Search Results - "Pang, P. S."

Persistent pulmonary congestion before discharge predicts rehospitalization in heart failure: a lung ultrasound study by Gargani, Luna, Pang, P S, Frassi, F, Miglioranza, M H, Dini, F L, Landi, P, Picano, E

“…B-lines evaluated by lung ultrasound (LUS) are the sonographic sign of pulmonary congestion, a major predictor of morbidity and mortality in patients with…”
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Structures and properties of energetic cations in energetic salts by Liu, W, Liu, W. L, Pang, S. P

“…Energetic salts provide many advantages over conventional energetic molecular compounds. Their high densities, high heats of formation and low vapor pressures…”
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Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART by Corley, Michael J, Sacdalan, Carlo, Pang, Alina P S, Chomchey, Nitiya, Ratnaratorn, Nisakorn, Valcour, Victor, Kroon, Eugene, Cho, Kyu S, Belden, Andrew C, Colby, Donn, Robb, Merlin, Hsu, Denise, Spudich, Serena, Paul, Robert, Vasan, Sandhya, Ndhlovu, Lishomwa C

“…HIV-1 disrupts the host epigenetic landscape with consequences for disease pathogenesis, viral persistence, and HIV-associated comorbidities. Here, we examined…”
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Disconnect between the effects of serelaxin on renal function and outcome in acute heart failure by Beldhuis, I. E., ter Maaten, J. M., Figarska, S. M., Damman, K., Pang, P. S., Greenberg, B., Davison, B. A., Cotter, G., Severin, T., Gimpelewicz, C., Felker, G. M., Filippatos, G., Teerlink, J. R., Metra, M., Voors, A. A.

“…Background We aimed to study whether improvement in renal function by serelaxin in patients who were hospitalized for acute heart failure (HF) might explain…”
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Epigenetic Delay in the Neurodevelopmental Trajectory of DNA Methylation States in Autism Spectrum Disorders by Corley, Michael J, Vargas-Maya, Nauru, Pang, Alina P S, Lum-Jones, Annette, Li, Dongmei, Khadka, Vedbar, Sultana, Razvan, Blanchard, D Caroline, Maunakea, Alika K

“…Autism spectrum disorders (ASD) are hypothesized to originate from perturbations in neural stem cell niche regions of the developing brain. Dynamic epigenetic…”
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The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells by Fujimoto, Brent A, Young, Madison, Carter, Lamar, Pang, Alina P S, Corley, Michael J, Fogelgren, Ben, Polgar, Noemi

“…Skeletal muscle handles ~80-90% of the insulin-induced glucose uptake. In skeletal muscle, insulin binding to its cell surface receptor triggers redistribution…”
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Retro‐age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements by Ndhlovu, Lishomwa C., Bendall, Matthew L., Dwaraka, Varun, Pang, Alina P. S., Dopkins, Nicholas, Carreras, Natalia, Smith, Ryan, Nixon, Douglas F., Corley, Michael J.

“…Reactivation of retroelements in the human genome has been linked to aging. However, whether the epigenetic state of specific retroelements can predict…”
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The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding by Pang, Phillip S., Jankowsky, Eckhard, Planet, Paul J., Pyle, Anna Marie

“…The RNA helicase/protease NS3 plays a central role in the RNA replication of hepatitis C virus (HCV), a cytoplasmic RNA virus that represents a major worldwide…”
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Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination by Pang, Alina P S, Higgins-Chen, Albert T, Comite, Florence, Raica, Ioana, Arboleda, Christopher, Went, Hannah, Mendez, Tavis, Schotsaert, Michael, Dwaraka, Varun, Smith, Ryan, Levine, Morgan E, Ndhlovu, Lishomwa C, Corley, Michael J

“…The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence suggest that severe COVID-19 is associated with durable scars to the…”
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Increased adiposity in DNA binding-dependent androgen receptor knockout male mice associated with decreased voluntary activity and not insulin resistance by Rana, Kesha, Fam, Barbara C, Clarke, Michele V, Pang, Tammy P S, Zajac, Jeffrey D, MacLean, Helen E

“…In men, as testosterone levels decrease, fat mass increases and muscle mass decreases. Increased fat mass in men, in particular central obesity, is a major…”
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Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound by Corley, Michael J., Pang, Alina P.S., Rasmussen, Thomas A., Tolstrup, Martin, Søgaard, Ole S., Ndhlovu, Lishomwa C.

