cells. Sox9 expression…”
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CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma by Giraud, Julie, Seeneevassen, Lornella, Rousseau, Benoit, Bouriez, Damien, Sifré, Elodie, Giese, Alban, Nguyen, Tra Ly, Tiffon, Camille, Lippi, Yannick, Azzi-Martin, Lamia, Pannequin, Julie, Ménard, Armelle, Bessède, Emilie, Staedel, Cathy, Mégraud, Francis, Belleannée, Geneviève, Lehours, Philippe, Gronnier, Caroline, Dubus, Pierre, Varon, Christine

“…Background Cancer stem cells (CSCs) are at the origin of tumour initiation and progression in gastric adenocarcinoma (GC). However, markers of…”
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Regulation of Src tumor activity by its N-terminal intrinsically disordered region by Aponte, Emilie, Lafitte, Marie, Sirvent, Audrey, Simon, Valérie, Barbery, Maud, Fourgous, Elise, Boublik, Yvan, Maffei, Mariano, Armand, Florence, Hamelin, Romain, Pannequin, Julie, Fort, Philippe, Pons, Miquel, Roche, Serge

“…The membrane-anchored Src tyrosine kinase is involved in numerous pathways and its deregulation is involved in human cancer. Our knowledge on Src regulation…”
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Inhibition of DDR1‐BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer by Jeitany, Maya, Leroy, Cédric, Tosti, Priscillia, Lafitte, Marie, Le Guet, Jordy, Simon, Valérie, Bonenfant, Debora, Robert, Bruno, Grillet, Fanny, Mollevi, Caroline, El Messaoudi, Safia, Otandault, Amaëlle, Canterel‐Thouennon, Lucile, Busson, Muriel, Thierry, Alain R, Martineau, Pierre, Pannequin, Julie, Roche, Serge, Sirvent, Audrey

“…The clinical management of metastatic colorectal cancer (mCRC) faces major challenges. Here, we show that nilotinib, a clinically approved drug for chronic…”
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Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme by Jacquemin, Guillaume, Wurmser, Annabelle, Huyghe, Mathilde, Sun, Wenjie, Homayed, Zeinab, Merle, Candice, Perkins, Meghan, Qasrawi, Fairouz, Richon, Sophie, Dingli, Florent, Arras, Guillaume, Loew, Damarys, Vignjevic, Danijela, Pannequin, Julie, Fre, Silvia

“…Tumours are complex ecosystems composed of different types of cells that communicate and influence each other. While the critical role of stromal cells in…”
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Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells by Paquet-Fifield, Sophie, Koh, Shir Lin, Cheng, Lesley, Beyit, Laura M, Shembrey, Carolyn, Mølck, Christina, Behrenbruch, Corina, Papin, Marina, Gironella, Meritxell, Guelfi, Sophie, Nasr, Ramona, Grillet, Fanny, Prudhomme, Michel, Bourgaux, Jean-Francois, Castells, Antoni, Pascussi, Jean-Marc, Heriot, Alexander G, Puisieux, Alain, Davis, Melissa J, Pannequin, Julie, Hill, Andrew F, Sloan, Erica K, Hollande, Frédéric

“…Posttreatment recurrence of colorectal cancer, the third most lethal cancer worldwide, is often driven by a subpopulation of cancer stem cells (CSC). The tight…”
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Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance by Therizols, Gabriel, Bash-Imam, Zeina, Panthu, Baptiste, Machon, Christelle, Vincent, Anne, Ripoll, Julie, Nait-Slimane, Sophie, Chalabi-Dchar, Mounira, Gaucherot, Angéline, Garcia, Maxime, Laforêts, Florian, Marcel, Virginie, Boubaker-Vitre, Jihane, Monet, Marie-Ambre, Bouclier, Céline, Vanbelle, Christophe, Souahlia, Guillaume, Berthel, Elise, Albaret, Marie Alexandra, Mertani, Hichem C., Prudhomme, Michel, Bertrand, Martin, David, Alexandre, Saurin, Jean-Christophe, Bouvet, Philippe, Rivals, Eric, Ohlmann, Théophile, Guitton, Jérôme, Dalla Venezia, Nicole, Pannequin, Julie, Catez, Frédéric, Diaz, Jean-Jacques

“…Mechanisms of drug-tolerance remain poorly understood and have been linked to genomic but also to non-genomic processes. 5-fluorouracil (5-FU), the most widely…”
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Correction to: Regulation of Src tumor activity by its N-terminal intrinsically disordered region by Aponte, Emilie, Lafitte, Marie, Sirvent, Audrey, Simon, Valérie, Barbery, Maud, Fourgous, Elise, Boublik, Yvan, Maffei, Mariano, Armand, Florence, Hamelin, Romain, Pannequin, Julie, Fort, Philippe, Pons, Miquel, Roche, Serge

