Search Results - "Paneda, Astrid"
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1
Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria
Published in Journal of hepatology (01-10-2016)“…Graphical abstract…”
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2
Insulin‐like growth factor I gene transfer to cirrhotic liver induces fibrolysis and reduces fibrogenesis leading to cirrhosis reversion in rats
Published in Hepatology (Baltimore, Md.) (01-03-2010)“…We investigated whether gene transfer of insulin‐like growth factor I (IGF‐I) to the hepatic tissue was able to improve liver histology and function in…”
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3
Mapping of QTLs for morpho-agronomic and seed quality traits in a RIL population of common bean (Phaseolus vulgaris L.)
Published in Theoretical and applied genetics (01-05-2010)“…The objective of this research was to determine the quantitative trait loci (QTLs) controlling phenological traits (days to flowering, days to end of…”
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4
Safety and liver transduction efficacy of rAAV5-cohPBGD in nonhuman primates: a potential therapy for acute intermittent porphyria
Published in Human gene therapy (01-12-2013)“…Acute intermittent porphyria (AIP) results from haplo-insufficient activity of porphobilinogen deaminase (PBGD) and is characterized clinically by…”
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5
Development of a Liver-specific Tet-On Inducible System for AAV Vectors and Its Application in the Treatment of Liver Cancer
Published in Molecular therapy (01-07-2011)“…Recombinant adeno-associated virus (rAAV) are effective gene delivery vehicles that can mediate long-lasting transgene expression. However, tight regulation…”
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6
Molecular mapping and intra-cluster recombination between anthracnose race-specific resistance genes in the common bean differential cultivars Mexico 222 and Widusa
Published in Theoretical and applied genetics (01-04-2008)“…Resistance to races 19, 31, 38, 65, 73, 102, and 449, of the pathogenic fungus Colletotrichum lindemuthianum (anthracnose) was evaluated in F₃ families derived…”
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genetic linkage map of Phaseolus vulgaris L. and localization of genes for specific resistance to six races of anthracnose (Colletotrichum lindemuthianum)
Published in Theoretical and applied genetics (01-02-2007)“…A genetic map of common bean was constructed using 197 markers including 152 RAPDs, 32 RFLPs, 12 SCARs, and 1 morphological marker. The map was established by…”
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8
Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12
Published in Journal of Virology (01-03-2009)“…Erratum ( vol. 85 , p. 13475 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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9
Adeno-associated virus liver transduction efficiency measured by in vivo [18F]FHBG positron emission tomography imaging in rodents and nonhuman primates
Published in Human gene therapy (01-08-2011)“…Recombinant adeno-associated virus 5 (rAAV5) represents a candidate vector with unique advantages for the treatment of hepatic disorders because of its narrow…”
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10
Molecular markers and allelic relationships of anthracnose resistance gene cluster B4 in common bean
Published in Euphytica (2005)“…Allelism tests and molecular marker analyses were combined to characterize the genes that, proceeding from the germplasm lines 'A493' and 'A321', confer…”
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11
Molecular therapy for obesity and diabetes based on a long‐term increase in hepatic fatty‐acid oxidation
Published in Hepatology (Baltimore, Md.) (01-03-2011)“…Obesity‐induced insulin resistance is associated with both ectopic lipid deposition and chronic, low‐grade adipose tissue inflammation. Despite their excess…”
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12
Intrahepatic injection of recombinant adeno-associated virus serotype 2 overcomes gender-related differences in liver transduction
Published in Human gene therapy (01-06-2006)“…The liver is an attractive organ for gene therapy because of its important role in many inherited and acquired diseases. Recombinant adeno-associated viruses…”
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13
Markers linked to the bc-3 gene conditioning resistance to bean common mosaic potyviruses in common bean
Published in Euphytica (01-08-2005)“…Necrotic strains of bean common mosaic potyviruses are becoming increasingly problematic in bean growing areas of Africa and Europe. Pyramiding epistatic…”
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14
Effect of adeno-associated virus serotype and genomic structure on liver transduction and biodistribution in mice of both genders
Published in Human gene therapy (01-08-2009)“…Recombinant adeno-associated viral (AAV) vectors have unique properties, which make them suitable vectors for gene transfer. Here we assess the liver…”
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15
Adeno-associated viral vector serotype 5 poorly transduces liver in rat models
Published in PloS one (27-12-2013)“…Preclinical studies in mice and non-human primates showed that AAV serotype 5 provides efficient liver transduction and as such seems a promising vector for…”
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16
Mapping and use of seed protein loci for marker-assisted selection of growth habit and photoperiod response in Nuña bean (Phaseolus vulgaris L.)
Published in Euphytica (01-06-2011)“…The individual segregations of 14 seed protein loci named, SpA to SpM and Pha (phaseolin), were analyzed in a RIL population developed from the cross…”
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17
Molecular markers linked to the fin gene controlling determinate growth habit in common bean
Published in Euphytica (01-07-2008)“…Bulked segregant analysis (BSA) was used to identify molecular markers linked to determinate growth habit (fin gene) in a F₂ population derived from the cross…”
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18
664. Improving AAV Gene Therapy Safety Analysis: Multiplex LAM-PCR Provide New Insights Into AAV Vector Integration
Published in Molecular therapy (01-05-2015)Get full text
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19
Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12
Published in Journal of virology (01-12-2011)Get full text
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20
Adeno-Associated Viral Vector Serotype 5 Poorly Transduces Liver in Rat Models: e82597
Published in PloS one (01-12-2013)“…Preclinical studies in mice and non-human primates showed that AAV serotype 5 provides efficient liver transduction and as such seems a promising vector for…”
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