Search Results - "Pangborn, W"

The Conducting Form of Gramicidin A is a Right-Handed Double-Stranded Double Helix by Burkhart, B. M., Li, N., Langs, D. A., Pangborn, W. A., Duax, W. L.

“…The linear pentadecapeptide antibiotic, gramicidin D, is a naturally occurring product of Bacillus brevis known to form ion channels in synthetic and natural…”
Get full text

Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis by Galitsky, Nikolai, Cody, Vivian, Wojtczak, Andrzej, Ghosh, Debashis, Luft, Joseph R., Pangborn, Walter, English, Leigh

“…The coleopteran‐active δ‐endotoxin Cry3Bb1 from Bacillus thuringiensis (Bt) strain EG7231 is uniquely toxic to Diabrotica undecimpunctata, the Southern corn…”
Get full text

Structure of gramicidin D-RbCl complex at atomic resolution from low-temperature synchrotron data: interactions of double-stranded gramicidin channel contents and cations with channel wall by Główka, M. L., Olczak, A., Bojarska, J., Szczesio, M., Duax, W. L., Burkhart, B. M., Pangborn, W. A., Langs, D. A., Wawrzak, Z.

“…Gramicidin D (gD) is a naturally occurring ionophoric antibiotic that forms membrane channels specific for monovalent cations. The crystal structure of the…”
Get full text

Methotrexate-resistant variants of human dihydrofolate reductase. Effects of Phe31 substitutions by CHUNDURU, S. K, CODY, V, LUFT, J. R, PANGBORN, W, APPLEMAN, J. R, BLAKLEY, R. L

“…Substitution of glycine or alanine for phenylalanine 31 in human dihydrofolate reductase produces variants that are inhibited less by methotrexate (MTX) than…”
Get full text

Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 Å resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites by Wojtczak, Andrzej, Cody, Vivian, Luft, Joseph R., Pangborn, Walter

“…The first observation of the unique environment for thyroxine (T4) binding in tetrameric rat transthyretin (rTTR) is reported as determined by X‐ray…”
Get full text

A novel complex of a phenolic derivative with insulin: Structural features related to the T → R transition by Smith, G.David, Ciszak, Ewa, Pangborn, Walter

“…The structure of a symmetric T3Rf3 insulin hexamer, complexed with 4‐hydroxybenzamide, has been determined using X‐ray crystallographic techniques. Data were…”
Get full text

R6 hexameric insulin complexed with m-cresol or resorcinol by Smith, G. David, Ciszak, Ewa, Magrum, Lucy A., Pangborn, Walter A., Blessing, Robert H.

“…The structures of three R6 human insulin hexamers have been determined. Crystals of monoclinic m‐cresol–insulin, monoclinic resorcinol–insulin and rhombohedral…”
Get full text

Crystallization and preliminary X-ray diffraction analysis of the complex of human placental 17 beta-hydroxysteroid dehydrogenase with NADP by Zhu, D W, Lee, X, Breton, R, Ghosh, D, Pangborn, W, Daux, W L, Lin, S X

“…Single crystals of human placental 17 beta-hydroxysteroid dehydrogenase, an enzyme that plays an important role in the interconversion of estrogens, were…”
Get more information

Gramicidin D conformation, dynamics and membrane ion transport by Burkhart, Brian M., Gassman, Ryan M., Langs, David A., Pangborn, Walter A., Duax, William L., Pletnev, Vladimir

“…The linear pentadecapeptide antibiotic, gramicidin D, a heterogeneous mixture of six components, is a naturally occurring product of Bacillus brevis known to…”
Get full text

Studies on the mechanism of membrane fusion: evidence for an intermembrane Ca2+-phospholipid complex, synergism with Mg2+, and inhibition by spectrin by Portis, A, Newton, C, Pangborn, W, Papahadjopoulos, D

“…The interaction of Ca2+ and Mg2+ with phosphatidylserine (PS) vesicles in 0.1 M NaCl aqueous solution was studied by equilibrium dialysis binding, X-ray…”
Get full text

Studies on the three-dimensional structure of estrogenic 17 beta-hydroxysteroid dehydrogenase by Lin, S X, Zhu, D W, Azzi, A, Campbell, R L, Breton, R, Labrie, F, Ghosh, D, Pletnev, V, Duax, W L, Pangborn, W

“…The structure-function relationship of the estrogenic 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD1), a pivotal enzyme in the synthesis of active sex…”
Get more information

Heterodimer Formation and Crystal Nucleation of Gramicidin D by Burkhart, Brian M., Gassman, Ryan M., Langs, David A., Pangborn, Walter A., Duax, William L.

“…The linear pentadecapeptide antibiotic gramicidin D is a heterogeneous mixture of six components. Precise refinements of three-dimensional structures of…”
Get full text

Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH by Cody, Vivian, Luft, Joe R., Pangborn, Walt

“…Structural data are reported to 2.5 Å resolution for the first full analysis of the methotrexate‐resistant Leu22Arg (L22R) variant of mouse dihydrofolate…”
Get full text

Molecular Interactions in Binary Solids: Crystal Structure of a Cholesteryl Ester Solid Solution by Dorset, Douglas L., Pangborn, Walter A.

“…The x-ray crystal structure analysis of a cholesteryl ester solid solution, cholesteryl undecanoate/cholesteryl laurate in a molar ratio 0.52/0.48, is…”
Get full text

Structural determination and packing analysis of a cholesteryl caprate/cholesteryl laurate solid solution by McCourt, M P, Strong, P, Pangborn, W, Dorset, D L

“…This paper describes the X-ray crystal structure analysis of a cholesteryl ester solid solution, cholesteryl decanoate/cholesteryl laurate, grown from a bulk…”
Get full text

X-ray crystal structure of cytotoxic oxidized cholesterols: 7-ketocholesterol and 25-hydroxycholesterol by McCourt, M.P. (Hauptman Woodward Medical Research Institute, Buffalo, NY.), Ashraf, K, Miller, R, Weeks, C.M, Li, N, Pangborn, W, Dorset, D.L

“…The cytotoxic cholesterol derivative, 7-ketocholesterol, crystallizes in a monoclinic unit cell, space group P2(1) with a 11.405 angstroms, b = 6.288…”
Get full text

Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate by Cody, V, Galitsky, N, Luft, J R, Pangborn, W, Gangjee, A, Devraj, R, Queener, S F, Blakley, R L

“…The novel furopyrimidine N-(4-{N-[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]methylamino}benzoyl)-L- glutamate (MTXO), a classical antifolate with antitumor…”
Get full text

A thyrotropin-releasing hormone analogue: pGlu-Phe-D-Pro-psi [CN4]-NMe at 293 and 107 K by Howell, P L, Pangborn, W A, Marshall, G R, Zabrocki, J, Smith, G D

“…Data have been measured at two temperatures, 293 K and 107 K, for a crystal of a thyrotropin-releasing hormone analogue, pGlu-Phe-D-Pro-psi [CN4]-NMe,…”
Get more information

Molecular mechanism of inhibition of steroid dehydrogenases by licorice-derived steroid analogs in modulation of steroid receptor function by Ghosh, D, Wawrzak, Z, Pletnev, V, Erman, M, Duax, W L, Pangborn, W, Zhu, D W, Labrie, F, Lin, S X

Get more information

Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association by Hernandez-Guzman, Francisco G, Higashiyama, Tadayoshi, Pangborn, Walter, Osawa, Yoshio, Ghosh, Debashis

“…Estrone sulfatase (ES; 562 amino acids), one of the key enzymes responsible for maintaining high levels of estrogens in breast tumor cells, is associated with…”
Get full text