Search Results - "Pandya, Maya J."

Human Heat Shock Protein 70 Enhances Tumor Antigen Presentation through Complex Formation and Intracellular Antigen Delivery without Innate Immune Signaling by Bendz, Henriette, Ruhland, Sibylle C., Pandya, Maya J., Hainzl, Otmar, Riegelsberger, Stefan, Braüchle, Christoph, Mayer, Matthias P., Buchner, Johannes, Issels, Rolf D., Noessner, Elfriede

“…Heat shock proteins (HSPs) have shown promise for the optimization of protein-based vaccines because they can transfer exogenous antigens to dendritic cells…”
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Why the Energy Landscape of Barnase Is Hierarchical by Pandya, Maya J, Schiffers, Stefanie, Hounslow, Andrea M, Baxter, Nicola J, Williamson, Mike P

“…We have used NMR and computational methods to characterize the dynamics of the ribonuclease barnase over a wide range of timescales in free and inhibitor-bound…”
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Sequence and Structural Duality:  Designing Peptides to Adopt Two Stable Conformations by Pandya, Maya J, Cerasoli, Eleonora, Joseph, Abbey, Stoneman, Rhys G, Waite, Eleanor, Woolfson, Derek N

“…To improve our understanding of conformational transitions in proteins, we are attempting the de novo design of peptides that switch structural state. Here, we…”
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Interaction of human GTP cyclohydrolase I with its splice variants by Pandya, Maya J, Golderer, Georg, Werner, Ernst R, Werner-Felmayer, Gabriele

“…Tetrahydrobiopterin is an essential cofactor for aromatic amino acid hydroxylases, ether lipid oxidase and nitric oxide synthases. Its biosynthesis in mammals…”
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Backbone 1H, 13C and 15N resonance assignment of the ubiquitin specific protease 7 catalytic domain (residues 208–554) in complex with a small molecule ligand by Pandya, Maya J., Augustyniak, Wojciech, Cliff, Matthew J., Lindner, Ilka, Stinn, Anne, Kahmann, Jan, Temmerman, Koen, Dannatt, Hugh R. W., Waltho, Jonathan P., Watson, Martin J.

“…The backbone 1 H, 13 C and 15 N resonance assignment of Ubiquitin Specific Protease 7 catalytic domain (residues 208–554) was performed in its complex with a…”
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Site-Specific Identification of an Aβ Fibril-Heparin Interaction Site by Using Solid-State NMR Spectroscopy by Madine, Jillian, Pandya, Maya J., Hicks, Matthew R., Rodger, Alison, Yates, Edwin A., Radford, Sheena E., Middleton, David A.

“…At the surface of Aβ1‐40 amyloid fibrils that have a threefold molecular symmetry (green in the left picture) a site of interaction of the glycosaminoglycan…”
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Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets by Clinton, Tracy R., Weinstock, Matthew T., Jacobsen, Michael T., Szabo‐Fresnais, Nicolas, Pandya, Maya J., Whitby, Frank G., Herbert, Andrew S., Prugar, Laura I., McKinnon, Rena, Hill, Christopher P., Welch, Brett D., Dye, John M., Eckert, Debra M., Kay, Michael S.

“…Ebolaviruses are highly lethal filoviruses that cause hemorrhagic fever in humans and nonhuman primates. With no approved treatments or preventatives, the…”
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Sticky-End Assembly of a Designed Peptide Fiber Provides Insight into Protein Fibrillogenesis by Pandya, Maya J, Spooner, Gillian M, Sunde, Margaret, Thorpe, Julian R, Rodger, Alison, Woolfson, Derek N

“…Coiled-coil motifs provide simple systems for studying molecular self-assembly. We designed two 28-residue peptides to assemble into an extended coiled-coil…”
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Pressure-Dependent Structure Changes in Barnase on Ligand Binding Reveal Intermediate Rate Fluctuations by Wilton, David J., Kitahara, Ryo, Akasaka, Kazuyuki, Pandya, Maya J., Williamson, Mike P.

“…In this work we measured 1H NMR chemical shifts for the ribonuclease barnase at pressures from 3 MPa to 200 MPa, both free and bound to d(CGAC). Shift changes…”
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Dimerization of protein G B1 domain at low pH: A conformational switch caused by loss of a single hydrogen bond by Tomlinson, Jennifer H., Craven, C. Jeremy, Williamson, Mike P., Pandya, Maya J.

