Search Results - "Pang, Jiaohui"

Comprehensive profiling of EGFR mutation subtypes reveals genomic-clinical associations in non-small-cell lung cancer patients on first-generation EGFR inhibitors by Bai, Yongkang, Liu, Xiang, Zheng, Limin, Wang, Song, Zhang, Junli, Xiong, Shi, Zhang, Pengfei, Jiao, Zichen, Zhao, Gefei, Zhou, Chu, Pang, Jiaohui, Xu, Yang, Ou, Qiuxiang, Mao, Yuan, Zhang, Louqian

“…Common sensitizing mutations in epidermal growth factor receptor (cEGFR), including exon 19 deletions (19-Del) and exon 21 L858R substitution, are associated…”
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The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification by Yang, Yefan, Ding, Ying, Gong, Yuxi, Zhao, Sha, Li, Mingna, Li, Xiao, Song, Guoxin, Zhai, Boya, Liu, Jin, Shao, Yang, Zhu, Liuqing, Pang, Jiaohui, Ma, Yutong, Ou, Qiuxiang, Wu, Xue, Zhang, Zhihong

“…Pancreatic ductal adenocarcinoma (PDAC) is the major subtype of pancreatic cancer and head PDACs show distinct characteristics from body/tail PDACs. With…”
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Genomic profiling, prognosis, and potential interventional targets in young and old patients with cholangiocarcinoma by Wang, Junhua, Shi, Yaoting, Chen, Jianbo, Liu, Juying, Zhao, Xiaotian, Pang, Jiaohui, Sun, Ximin, Tian, Yichen, Ou, Qiuxiang, Xia, Feng, Chen, Yunjie

“…Molecular mechanisms behind potentially inferior prognosis of old cholangiocarcinoma (CCA) patients are unclear. Prevalence of interventional targets and the…”
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Mutations in the MET tyrosine kinase domain and resistance to tyrosine kinase inhibitors in non-small-cell lung cancer by Yao, Yu, Yang, Huaping, Zhu, Bo, Wang, Song, Pang, Jiaohui, Wu, Xiaoying, Xu, Yang, Zhang, Junli, Zhang, Jinfeng, Ou, Qiuxiang, Tian, Hui, Zhao, Zheng

“…The Mesenchymal epithelial transition factor (MET) gene encodes a receptor tyrosine kinase with pleiotropic functions in cancer. MET exon 14 skipping…”
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Identification of pathogenic germline variants in a large Chinese lung cancer cohort by clinical sequencing by Yu, Zhe, Zhang, Zirui, Liu, Jun, Wu, Xiaoying, Fan, Xiaojun, Pang, Jiaohui, Bao, Hua, Yin, Jiani, Wu, Xue, Shao, Yang, Liu, Zhengcheng, Liu, Fang

“…Genetic factors play significant roles in the tumorigenicity of lung cancer; however, there is lack of systematic and large‐scale characterization of…”
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Comprehensive genomic and clinical analyses identify APOBEC mutational signatures as a brain metastasis risk factor in lung adenocarcinoma patients by Li, Qiang, Jiang, Meng, Hong, Shiqiang, Yang, Jing, Wu, Xiaoying, Pang, Jiaohui, Chen, Yedan, Zhao, Xiaotian, Ding, Xiao

“…•APOBEC mutational signatures- new brain metastasis risk factor in lung adenocarcinoma.•Age≤60 years and EGFR mutation screened as the other 2 brain metastasis…”
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Recurrence/prognosis estimation using a molecularly positive surgical margin‐based model calls for alternative curative strategies in pIIIA/N2 NSCLC by Li, Li, He, Kewen, Zhou, Tao, Xu, Yang, Pang, Jiaohui, Yu, Qingxi, Gao, Yongsheng, Shi, Hongjin, Zhu, He, Li, Mengke, Yu, Jinming, Yuan, Shuanghu

“…Stage pIIIA/N2 non‐small cell lung cancer (NSCLC) is primarily treated by complete surgical resection combined with neoadjuvant/adjuvant therapies. However, up…”
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Comprehensive genomic profiling of pulmonary spindle cell carcinoma using tissue and plasma samples: insights from a real‐world cohort analysis by Sun, Yi, Qin, Shilei, Wang, Song, Pang, Jiaohui, Ou, Qiuxiang, Liang, Weiquan, Zhong, Hai

“…Pulmonary spindle cell carcinoma (PSCC) is a rare and aggressive non‐small cell lung cancer (NSCLC) subtype with a dismal prognosis. The molecular…”
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Pathway-Based Analysis Revealed the Role of Keap1-Nrf2 Pathway and PI3K-Akt Pathway in Chinese Esophageal Squamous Cell Carcinoma Patients With Definitive Chemoradiotherapy by Dai, Honghai, Wei, Yanjun, Liu, Yunxia, Liu, Jingwen, Yu, Ruoying, Zhang, Junli, Pang, Jiaohui, Shao, Yang, Li, Qiang, Yang, Zhe

“…Esophageal squamous cell carcinoma (ESCC) is the major type of EC in China. Chemoradiotherapy is a standard definitive treatment for early-stage EC and…”
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Lineage tracing for multiple lung cancer by spatiotemporal heterogeneity using a multi-omics analysis method integrating genomic, transcriptomic, and immune-related features by Song, Yijun, Zhou, Jiebai, Zhao, Xiaotian, Zhang, Yong, Xu, Xiaobo, Zhang, Donghui, Pang, Jiaohui, Bao, Hairong, Ji, Yuan, Zhan, Mengna, Wang, Yulin, Ou, Qiuxiang, Hu, Jie

