Search Results - "Panknin, O"
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Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo
Published in Leukemia (01-10-2017)“…Neomorphic mutations in isocitrate dehydrogenase 1 ( IDH1 ) are frequently found in several human cancer types including acute myeloid leukemia (AML) and lead…”
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Asymmetric [2,3]-Sigmatropic Rearrangement of Allylic Ammonium Ylides
Published in Journal of the American Chemical Society (06-07-2005)“…An asymmetric Lewis acid-mediated [2,3]-sigmatropic rearrangement of allylic amines has been developed, affording the corresponding homoallylic amines in good…”
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Synthesis of New Sugar-Based Surfactants and Evaluation of Their Hemolytic Activities
Published in Journal of organic chemistry (28-04-2006)“…The synthesis of four sugar-based surfactants derived from glucose and (R)-12-hydroxystearic acid is described. The surfactants have a hydroxy group in the…”
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Proof of Principle in the Selective Treatment of Cancer by Antibody-Directed Enzyme Prodrug Therapy: The Development of a Highly Potent Prodrug
Published in Angewandte Chemie International Edition (01-03-2002)“…Perfectly adept for tumor treatment: With the seco‐CBI‐Q galactoside 1 a novel highly potent prodrug for the selective treatment of cancer using the ADEPT…”
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Proof of Principle in the Selective Treatment of Cancer by Antibody-Directed Enzyme Prodrug Therapy: The Development of a Highly Potent Prodrug
Published in Angewandte Chemie (01-03-2002)“…Ein vielversprechender Ansatz für die Tumortherapie: Mit dem seco‐CBI‐Q‐Galactosid 1 wurde ein neues hochwirksames Prodrug für eine selektive Tumortherapie…”
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