Search Results - "Panman, Matthijs"

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    Guanidinium-Induced Denaturation by Breaking of Salt Bridges by Meuzelaar, Heleen, Panman, Matthijs R., Woutersen, Sander

    Published in Angewandte Chemie International Edition (07-12-2015)
    “…Despite its wide use as a denaturant, the mechanism by which guanidinium (Gdm+) induces protein unfolding remains largely unclear. Herein, we show evidence…”
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    Accelerating the Shuttling in Hydrogen-Bonded Rotaxanes: Active Role of the Axle and the End Station by Kumpulainen, Tatu, Panman, Matthijs R, Bakker, Bert H, Hilbers, Michiel, Woutersen, Sander, Brouwer, Albert M

    Published in Journal of the American Chemical Society (04-12-2019)
    “…The relation between the chemical structure and the mechanical behavior of molecular machines is of paramount importance for a rational design of superior…”
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    On the (un)coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome by Takala, Heikki, Lehtivuori, Heli K., Berntsson, Oskar, Hughes, Ashley, Nanekar, Rahul, Niebling, Stephan, Panman, Matthijs, Henry, Léocadie, Menzel, Andreas, Westenhoff, Sebastian, Ihalainen, Janne A.

    Published in The Journal of biological chemistry (25-05-2018)
    “…Phytochromes are photoreceptors in plants, fungi, and various microorganisms and cycle between metastable red light–absorbing (Pr) and far-red light–absorbing…”
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    Unraveling VEALYL Amyloid Formation Using Advanced Vibrational Spectroscopy and Microscopy by Roeters, Steven J., Sawall, Mathias, Eskildsen, Carl E., Panman, Matthijs R., Tordai, Gergely, Koeman, Mike, Neymeyr, Klaus, Jansen, Jeroen, Smilde, Age K., Woutersen, Sander

    Published in Biophysical journal (07-07-2020)
    “…Intermediate species are hypothesized to play an important role in the toxicity of amyloid formation, a process associated with many diseases. This process can…”
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    Water lubricates hydrogen-bonded molecular machines by Panman, Matthijs R., Bakker, Bert H., den Uyl, David, Kay, Euan R., Leigh, David A., Buma, Wybren Jan, Brouwer, Albert M., Geenevasen, Jan A. J., Woutersen, Sander

    Published in Nature chemistry (01-11-2013)
    “…The mechanical behaviour of molecular machines differs greatly from that of their macroscopic counterparts. This applies particularly when considering concepts…”
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    Folding of a Zinc-Finger ββα-Motif Investigated Using Two-Dimensional and Time-Resolved Vibrational Spectroscopy by Meuzelaar, Heleen, Panman, Matthijs R, van Dijk, Chris N, Woutersen, Sander

    Published in The journal of physical chemistry. B (03-11-2016)
    “…Small proteins provide good model systems for studying the fundamental forces that control protein folding. Here, we investigate the folding dynamics of the…”
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    Operation Mechanism of a Molecular Machine Revealed Using Time-Resolved Vibrational Spectroscopy by Panman, Matthijs R, Bodis, Pavol, Shaw, Daniel J, Bakker, Bert H, Newton, Arthur C, Kay, Euan R, Brouwer, Albert M, Buma, Wybren Jan, Leigh, David A, Woutersen, Sander

    “…Rotaxanes comprise macrocycles that can shuttle between docking stations along an axle. We explored the nanosecond shuttling mechanism by reversing the…”
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    Transient two-dimensional vibrational spectroscopy of an operating molecular machine by Panman, Matthijs R., van Dijk, Chris N., Huerta-Viga, Adriana, Sanders, Hans J., Bakker, Bert H., Leigh, David A., Brouwer, Albert M., Buma, Wybren Jan, Woutersen, Sander

    Published in Nature communications (20-12-2017)
    “…Synthetic molecular machines are promising building blocks for future nanoscopic devices. However, the details of their mechanical behaviour are in many cases…”
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    Photoactivation of Drosophila melanogaster cryptochrome through sequential conformational transitions by Berntsson, Oskar, Rodriguez, Ryan, Henry, Léocadie, Panman, Matthijs R, Hughes, Ashley J, Einholz, Christopher, Weber, Stefan, Ihalainen, Janne A, Henning, Robert, Kosheleva, Irina, Schleicher, Erik, Westenhoff, Sebastian

    Published in Science advances (17-07-2019)
    “…Cryptochromes are blue-light photoreceptor proteins, which provide input to circadian clocks. The cryptochrome from ( Cry) modulates the degradation of…”
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    Amplifying vibrational circular dichroism by manipulation of the electronic manifold by Domingos, Sérgio R, Panman, Matthijs R, Bakker, Bert H, Hartl, Frantisek, Buma, Wybren J, Woutersen, Sander

    “…Vibrational circular dichroism is a powerful technique to study the stereochemistry of chiral molecules, but often suffers from small signal intensities…”
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