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Metformin reveals a mitochondrial copper addiction of mesenchymal cancer cells by Müller, Sebastian, Versini, Antoine, Sindikubwabo, Fabien, Belthier, Guillaume, Niyomchon, Supaporn, Pannequin, Julie, Grimaud, Laurence, Cañeque, Tatiana, Rodriguez, Raphaël

“…The clinically approved drug metformin has been shown to selectively kill persister cancer cells through mechanisms that are not fully understood. To provide…”
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Correction: Metformin reveals a mitochondrial copper addiction of mesenchymal cancer cells by Müller, Sebastian, Versini, Antoine, Sindikubwabo, Fabien, Belthier, Guillaume, Niyomchon, Supaporn, Pannequin, Julie, Grimaud, Laurence, Cañeque, Tatiana, Rodriguez, Raphaël

“…[This corrects the article DOI: 10.1371/journal.pone.0206764.]…”
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The p53 isoform Δ133p53β promotes cancer stem cell potential by Arsic, Nikola, Gadea, Gilles, Lagerqvist, E Louise, Busson, Muriel, Cahuzac, Nathalie, Brock, Carsten, Hollande, Frederic, Gire, Veronique, Pannequin, Julie, Roux, Pierre

“…Cancer stem cells (CSC) are responsible for cancer chemoresistance and metastasis formation. Here we report that Δ133p53β, a TP53 splice variant, enhanced…”
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A Label-Free Cell Sorting Approach to Highlight the Impact of Intratumoral Cellular Heterogeneity and Cancer Stem Cells on Response to Therapies by Hervieu, Céline, Verdier, Mireille, Barthout, Elodie, Bégaud, Gaëlle, Christou, Niki, Sage, Magali, Pannequin, Julie, Battu, Serge, Mathonnet, Muriel

“…Cancer stem cells play a crucial role in tumor initiation, metastasis, and resistance to treatment. Cellular heterogeneity and plasticity complicate the…”
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Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling by Bonnans, Caroline, Flacelière, Maud, Grillet, Fanny, Dantec, Christelle, Desvignes, Jean-Pierre, Pannequin, Julie, Severac, Dany, Dubois, Emeric, Bibeau, Frédéric, Escriou, Virginie, Crespy, Philippe, Journot, Laurent, Hollande, Frédéric, Joubert, Dominique

“…β-Arrestins (Arrb) participate in the regulation of multiple signaling pathways, including Wnt/β-catenin, the major actor in human colorectal cancer…”
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Symplekin promotes tumorigenicity by up-regulating claudin-2 expression by Buchert, Michael, Papin, Marina, Bonnans, Caroline, Darido, Charbel, Raye, Warren S, Garambois, Véronique, Pélegrin, André, Bourgaux, Jean-François, Pannequin, Julie, Joubert, Dominique, Hollande, Frédéric

“…Symplekin is a ubiquitously expressed protein involved in cytoplasmic RNA polyadenylation and transcriptional regulation and is localized at tight junctions…”
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Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells by Darido, Charbel, Buchert, Michael, Pannequin, Julie, Bastide, Pauline, Zalzali, Hassan, Mantamadiotis, Theo, Bourgaux, Jean-François, Garambois, Véronique, Jay, Philippe, Blache, Philippe, Joubert, Dominique, Hollande, Frédéric

“…Tight junctions have recently emerged as essential signaling regulators of proliferation and differentiation in epithelial tissues. Here, we aimed to identify…”
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The Wnt Target Jagged-1 Mediates the Activation of Notch Signaling by Progastrin in Human Colorectal Cancer Cells by PANNEQUIN, Julie, BONNANS, Caroline, DELAUNAY, Nathalie, RYAN, Joanne, BOURGAUX, Jean-François, JOUBERT, Dominique, HOLLANDE, Frédéric

“…The Wnt and Notch signaling pathways are both abnormally activated in colorectal cancer (CRC). We recently showed that progastrin depletion inhibited Wnt…”
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Antibiotics inhibit sphere-forming ability in suspension culture by Relier, Sébastien, Yazdani, Laura, Ayad, Oualid, Choquet, Armelle, Bourgaux, Jean-François, Prudhomme, Michel, Pannequin, Julie, Macari, Françoise, David, Alexandre

“…This last decade, a lot of emphasis has been placed on developing new cancer cell culture models, closer to in vivo condition, in order to test new drugs and…”
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The Symplekin/ZONAB Complex Inhibits Intestinal Cell Differentiation by the Repression of AML1/Runx1 by Buchert, Michael, Darido, Charbel, Lagerqvist, Ebba, Sedello, Anna, Cazevieille, Chantal, Buchholz, Frank, Bourgaux, Jean–Francois, Pannequin, Julie, Joubert, Dominique, Hollande, Frédéric

“…Background & Aims Symplekin is a ubiquitously expressed protein involved in RNA polyadenylation and transcriptional regulation that localizes at tight…”
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