Search Results - "Pandya, Nirali"

Piperine analogs arrest c-myc gene leading to downregulation of transcription for targeting cancer by Pandya, Nirali, Kumar, Amit

“…G-quadruplex (G4) structures are considered a promising therapeutic target in cancer. Since Ayurveda, Piperine has been known for its medicinal properties…”
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Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands by Majee, Prativa, Kumar Mishra, Subodh, Pandya, Nirali, Shankar, Uma, Pasadi, Sanjeev, Muniyappa, K., Nayak, Debasis, Kumar, Amit

“…The G-quadruplex (GQ) motifs are considered as potential drug-target sites for several human pathogenic viruses such as Zika, Hepatitis, Ebola, and Human…”
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Strigolactone analog GR24 triggers changes in PIN2 polarity, vesicle trafficking and actin filament architecture by Pandya‐Kumar, Nirali, Shema, Rony, Kumar, Manoj, Mayzlish‐Gati, Einav, Levy, Danny, Zemach, Hanita, Belausov, Eduard, Wininger, Smadar, Abu‐Abied, Mohamad, Kapulnik, Yoram, Koltai, Hinanit

“…Strigolactones (SLs) are plant hormones that regulate shoot and root development in a MAX2‐dependent manner. The mechanism underlying SLs' effects on roots is…”
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Immune landscape and redox imbalance during neurological disorders in COVID-19 by Thakur, Abhimanyu, Sharma, Vartika, Averbek, Sera, Liang, Lifan, Pandya, Nirali, Kumar, Gaurav, Cili, Alma, Zhang, Kui

“…The outbreak of Coronavirus Disease 2019 (COVID-19) has prompted the scientific community to explore potential treatments or vaccines against severe acute…”
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Influence of chirality of V(V) Schiff base complexes on DNA, BSA binding and cleavage activity by Khan, Noor-ul H., Pandya, Nirali, Maity, Nabin Ch, Kumar, Manoj, Patel, Rajesh M., Kureshy, Rukhsana I., Abdi, Sayed H.R., Mishra, Sandhya, Das, Satyabrata, Bajaj, Hari C.

“…New chiral V(V) Schiff base complexes ( S)-[VO(OMe) L] and ( R)-[VO(OMe) L] were synthesized and characterized by microanalysis, infrared (IR), UV–Visible,…”
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Strigolactone signaling in root development and phosphate starvation by Kumar, Manoj, Pandya-Kumar, Nirali, Kapulnik, Yoram, Koltai, Hinanit

“…Strigolactones (SLs), have recently been recognized as phytohormone involve in orchestrating shoot and root architecture. In, roots SLs positively regulate…”
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Comparative study of interspecific genetic divergence and phylogenic analysis of genus Jatropha by RAPD and AFLP by Sudheer Pamidiamarri, D. V. N, Pandya, Nirali, Reddy, Muppala P, Radhakrishnan, T

“…Genus Jatropha with 172 species having significant economic importance belongs to the family Euphorbiaceae. There are no reports on molecular characterization…”
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Immunoinformatics analysis for design of multi-epitope subunit vaccine by using heat shock proteins against Schistosoma mansoni by Pandya, Nirali, Kumar, Amit

“…The development of T cell and B cell that able provide long-term immune response against the schistosomiasisis to the people belongs to the epidemic area. Heat…”
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A multi-epitope vaccine candidate developed from unique immunogenic epitopes against Cryptosporidium hominis by utilizing an immunoinformatics-driven approach by Pandya, Nirali, Kumar, Amit

“…An immunoinformatics-based strategy is being investigated to identify prospective multi-subunit vaccine candidates against Cryptosporidium hominis (C…”
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An immunoinformatics analysis: design of a multi-epitope vaccine against Cryptosporidium hominis by employing heat shock protein triggers the innate and adaptive immune responses by Pandya, Nirali, Kumar, Amit

“…Cryptosporidium hominis, an anthropologically transferred species in the Cryptosporidium genus, represents many clinical studies in several countries. Its…”
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Regulatory role of Non-canonical DNA Polymorphisms in human genome and their relevance in Cancer by Pandya, Nirali, Bhagwat, Sonali R., Kumar, Amit

