Search Results - "Pankras, C."

Effect of abiraterone acetate plus prednisone on the pharmacokinetics of dextromethorphan and theophylline in patients with metastatic castration-resistant prostate cancer by Chi, K. N., Tolcher, A., Lee, P., Rosen, P. J., Kollmannsberger, C. K., Papadopoulos, K. P., Patnaik, A., Molina, A., Jiao, J., Pankras, C., Kaiser, B., Bernard, A., Tran, N., Acharya, M.

“…Purpose To assess the effect of abiraterone acetate plus prednisone on the pharmacokinetics of dextromethorphan HBr (CYP2D6 substrate) and theophylline (CYP1A2…”
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Effect of abiraterone acetate plus prednisone on the QT interval in patients with metastatic castration-resistant prostate cancer by Tolcher, A. W., Chi, K. N., Shore, N. D., Pili, R., Molina, A., Acharya, M., Kheoh, T., Jiao, J. J., Gonzalez, M., Trinh, A., Pankras, C., Tran, N.

“…Purpose Abiraterone is the active metabolite of the pro-drug abiraterone acetate (AA) and a selective inhibitor of CYP17, a key enzyme in testosterone…”
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