Search Results - "Pang, Jesse"

Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma by Kang, Wei, Tong, Joanna H M, Lung, Raymond W M, Dong, Yujuan, Zhao, Junhong, Liang, Qiaoyi, Zhang, Li, Pan, Yi, Yang, Weiqin, Pang, Jesse C S, Cheng, Alfred S L, Yu, Jun, To, Ka Fai

“…MicroRNAs (miRNAs) have been reported to play an important role in tumorigenesis. In this study, the role of miR-15a and miR-16-1 in gastric adenocarcinoma…”
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EBV‐encoded miRNAs target ATM‐mediated response in nasopharyngeal carcinoma by Lung, Raymond W‐M, Hau, Pok‐Man, Yu, Ken H‐O, Yip, Kevin Y, Tong, Joanna H‐M, Chak, Wing‐Po, Chan, Anthony W‐H, Lam, Ka‐Hei, Lo, Angela Kwok‐Fung, Tin, Edith K‐Y, Chau, Shuk‐Ling, Pang, Jesse C‐S, Kwan, Johnny S‐H, Busson, Pierre, Young, Lawrence S, Yap, Lee‐Fah, Tsao, Sai‐Wah, To, Ka‐Fai, Lo, Kwok‐Wai

“…Nasopharyngeal carcinoma (NPC) is a highly invasive epithelial malignancy that is prevalent in southern China and Southeast Asia. It is consistently associated…”
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MiR-383 is Downregulated in Medulloblastoma and Targets Peroxiredoxin 3 (PRDX3) by Li, Kay Ka-Wai, Pang, Jesse Chung-Sean, Lau, Kin-Mang, Zhou, Liangfu, Mao, Ying, Wang, Yin, Poon, Wai-Sang, Ng, Ho-Keung

“…Accumulating evidence suggests that microRNAs (miRNAs) are over‐ or under‐expressed in tumors, and abnormalities in miRNA expression may contribute to…”
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miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis by Kang, Wei, Huang, Tingting, Zhou, Yuhang, Zhang, Jinglin, Lung, Raymond W. M., Tong, Joanna H. M., Chan, Anthony W. H., Zhang, Bin, Wong, Chi Chun, Wu, Feng, Dong, Yujuan, Wang, Shiyan, Yang, Weiqin, Pan, Yi, Chak, Wing Po, Cheung, Alvin H. K., Pang, Jesse C. S., Yu, Jun, Cheng, Alfred S. L., To, Ka Fai

“…miR-375 is a tumor-suppressive microRNA (miRNA) in gastric cancer (GC). However, its molecular mechanism remains unclear. The aim of this study is to…”
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TGM2 inhibition attenuates ID1 expression in CD44-high glioma-initiating cells by Fu, Jun, Yang, Qun-ying, Sai, Ke, Chen, Fu-rong, Pang, Jesse C S, Ng, Ho-keung, Kwan, Aij-lie, Chen, Zhong-ping

“…CD44 is a molecular marker associated with cancer stem cell populations and treatment resistance in glioma. More effective therapies will result from…”
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miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1 by Li, Kay Ka Wai, MPhil, Pang, Jesse Chung-sean, MSc, Ching, Arthur Ka-keung, PhD, Wong, Chun Kwok, PhD, Kong, Xiangyin, PhD, Wang, Yin, MD, Zhou, Liangfu, MD, Chen, Zhongping, MD, Ng, Ho-keung, MD

“…Summary Given that miR-124 is preferentially expressed in differentiating and mature neurons and external granule cells of cerebellum are thought to be…”
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Clinical significance of vasculogenic mimicry in human gliomas by Liu, Xiao-mei, Zhang, Qing-ping, Mu, Yong-gao, Zhang, Xiang-hen, Sai, Ke, Pang, Jesse Chung-Sean, Ng, Ho-Keung, Chen, Zhong-ping

“…Vasculogenic mimicry (VM) is known as non-endothelial tumor cell-lined microvascular channels in aggressive tumors. We have previously found the presence of VM…”
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Oncogenic role of microRNAs in brain tumors by Pang, Jesse Chung-sean, Kwok, Wai Kei, Chen, Zhongping, Ng, Ho-Keung

“…MicroRNAs (miRNAs) are short non-protein-coding RNAs that function as key regulators of diverse biological processes through negative control on gene…”
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Overexpression of HMGA1 deregulates tumor growth via cdc25A and alters migration/invasion through a cdc25A-independent pathway in medulloblastoma by Lau, Kin-Mang, Chan, Queeny Kwan Yi, Pang, Jesse C. S., Ma, Fanny Man-Ting, Li, Kay K. W., Yeung, Walter Wai, Cheng, Alfred S. L., Feng, Hai, Chung, Nellie Y. F., Li, Hiu-Ming, Zhou, Liangfu, Wang, Yin, Mao, Ying, Ng, Ho-Keung

“…Overexpression of high mobility group AT-hook 1 (HMGA1) is common in human cancers. Little is known about the mechanisms underlying its deregulation and…”
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Mutation analysis of IDH1 in paired gliomas revealed IDH1 mutation was not associated with malignant progression but predicted longer survival by Yao, Yu, Chan, Aden Ka-Yin, Qin, Zhi Yong, Chen, Ling Chao, Zhang, Xin, Pang, Jesse Chung-Sean, Li, Hiu Ming, Wang, Yin, Mao, Ying, Ng, Ho-Keung, Zhou, Liang Fu