“…Introduction The distinction between multiple primary lung cancer (MPLC) and intrapulmonary metastasis (IPM) holds clinical significance in staging,…”
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P065: The clinical utility of plasma circulating tumor DNA in the diagnosis and disease surveillance in non-DLBCL non-Hodgkin’s lymphomas by Zhu, Minyi, Zhao, Xiaotian, Xiao, Yao, Pang, Jiaohui, Zhu, Liuqing, Yu, Ruoying, Ou, Qiuxiang

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Comprehensive genomic analysis of early and late-onset hepatocellular carcinoma by Yang, Jialin, Chen, Chao, Wang, Song, Zhang, Yaru, Pang, Jiaohui, Wang, Yajun, Ou, Qiuxiang, Jiang, Hao, Liu, Juying

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YAP1 amplification as a prognostic factor of definitive chemoradiotherapy in nonsurgical esophageal squamous cell carcinoma by Dai, Honghai, Shao, Yang W., Tong, Xiaoling, Wu, Xue, Pang, Jiaohui, Feng, Alei, Yang, Zhe

“…Background Definitive chemoradiation therapy (dCRT) is the standard treatment for patients with nonsurgical esophageal squamous cell carcinoma (ESCC), yet…”
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Genomic Profiling Reveals Novel Predictive Biomarkers for Chemo-Radiotherapy Efficacy and Thoracic Toxicity in Non-Small-Cell Lung Cancer by He, Kewen, Zhang, Shaotong, Pang, Jiaohui, Yin, Jiani C., Mu, Dianbin, Wang, Jun, Ge, Hong, Ma, Jie, Yang, Zhe, Zheng, Xiaoli, Dong, Lihua, Zhang, Junli, Chang, Pengyu, Li, Li, Tang, Shanshan, Bao, Hua, Wu, Xue, Wang, Xiaonan, Shao, Yang, Yu, Jinming, Yuan, Shuanghu

“…Chemo-radiotherapy (CRT) remains the main treatment modality for non-small-cell lung cancer (NSCLC). However, its clinical efficacy is largely limited by…”
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Predictive value of DOT1L mutations for clinical outcomes in non‐small‐cell lung cancer patients receiving immune checkpoint inhibitor therapy by Guo, Tianxing, Wang, Zhaofeng, Wang, Song, Zhang, Yaru, Pang, Jiaohui, Ying, Yajun, Ou, Qiuxiang, Shen, Dong, Li, Gang

“…Dear Editor, In this study, we present findings that highlight the role of baseline Disruptor of telomeric silencing 1-like (DOT1L) mutations as a promising…”
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Early postoperative plasma circulating tumour DNA for molecular residue disease detection and recurrence risk evaluation in surgical non‐small cell lung cancer by Tang, Jie, Tian, Yingsong, Wang, Song, Liu, Yong, Chen, Manjun, Yang, Xudong, Tong, Xinghe, Wang, Mengtian, Zhao, Yunping, Pang, Jiaohui, Ou, Qiuxiang, Chen, Xiaobo

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Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers by Ying, Jieer, Yang, Lin, Yin, Jiani C, Xia, Guojie, Xing, Minyan, Chen, Xiaoxi, Pang, Jiaohui, Wu, Yong, Bao, Hua, Wu, Xue, Shao, Yang, Zhu, Lingjun, Cheng, Xiangdong

“…BackgroundDefects in replication repair-associated DNA polymerases often manifest an ultra-high tumor mutational burden (TMB), which is associated with higher…”
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Molecular risk factors for locoregional recurrence in resected non‐small cell lung cancer by Guo, Wei, Zhang, Tao, Li, Runze, Chen, Xiaoxi, Pang, Jiaohui, Bao, Hua, Wu, Xue, Shao, Yang, Qiu, Bin, Gao, Shugeng, He, Jie

“…Background Locoregional recurrence is of high risk and is associated with a poor prognosis in terms of OS for non‐small cell lung cancer (NSCLC). Local control…”
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Genomic features, evolutionary patterns and minimal residual disease at surgical margins as novel prognostic/predictive biomarkers in locally advanced rectal cancer by He, Kewen, Li, Li, Li, Aijie, Xu, Yang, Pang, Jiaohui, Mu, Dianbin, Ma, Jie, Ge, Hong, Maleki, Aurian, Qin, Xueting, Zhang, Xian, Ou, Qiuxiang, Shao, Yang, Yu, Jinming, Yuan, Shuanghu

“…Dear Editor, Locally advanced rectal cancers (LARCs) are characterized by stage II/III diseases and account for about 15% of colorectal cancer cases.1…”
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Clonal dynamics and Stereo-seq resolve origin and phenotypic plasticity of adenosquamous carcinoma by Zhao, Ruiying, Xu, Yunhua, Chen, Yedan, Zhang, Jiajun, Teng, Fei, Liao, Sha, Chen, Shengnan, Wu, Qian, Xiang, Chan, Pang, Jiaohui, Shang, Zhanxian, Zhao, Jikai, Bao, Hairong, Bao, Hua, Shao, Yang, Lu, Shun, Han, Yuchen

“…The genomic origin and development of the biphasic lung adenosquamous carcinoma (ASC) remain inconclusive. Here, we derived potential evolutionary trajectory…”
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