Search Results - "Pandit, Lekha"

Fair and equitable treatment for multiple sclerosis in resource-poor regions: The need for off-label therapies and regional treatment guidelines by Pandit, Lekha

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No evidence of disease activity (NEDA) in multiple sclerosis - Shifting the goal posts by Pandit, Lekha

“…A combined endpoint measure to define no evidence of disease activity (NEDA) is becoming increasingly appealing in the treatment of multiple sclerosis (MS)…”
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Prevalence and patterns of demyelinating central nervous system disorders in urban Mangalore, South India by Pandit, Lekha, Kundapur, Rashmi

“…There is a dearth of epidemiological data about multiple sclerosis (MS) and related demyelinating disorders in India. In this study, a registry method was used…”
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Neuromyelitis optica spectrum disorders: An update by Pandit, Lekha

“…Recent advances in the understanding of neuromyelitis optica spectrum of disorders (NMOSD) have expanded. Diagnostic criteria have changed over the years. The…”
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Comparison of live and fixed cell-based assay performance: implications for the diagnosis of MOGAD in a low-middle income country by Pandit, Lekha, D’Cunha, Anitha, Malli, Chaithra, Sudhir, Akshatha

“…Background Though considered optimal, live cell-based assay (LCBA) is often unavailable for the diagnosis of myelin oligodendrocyte glycoprotein…”
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Editorial: MOGAD, current knowledge and future trends by Siritho, Sasitorn, Pandit, Lekha, Matiello, Marcelo

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Helicobacter pylori infection may influence prevalence and disease course in myelin oligodendrocyte glycoprotein antibody associated disorder (MOGAD) similar to MS but not AQP4-IgG associated NMOSD by Malli, Chaithra, Pandit, Lekha, D'Cunha, Anita, Sudhir, Akshatha

“…( persists after colonizing the gut in childhood, and potentially regulates host immune system through this process. Earlier studies have shown that infection…”
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Determining Effectiveness of "Off-Label Therapies" for Multiple Sclerosis in a Real-World Setting by Pandit, Lekha, Mustafa, Sharik, Sudhir, Akshatha, Malapur, Puneeth, D'Cunha, Anitha

“…To determine the factors, if any, that are associated with the efficacy of "off-label therapies" (OLTs) for multiple sclerosis (MS). Consecutive patients (N =…”
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Epidemiology and clinical features of demyelinating disorders in India by Pandit, Lekha, Mustafa, Sharik

“…Epidemiological and clinical features of demyelinating disorders in the Indian context have been sparsely reported. This paper aims to provide a review of…”
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Environmental factors related to multiple sclerosis in Indian population by Malli, Chaithra, Pandit, Lekha, D'Cunha, Anita, Mustafa, Sharik

“…Multiple sclerosis (MS) is less prevalent among Indians when compared to white populations. Genetic susceptibility remaining the same it is possible that…”
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Evaluating the role of HLA DRB1 alleles and oligoclonal bands in influencing clinical course of multiple sclerosis - A study from the Mangalore demyelinating disease registry by DCunha, Anitha, Pandit, Lekha, Malli, Chaithra, Sudhir, Akshatha

“…Background: The possible interaction between genetic and immunological factors in influencing clinical course of multiple sclerosis (MS) has not been studied…”
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MOG-IgG-associated disease has a stereotypical clinical course, asymptomatic visual impairment and good treatment response by Pandit, Lekha, Mustafa, Sharik, Nakashima, Ichiro, Takahashi, Toshyuki, Kaneko, Kimhiko

“…Objectives We investigated the clinical characteristics and treatment response in myelin oligodendrocyte glycoprotein antibody (MOG-IgG)-associated disease and…”
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Coexistence of autoantibodies and other autoimmune diseases with multiple sclerosis and related disorders - Experience from the Mangalore Demyelinating Disease Registry (MANDDIR) by Malli, Chaithra, Pandit, Lekha, D'Çunha, Mary, Sudhir, Akshatha

“…Background: Co-occurrence of other autoimmune disorders (AID) and autoantibodies in patients with autoimmune demyelinating CNS disorders have not been studied…”
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Insights into the Changing Perspectives of Multiple Sclerosis in India by Pandit, Lekha

“…Multiple Sclerosis (MS) is being diagnosed in increasing numbers in metropolitan cities of India for which the availability of specialist neurologists and…”
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Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes by Juryńczyk, Maciej, Weinshenker, Brian, Akman-Demir, Gulsen, Asgari, Nasrin, Barnes, David, Boggild, Mike, Chaudhuri, Abhijit, D’hooghe, Marie, Evangelou, Nikos, Geraldes, Ruth, Illes, Zsolt, Jacob, Anu, Kim, Ho Jin, Kleiter, Ingo, Levy, Michael, Marignier, Romain, McGuigan, Christopher, Murray, Katy, Nakashima, Ichiro, Pandit, Lekha, Paul, Friedemann, Pittock, Sean, Selmaj, Krzysztof, de Sèze, Jérôme, Siva, Aksel, Tanasescu, Radu, Vukusic, Sandra, Wingerchuk, Dean, Wren, Damian, Leite, Isabel, Palace, Jacqueline

“…Distinguishing aquaporin-4 IgG(AQP4-IgG)-negative neuromyelitis optica spectrum disorders (NMOSD) from opticospinal predominant multiple sclerosis (MS) is a…”
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Spontaneous remission lasting more than a decade in untreated AQP4 antibody-positive NMOSD by Pandit, Lekha, Mustafa, Sharik

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Association of vitamin D and multiple sclerosis in India by Pandit, Lekha, Ramagopalan, Sreeram V, Malli, Chaithra, D’Cunha, Anitha, Kunder, Ramya, Shetty, Rajesh

“…Background: Vitamin D deficiency is widely prevalent in India. The association between vitamin D status and multiple sclerosis (MS) has not been previously…”
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Anti Myelin Oligodendrocyte Glycoprotein associated Immunoglobulin G (AntiMOG-IgG)-associated Neuromyelitis Optica Spectrum Disorder with Persistent Disease Activity and Residual Cognitive Impairment by Pandit, Lekha, Nakashima, Ichiro, Mustafa, Sharik, Takahashi, Toshiyuki, Kaneko, Kimhiko

“…Antibodies targeting myelin oligodendrocyte glycoprotein (MOG) have been recently reported in association with idiopathic inflammatory central nervous system…”
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Consensus statement on immune modulation in multiple sclerosis and related disorders during the covid-19 pandemic: Expert group on behalf of the indian academy of neurology by Rohit, Bhatia, Padma Srivastava, M, Khurana, Dheeraj, Pandit, Lekha, Mathew, Thomas, Gupta, Salil, Netravathi, M, Nair, Sruthi, Singh, Gagandeep, Singhal, Bhim

“…Knowledge related to SARS-CoV-2 or 2019 novel coronavirus (2019-nCoV) is still emerging and rapidly evolving. We know little about the effects of this novel…”
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Evaluation of the established non-MHC multiple sclerosis loci in an Indian population by Pandit, Lekha, Ban, Maria, Sawcer, Stephen, Singhal, Bhim, Nair, Shyam, Radhakrishnan, Kurupath, Shetty, Rajesh, Misri, Z, Hegde, Suresh, Bhat, Irruvathur Gopalakrishna

“…Background: Multiple sclerosis (MS) is a chronic demyelinating neurodegenerative disorder with a strong genetic component. Objective: The prevalence of MS in…”
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