“…This study aimed to identify candidate host epigenetic biomarkers predicting latency reversal agents (LRA) efficacy and HIV-1 rebound kinetics during…”
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The current and future management of acute heart failure syndromes by Pang, Peter S., Komajda, Michel, Gheorghiade, Mihai

“…Hospitalization for heart failure (HF) marks a substantial crossroad for patients, as greater than one-third will be re-hospitalized or dead within 90 days…”
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Identification of gene pathways altered by deletion of the androgen receptor specifically in mineralizing osteoblasts and osteocytes in mice by Russell, Patricia K, Clarke, Michele V, Skinner, Jarrod P, Pang, Tammy P S, Zajac, Jeffrey D, Davey, Rachel A

“…Androgens play a key role in skeletal growth and maintenance in males and can mediate their actions, at least in part, via the androgen receptor (AR) in…”
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Changes in renal function during hospitalization and soon after discharge in patients admitted for worsening heart failure in the placebo group of the EVEREST trial by Blair, John E.A., Pang, Peter S., Schrier, Robert W., Metra, Marco, Traver, Brian, Cook, Thomas, Campia, Umberto, Ambrosy, Andrew, Burnett, John C., Grinfeld, Liliana, Maggioni, Aldo P., Swedberg, Karl, Udelson, James E., Zannad, Faiez, Konstam, Marvin A., Gheorghiade, Mihai

“…Aim To provide an in-depth clinical characterization and analysis of outcomes of the patients hospitalized for heart failure (HF) who subsequently develop…”
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Once daily ledipasvir/sofosbuvir fixed-dose combination with ribavirin in patients with inherited bleeding disorders and hepatitis C genotype 1 infection by Stedman, C. A. M., Hyland, R. H., Ding, X., Pang, P. S., McHutchison, J. G., Gane, E. J.

“…Aim People with inherited bleeding disorders have been disproportionally affected by HCV. We assessed the fixed‐dose combination of the NS5A inhibitor…”
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Genome‐wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID‐19 by Corley, Michael J., Pang, Alina P.S., Dody, Kush, Mudd, Philip A., Patterson, Bruce K., Seethamraju, Harish, Bram, Yaron, Peluso, Michael J., Torres, Leonel, Iyer, Nikita S., Premeaux, Thomas A., Yeung, Stephen T., Chandar, Vasuretha, Borczuk, Alain, Schwartz, Robert E., Henrich, Timothy J., Deeks, Steven G., Sacha, Jonah B., Ndhlovu, Lishomwa C.

“…The global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a highly pathogenic RNA virus causing coronavirus disease…”
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A physiological role for androgen actions in the absence of androgen receptor DNA binding activity by Pang, Tammy P.S., Clarke, Michele V., Ghasem-Zadeh, Ali, Lee, Nicole K.L., Davey, Rachel A., MacLean, Helen E.

“…► We investigate non-DNA binding dependent (DBD) androgen receptor (AR) actions. ► AR from male mice with deletion of the 2nd zinc finger of the DBD (AR ΔZF2)…”
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Effects of tolvaptan on dyspnoea relief from the EVEREST trials by Pang, Peter S., Konstam, Marvin A., Krasa, Holly B., Swedberg, Karl, Zannad, Faiez, Blair, John E.A., Zimmer, Christopher, Teerlink, John R., Maggioni, Aldo P., Burnett, John C., Grinfeld, Liliana, Ouyang, John, Udelson, James E., Gheorghiade, Mihai

“…Aims To describe the effects of tolvaptan therapy on dyspnoea relief based on timing of delivery, influence of concomitant therapies, and baseline patient and…”
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Caspases and therapeutic potential of caspase inhibitors in moderate–severe SARS‐CoV‐2 infection and long COVID by Plassmeyer, Matthew, Alpan, Oral, Corley, Michael J., Premeaux, Thomas A., Lillard, Kimberleigh, Coatney, Paige, Vaziri, Tina, Michalsky, Suzan, Pang, Alina P. S., Bukhari, Zaheer, Yeung, Stephen T., Evering, Teresa H., Naughton, Gail, Latterich, Martin, Mudd, Philip, Spada, Alfred, Rindone, Nicole, Loizou, Denise, Ulrik Sønder, Søren, Ndhlovu, Lishomwa C., Gupta, Raavi

“…Background COVID‐19 can present with lymphopenia and extraordinary complex multiorgan pathologies that can trigger long‐term sequela. Aims Given that…”
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Cell‐type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV by Corley, Michael J., Pang, Alina P. S., Shikuma, Cecilia M., Ndhlovu, Lishomwa C.

“…The anti‐diabetic drug metformin may promote healthy aging. However, few clinical trials of metformin assessing biomarkers of aging have been completed. In…”
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