Search Results - "Pandya, Pranav A."
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Simultaneous enantioseparation and simulation studies of atenolol, metoprolol and propranolol on Chiralpak® IG column using supercritical fluid chromatography
Published in Journal of pharmaceutical analysis (01-12-2021)“…Enantioseparation of three β-blockers, i.e., atenolol, metoprolol and propranolol, was studied on amylose tris(3-chloro-5-methylphenylcarbamate) immobilized…”
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Analytical separation of four stereoisomers of luliconazole using supercritical fluid chromatography: Thermodynamic aspects and simulation study with chiral stationary phase
Published in Journal of Chromatography A (16-08-2020)“…•First report on selective separation of four stereoisomers of luliconazole using chiral SFC.•Separation efficiency was mainly dependent on the nature and…”
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Separation of achiral anti-diabetic drugs using sub/supercritical fluid chromatography with a polysaccharide stationary phase: Thermodynamic considerations and molecular docking study
Published in Journal of pharmaceutical and biomedical analysis (10-09-2020)“…[Display omitted] •Selective separation of four achiral anti-diabetic drugs on chiral stationary phase (CSP) by SFC.•Separation of drugs was mainly dependent…”
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Application of supercritical fluid chromatography for separation and quantitation of 15 co‐formulated binary anti‐hypertensive medications using a single elution protocol
Published in Biomedical chromatography (01-04-2021)“…A facile supercritical fluid chromatography method is proposed to analyse 15 co‐formulated binary anti‐hypertensive drug combinations using a customized…”
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Facile separation of four co-formulated ternary antihypertensive drug combinations with a customized elution protocol using supercritical fluid chromatography
Published in Microchemical journal (01-12-2020)“…•A customized elution protocol was used for separation of four co-formulated ternary combinations.•Thermodynamic study revealed enthalpy driven process for the…”
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Design, synthesis and biological evaluation of novel 5-(4-chlorophenyl)-4-phenyl-4H-1,2,4-triazole-3-thiols as an anticancer agent
Published in Journal of molecular structure (05-05-2021)“…•Structure-based designing approach was used to identify novel 1,2,4-triazole-3-thiols as p53-MDM2 inhibitor.•Compounds were characterized by spectroscopic…”
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Novel N-thioamide analogues of pyrazolylpyrimidine based piperazine: Design, synthesis, characterization, in-silico molecular docking study and biological evaluation
Published in Journal of molecular structure (05-01-2019)“…Utilizing molecular hybridization approach, a progression of novel pyrazolylpyrimidine based N-thioamide derivatives of piperazine were identified in an effort…”
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Design, Synthesis and Biological Evaluation of Novel 5‐Phenyl‐5‐(thiophen‐2‐yl)‐4H‐1,2,4‐triazole‐3‐thiols as an Anticancer Agent
Published in ChemistrySelect (Weinheim) (08-04-2021)“…Tumor suppressor protein p53 is one of the most appealing targets for targeted anticancer therapy, due to its significant role in cancer prevention and…”
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Design, Synthesis and Biological Evaluation of Novel 5‐Phenyl‐5‐(thiophen‐2‐yl)‐4 H ‐1,2,4‐triazole‐3‐thiols as an Anticancer Agent
Published in ChemistrySelect (Weinheim) (08-04-2021)“…Abstract Tumor suppressor protein p53 is one of the most appealing targets for targeted anticancer therapy, due to its significant role in cancer prevention…”
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