“…DNA has the ability to form polymorphic structures like canonical duplex DNA and non-canonical triplex DNA, Cruciform, Z-DNA, G-quadruplex (G4), i-motifs, and…”
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Discovery of a potent Guanidine derivative that selectively binds and stabilizes the human BCL-2 G-quadruplex DNA and downregulates the transcription by Pandya, Nirali, Rani, Reshma, Kumar, Vinit, Kumar, Amit

“…[Display omitted] •The Guanidine derivatives (GD-1 and GD-2) preferentially interact withBCL-2promoter G-quadruplexes (GQ) over other cancer-causing…”
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G-quadruplex-mediated specific recognition, stabilization and transcriptional repression of bcl-2 by small molecule by Pandya, Nirali, Singh, Mamta, Rani, Reshma, Kumar, Vinit, Kumar, Amit

“…The presence of the G-quadruplex (G4) structure in the promoter region of the human bcl-2 oncogenes makes it a promising target for developing anti-cancer…”
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Identification of selective plant-derived natural carotenoid and flavonoids as the potential inhibitors of DHHC-mediated protein S- palmitoylation: an in silico study by Chaturvedi, Suchi, Pandya, Nirali, Sadhukhan, Sushabhan, Sonawane, Avinash

“…Protein palmitoylation mediated by DHHCs is recognized as a distinct and reversible form of lipid modification connected with several health perturbations,…”
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Curcumin analogs exhibit anti-cancer activity by selectively targeting G-quadruplex forming c-myc promoter sequence by Pandya, Nirali, Khan, Eshan, Jain, Neha, Satham, Lakshminarayana, Singh, Rahul, Makde, Ravindra D., Mishra, Amit, Kumar, Amit

“…Curcumin exhibits a broad spectrum of beneficial health properties that include anti-tumor and anti-cancer activities. The down-regulation of c-myc…”
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Interaction analysis of anti-cancer drug Methotrexate with bcl-2 promoter stabilization and its transcription regulation by Pandya, Nirali, Jain, Neha, Kumar, Amit

“…G-quadruplex (G4) motifs are higher-order secondary structures putatively present in the promoter region of several oncogenes and telomeric ends of…”
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Multifaceted nucleic acid probing with a rationally upgraded molecular rotor by Kha, Tuan-Khoa, Shi, Qi, Pandya, Nirali, Zhu, Ru-Yi

“…Probing the sequence alterations, structures, interactions, and other important aspects of nucleic acids serves as the cornerstone of understanding nucleic…”
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Identification of substrates of MBL Associated Serine Protease-1 (MASP-1) from human plasma using N-terminomics strategy by Bhagwat, Sonali R., Choudhary, Komal, Pandya, Nirali, Sharma, Sadhana, Srivastava, Sanjeeva, Kumar, Amit, Hajela, Krishnan

“…MBL Associated Serine Protease-1 (MASP-1) is an abundant enzyme of the lectin complement pathway. MASP-1 cleaves numerous substrates like MASP-2, MASP-3, C2,…”
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Chiral discrimination asserted by enantiomers of Ni (II), Cu (II) and Zn (II) Schiff base complexes in DNA binding, antioxidant and antibacterial activities by Khan, Noor-ul Hasan, Pandya, Nirali, Prathap, K. Jeya, Kureshy, Rukhsana Ilays, Abdi, Sayed Hasan Razi, Mishra, Sandhya, Bajaj, Hari Chandra

“… Chiral Schiff base Ni (II), Cu (II) and Zn (II) complexes have been synthesized and characterized by various physico-chemical methods. All the complexes were…”
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Influence of chirality using Mn(III) salen complexes on DNA binding and antioxidant activity by Khan, Noor-Ul H, Pandya, Nirali, Kumar, Manoj, Bera, Prasanta Kumar, Kureshy, Rukhsana I, Abdi, Sayed H R, Bajaj, Hari C

“…Chiral Mn(iii) salen complexes S-1, R-1, S-2, R-2, S-3 and R-3 derived from the respective chiral salen ligands, viz.,…”
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