“…A number of signals in the NMR spectrum of the B1 domain of staphylococcal protein G (GB1) show a chemical shift dependence on the concentration of the protein…”
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Use of quantitative (1)H NMR chemical shift changes for ligand docking into barnase by Cioffi, Marina, Hunter, Christopher A, Packer, Martin J, Pandya, Maya J, Williamson, Mike P

“…(1)H NMR complexation-induced changes in chemical shift (CIS) of HN protons have been used to characterize the complexes of barnase with the…”
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Interaction of human heat shock protein 70 with tumor-associated peptides by Pandya, Maya J, Bendz, Henriette, Manzenrieder, Florian, Noessner, Elfriede, Kessler, Horst, Buchner, Johannes, Issels, Rolf D

“…Molecular chaperones of the heat shock protein 70 (Hsp70) family play a crucial role in the presentation of exogenous antigenic peptides by antigen-presenting…”
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Use of quantitative 1H NMR chemical shift changes for ligand docking into barnase by Cioffi, Marina, Hunter, Christopher A., Packer, Martin J., Pandya, Maya J., Williamson, Mike P.

“…1 H NMR complexation-induced changes in chemical shift (CIS) of HN protons have been used to characterize the complexes of barnase with the…”
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Biophysical Analysis of Natural Variants of the Multimerization Region of Epstein-Barr Virus Lytic-Switch Protein BZLF1 by Hicks, M R, Balesaria, S, Medina-Palazon, C, Pandya, M J, Woolfson, D N, Sinclair, A J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-κB Signalling by Long, Jed, Garner, Thomas P., Pandya, Maya J., Craven, C. Jeremy, Chen, Ping, Shaw, Barry, Williamson, Michael P., Layfield, Robert, Searle, Mark S.

“…The ubiquitin (Ub)-binding p62 scaffold protein (encoded by the SQSTM1 gene) regulates a diverse range of signalling pathways leading to activation of the…”
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Direct Kinetic Evidence for Folding via a Highly Compact, Misfolded State by Pandya, Maya J., Williams, Phil B., Dempsey, Christopher E., Shewry, Peter R., Clarke, Anthony R.

“…The 2 S seed storage protein, sunflower albumin 8 (SFA-8), contains an unusually high proportion of hydrophobic residues including 16 methionines (some of…”
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Backbone 1 H, 13 C and 15 N resonance assignment of the ubiquitin specific protease 7 catalytic domain (residues 208-554) in complex with a small molecule ligand by Pandya, Maya J, Augustyniak, Wojciech, Cliff, Matthew J, Lindner, Ilka, Stinn, Anne, Kahmann, Jan, Temmerman, Koen, Dannatt, Hugh R W, Waltho, Jonathan P, Watson, Martin J

“…The backbone H, C and N resonance assignment of Ubiquitin Specific Protease 7 catalytic domain (residues 208-554) was performed in its complex with a small…”
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Abstract A47: Investigating Zbtb protein recognition of epigenetically modified DNA by Terooatea, Tommy W., Pandya, Maya J., Chugg, Alan C., Buck-Koehntop, Bethany A.

“…Methylation of CpG dinucleotides is essential for genomic stability, control of gene expression and the regulation of chromatin structure in normal eukaryotic…”
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Site-Specific Identification of an A[beta] Fibril-Heparin Interaction Site by Using Solid-State NMR Spectroscopy by Madine, Jillian, Pandya, Maya J, Hicks, Matthew R, Rodger, Alison, Yates, Edwin A, Radford, Sheena E, Middleton, David A

“…At the surface of A[beta](1-40) amyloid fibrils that have a threefold molecular symmetry (green in the left picture) a site of interaction of the…”
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Engineering Increased Stability into Self-Assembled Protein Fibers by Smith, A. M., Banwell, E. F., Edwards, W. R., Pandya, M. J., Woolfson, D. N.

“…Two stages in the rational redesign of a peptide‐based, self‐assembling fiber (SAF) are described. The SAF system comprises two peptides designed to form an…”
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