“…Recurrence and progression to higher grade lesions are characteristic behaviors of gliomas. Though IDH1 mutation frequently occurs and is considered as an…”
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MiR-22 is Frequently Downregulated in Medulloblastomas and Inhibits Cell Proliferation via the Novel Target PAPST1 by Xu, Qing-Fu, Pan, Ya-Wen, Li, Li-Chao, Zhou, Zheng, Huang, Qi-Lin, Pang, Jesse Chung-sean, Zhu, Xiao-Peng, Ren, Yong, Yang, Hui, Ohgaki, Hiroko, Lv, Sheng-Qing

“…Medulloblastoma is the most frequent malignant central nervous system tumor in children. MicroRNAs (miRs) are small, non‐coding RNAs that target protein‐coding…”
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MIR-137 Suppresses Growth and Invasion, is Downregulated in Oligodendroglial Tumors and Targets CSE1L by Li, Kay Ka-Wai, Yang, Ling, Pang, Jesse Chung-Sean, Chan, Aden Ka-Yin, Zhou, Liangfu, Mao, Ying, Wang, Yin, Lau, Kin-Mang, Poon, Wai Sang, Shi, Zhifeng, Ng, Ho-Keung

“…MicroRNA‐137 (miR‐137) expression has been reported to be decreased in astrocytic tumors in two expression profiling studies but its role in the pathogenesis…”
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Loss of CIC and FUBP1 expressions are potential markers of shorter time to recurrence in oligodendroglial tumors by Chan, Aden Ka-Yin, Pang, Jesse Chung-Sean, Chung, Nellie Yuk-Fei, Li, Kay Ka-Wai, Poon, Wai Sang, Chan, Danny Tat-Ming, Shi, Zhifeng, Chen, Liang, Zhou, Liangfu, Ng, Ho-Keung

“…Combined deletion of chromosomes 1p and 19q is a prognostic marker in oligodendroglial tumors. Recent studies in oligodendroglial tumors have unveiled…”
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Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization by TONG, Carol Y. K, HUI, Angela B. Y, YIN, Xiao-Lu, PANG, Jesse C. S, ZHU, Xian-Lun, POON, Wai-Sang, NG, Ho-Keung

“…Few studies have been conducted to investigate the genomic survey of oncogene amplification in medulloblastoma. Low frequency of N-myc, C-myc, and epidermal…”
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KIAA0495/PDAM Is Frequently Downregulated in Oligodendroglial Tumors and Its Knockdown by siRNA Induces Cisplatin Resistance in Glioma Cells by Pang, Jesse Chung-Sean, Li, Kay Ka-Wai, Lau, Kin-Mang, Ng, Yeung Lam, Wong, John, Chung, Nellie Yuk-Fei, Li, Hiu-Ming, Chui, Yiu-Loon, Lui, Vivian Wai Yan, Chen, Zhong-ping, Chan, Danny Tat-Ming, Poon, Wai Sang, Wang, Yin, Mao, Yin, Zhou, Liangfu, Ng, Ho-Keung

“…Co‐deletion of chromosomes 1p and 19q is a common event in oligodendroglial tumors (OTs), suggesting the presence of OT‐related genes. The aim of this study…”
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Glioblastoma stem cells resistant to temozolomide-induced autophagy by Fu, Jun, Liu, Zhi-gang, Liu, Xiao-mei, Chen, Fu-rong, Shi, Hong-liu, Pangjesse, Chung-sean, Ng, Ho-keung, Chen, Zhong-ping

“…Background Recent studies have demonstrated the existence of a small fraction of cells with features of primitive neural progenitor cells and tumor-initiating…”
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Overexpression of IL-7 enhances cisplatin resistance in glioma by Cui, Lei, Fu, Jun, Pang, Jesse Chung-Sean, Qiu, Zhi-Kun, Liu, Xiao-Mei, Chen, Fu-Rong, Shi, Hong-Liu, Ng, Ho-Keung, Chen, Zhong-Ping

“…Cisplatin is one of the most commonly used chemotherapeutic agents for glioma patients. In this study, array comparative genomic hybridization (aCGH) was used…”
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Concurrent Hypermethylation of Multiple Genes Is Associated with Grade of Oligodendroglial Tumors by DONG, SHU-MIN, PANG, JESSE CHUNG-SEAN, POON, WAI-SANG, HU, JIE, TO, KA-FAI, CHANG, ALEXANDER RUSSELL, NG, HO-KEUNG

“…Current evidence suggests that epigenetic changes play an important role in the evolution of human cancers. In this study, we evaluated whether…”
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Heterogeneous responses of aquaporin-4 in oedema formation in a replicated severe traumatic brain injury model in rats by Ke, Changshu, Poon, Wai Sang, Ng, Ho Keung, Pang, Jesse Chung-Sean, Chan, Yung

“…Aquaporin-4 (AQP4) is the most abundant water channel in the rat brain. In this study, the distribution pattern and mRNA expression levels of AQP4 were…”
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Whole Genome Amplification for Array Comparative Genomic Hybridization Using DNA Extracted from Formalin-Fixed, Paraffin-Embedded Histological Sections by Huang, Jian, Pang, Jesse, Watanabe, Takuya, Ng, Ho-Keung, Ohgaki, Hiroko

“…Array comparative genomic hybridization (CGH) is useful to assess genome-wide chromosomal imbalance, but the requirement for relatively large amounts of DNA…”
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