Search Results - "Paniagua, Marina"
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Therapeutic Effect of Human Adipose Tissue‐Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage
Published in Stem cells (Dayton, Ohio) (01-10-2017)“…Limbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche…”
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A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency
Published in Translational research : the journal of laboratory and clinical medicine (01-04-2019)“…Ocular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive…”
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Advanced Therapy and Clinical Trials to Treat Patients with Optic Nerve Diseases
Published in Neurotoxicity research (01-12-2022)“…Optic nerve diseases include a wide variety of pathogenic conditions triggering injury or dysfunction of the optic nerves that lead to visual impairment or…”
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Subconjunctival injection of mesenchymal stem cells for corneal failure due to limbal stem cell deficiency: state of the art
Published in Stem cell research & therapy (13-01-2021)“…Mesenchymal stem cells (MSCs) have unique and beneficial properties and are currently used to treat a broad variety of diseases. These properties include the…”
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Poly-l/dl-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells
Published in Colloids and surfaces, B, Biointerfaces (01-05-2019)“…[Display omitted] •Limbal epithelial cell transplantation onto the ocular surface requires a substratum.•Polylactic acid (PLA) films can be functionalized with…”
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Intravitreal allogeneic mesenchymal stem cells: a non-randomized phase II clinical trial for acute non-arteritic optic neuropathy
Published in Stem cell research & therapy (21-09-2023)“…Background An effective treatment for acute non-arteritic ischemic optic neuropathy (NA-AION) has not been known or proven yet. Previous studies have suggested…”
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Frequency and phenotype of headache in covid-19: a study of 2194 patients
Published in Scientific reports (19-07-2021)“…To estimate the frequency of headache in patients with confirmed COVID-19 and characterize the phenotype of headache attributed to COVID-19, comparing patients…”
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Advanced Therapy Medicinal Products for the Eye: Definitions and Regulatory Framework
Published in Pharmaceutics (06-03-2021)“…Advanced therapy medicinal products (ATMPs) are a group of innovative and complex biological products for human use that comprises somatic cell therapy…”
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Goals and Challenges of Stem Cell-Based Therapy for Corneal Blindness Due to Limbal Deficiency
Published in Pharmaceutics (16-09-2021)“…Corneal failure is a highly prevalent cause of blindness. One special cause of corneal failure occurs due to malfunction or destruction of the limbal stem cell…”
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Corneal Regeneration Using Adipose-Derived Mesenchymal Stem Cells
Published in Cells (Basel, Switzerland) (01-08-2022)“…Adipose-derived stem cells are a subtype of mesenchymal stem cell that offers the important advantage of being easily obtained (in an autologous manner) from…”
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In Vivo Confocal Microscopy in Limbal Stem Cell Deficiency After Mesenchymal Stem Cell Transplantation: A Sub-analysis from a Phase I–II Clinical Trial
Published in Ophthalmology and therapy (01-12-2023)“…Introduction The aim of this work is to evaluate the effect of mesenchymal stem cell transplantation (MSCT) and cultivated limbal epithelial transplantation…”
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Optimization of Human Limbal Stem Cell Culture by Replating a Single Limbal Explant
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Cultured limbal epithelial stem cell transplantation is a clinical procedure used to regenerate the corneal epithelium in patients with limbal stem cell…”
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Comparison of functional limbal epithelial stem cell isolation methods
Published in Experimental eye research (01-05-2016)“…The transplantation of limbal epithelial stem cells (LESCs) cultured in vitro is a great advance in the treatment of patients suffering from LESC deficiency…”
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Chitosan–gelatin biopolymers as carrier substrata for limbal epithelial stem cells
Published in Journal of materials science. Materials in medicine (01-12-2013)“…The aim of this work was to evaluate semi-synthetic biopolymers based on chitosan (CH) and gelatin (G) as potential in vitro carrier substrata for human limbal…”
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Successful Consecutive Expansion of Limbal Explants Using a Biosafe Culture Medium under Feeder Layer-Free Conditions
Published in Current eye research (04-05-2017)“…Purpose: Transplantation of in vitro cultured limbal epithelial stem cells (LESCs) is a treatment widely used for LESC deficiency. However, the number of…”
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Neuroprotection in ophthalmology. Targets in the most frequent diseases. A clinician's point of view
Published in Acta ophthalmologica (Oxford, England) (01-12-2022)“…Objectives: To briefly review the most frequent ocular diseases in which a neuroprotective treatment would be needed and to present the results of a…”
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Consecutive Expansion of Limbal Epithelial Stem Cells from a Single Limbal Biopsy
Published in Current eye research (01-05-2013)“…Abstract Purpose: Corneal epithelium is maintained by limbal epithelial stem cells (LESCs), the loss of which can be catastrophic for corneal transparency…”
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A comparison of stem cell-related gene expression in the progenitor-rich limbal epithelium and the differentiating central corneal epithelium
Published in Molecular vision (2011)“…Corneal epithelium is maintained by a population of stem cells (SCs) that have not been identified by specific molecular markers. The objective of this study…”
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El demonio y sus formas en la hagiografía quiteña de Mariana de Jesús Torres
Published in Hipogrifo (New York, NY) (01-06-2022)“…This study deals with an author who has had little relevance in the literature of Quito as her work did not become well-known until the 20th century and is…”
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Cuidado urgente del paciente con quemaduras por inhalación: una revisión bibliográfica
Published in Nure investigación (01-05-2020)“…Introduction: Inhalation burns are usually associated with other burns. Burns become an important risk factor that increases the morbi-mortality of those who…”
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