Search Results - "Pane, Adriana"
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Extracellular vesicles in atherothrombosis and cardiovascular disease: Friends and foes
Published in Atherosclerosis (01-08-2021)“…Extracellular vesicles (EV, exosomes and microvesicles -MV-) are 30–1000 nm particles surrounded by a phospholipid bilayer membrane that are released from…”
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What is the evidence regarding the safety of new obesity pharmacotherapies
Published in International Journal of Obesity (09-02-2024)“…The use of gut-hormone receptors agonists as new therapeutic options for obesity and some of its related comorbidities, such as type 2 diabetes, has resulted…”
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Effects of Bariatric Surgery on Blood and Vascular Large Extracellular Vesicles According to Type 2 Diabetes Status
Published in The journal of clinical endocrinology and metabolism (21-12-2023)“…Abstract Context Large extracellular vesicles (lEVs) enriched for endothelial and blood cell markers are increased in metabolic conditions such as obesity or…”
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Use of the Steno T1 Risk Engine Identifies Preclinical Atherosclerosis Better Than Use of ESC/EASD-2019 in Adult Subjects With Type 1 Diabetes at High Risk
Published in Diabetes care (01-10-2022)“…To evaluate the concordance between the 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD…”
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Machine learning allows robust classification of visceral fat in women with obesity using common laboratory metrics
Published in Scientific reports (27-07-2024)“…The excessive accumulation and malfunctioning of visceral adipose tissue (VAT) is a major determinant of increased risk of obesity-related comorbidities. Thus,…”
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Impact of Preeclampsia and Parity on Sex-based Discrepancies in Subclinical Carotid Atherosclerosis in Type 1 Diabetes
Published in The journal of clinical endocrinology and metabolism (13-08-2024)“…Abstract Context The excess risk of fatal and nonfatal cardiovascular events is roughly twice as high in women than in men with type 1 diabetes. Objective To…”
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Endogenous cortisol excess confers a unique lipid signature and metabolic network
Published in Journal of molecular medicine (Berlin, Germany) (01-08-2021)“…Chronic cortisol excess induces several alterations on protein, lipid and carbohydrate metabolism resembling those found in the metabolic syndrome. However,…”
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Weight-loss thresholds after bariatric surgery and cardiovascular outcomes: more is better
Published in International Journal of Obesity (01-02-2022)“…Background/objectives Whether the extent of weight loss (WL) modulates bariatric surgery (BS) cardiovascular benefits has scarcely been assessed. Several WL…”
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Impact of Simultaneous Pancreas-kidney Transplantation on Cardiovascular Risk in Patients With Diabetes
Published in Transplantation (01-01-2022)“…Cardiovascular disease is the major cause of death in patients with type 1 diabetes. Of the available risk predictors for this population, the Steno Type 1…”
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Hypothalamic Inflammation Improves Through Bariatric Surgery, and Hypothalamic Volume Predicts Short-Term Weight Loss Response in Adults With or Without Type 2 Diabetes
Published in Diabetes care (01-07-2024)“…Preclinical research implicates hypothalamic inflammation (HI) in obesity and type 2 diabetes pathophysiology. However, their pathophysiological relevance and…”
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Carotid ultrasonography as a strategy to optimize cardiovascular risk management in type 1 diabetes: a cohort study
Published in Acta diabetologica (01-12-2022)“…Background and aims Although cardiovascular disease (CVD) remains the leading cause of mortality in type 1 diabetes (T1D), the use of cardioprotective drugs is…”
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Diabetic Neuropathy Is Independently Associated With Worse Graft Outcomes and Incident Cardiovascular Disease After Pancreas Transplantation: A Retrospective Cohort Study in Type 1 Diabetes
Published in Transplantation (01-02-2023)“…Information about the impact of diabetic neuropathy (DN) on outcomes after pancreas transplantation (PT) is scarce. We assessed the independent relationship…”
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Ten-year outcomes after Roux-en-Y gastric bypass and sleeve gastrectomy: an observational nonrandomized cohort study
Published in Surgery for obesity and related diseases (01-03-2019)“…•Ten-year weight loss was similar in patients with morbid obesity that underwent Roux-en-Y gastric bypass or Sleeve gastrectomy.•RYGB was similar to SG in…”
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Adherence to an energy‐restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes
Published in Diabetes/metabolism research and reviews (01-03-2024)“…Aims People with type 1 diabetes (T1D) have an increased risk of cardiovascular disease (CVD). The Mediterranean diet is associated with reduced CVD; however,…”
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Insulin resistance is associated with preclinical carotid atherosclerosis in patients with type 1 diabetes
Published in Diabetes/metabolism research and reviews (01-10-2020)“…Aim Although insulin resistance (IR) is a growing trait among type 1 diabetes (T1D) population, its relationship with atherosclerosis has been scarcely…”
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Dose-Dependent association of cumulative tobacco consumption with the presence of carotid atherosclerosis in individuals with type 1 diabetes
Published in Diabetes research and clinical practice (01-08-2024)“…Evaluate the association between cumulative tobacco consumption (CTC; packs-year) and atherosclerosis in type 1 diabetes (T1D), and study whether the inclusion…”
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Molecular mapping of platelet hyperreactivity in diabetes: the stress proteins complex HSPA8/Hsp90/CSK2α and platelet aggregation in diabetic and normal platelets
Published in Translational research : the journal of laboratory and clinical medicine (01-09-2021)“…The molecular understanding of the pathophysiological changes elicited by diabetes in platelets may help in further elucidating the involvement of this…”
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Severe hypoglycemia and hypoglycemia awareness are associated with preclinical atherosclerosis in patients with type 1 diabetes without an estimated high cardiovascular risk
Published in Diabetes/metabolism research and reviews (01-03-2024)“…Aims To explore the relationship between severe hypoglycemia (SH) and hypoglycemia awareness with preclinical atherosclerosis in type 1 diabetes (T1D)…”
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Preeclampsia Is Associated With Increased Preclinical Carotid Atherosclerosis in Women With Type 1 Diabetes
Published in The journal of clinical endocrinology and metabolism (01-01-2020)“…Although preeclampsia (PE) is a well-established cardiovascular risk factor (CVRF) in the general population, its role in type 1 diabetes (T1D) has been…”
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Neutrophil-to-lymphocyte ratio is independently associated with carotid atherosclerosis burden in individuals with type 1 diabetes
Published in Nutrition, metabolism, and cardiovascular diseases (01-02-2024)“…Recent studies have identified a relationship between innate versus. Adaptative immunity and cardiovascular disease (CVD) in the general population, but…”
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