Search Results - "Pandit, Kusum"

Global methylation patterns in idiopathic pulmonary fibrosis by Rabinovich, Einat I, Kapetanaki, Maria G, Steinfeld, Israel, Gibson, Kevin F, Pandit, Kusum V, Yu, Guoying, Yakhini, Zohar, Kaminski, Naftali

“…Idiopathic Pulmonary Fibrosis (IPF) is characterized by profound changes in the lung phenotype including excessive extracellular matrix deposition,…”
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Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data by Corcoran, David L, Pandit, Kusum V, Gordon, Ben, Bhattacharjee, Arindam, Kaminski, Naftali, Benos, Panayiotis V

“…MicroRNAs (miRNAs) are short, non-coding RNA regulators of protein coding genes. miRNAs play a very important role in diverse biological processes and various…”
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MicroRNA regulatory networks in idiopathic pulmonary fibrosis by Pandit, Kusum V, Milosevic, Jadranka

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal scarring lung disease of unknown etiology, characterized by changes in microRNA…”
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MicroRNAs in idiopathic pulmonary fibrosis by Pandit, Kusum V, Milosevic, Jadranka, Kaminski, Naftali

“…In this review, we describe the recent advances in the understanding of the role of microRNAs in idiopathic pulmonary fibrosis (IPF), a chronic progressive and…”
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Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis by PANDIT, Kusum V, CORCORAN, David, RICHARDS, Thomas, SELMAN, Moises, WATKINS, Simon C, PARDO, Annie, BEN-YEHUDAH, Ahmi, BOUROS, Demosthenes, EICKELBERG, Oliver, RAY, Prabir, BENOS, Panayiotis V, KAMINSKI, Naftali, YOUSEF, Hanadie, YARLAGADDA, Manohar, TZOUVELEKIS, Argyris, GIBSON, Kevin F, KONISHI, Kazuhisa, YOUSEM, Samuel A, SINGH, Mandal, HANDLEY, Daniel

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal fibrotic lung disease characterized by profound changes in epithelial cell…”
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C-X-C motif chemokine 13 (CXCL13) is a prognostic biomarker of idiopathic pulmonary fibrosis by Vuga, Louis J, Tedrow, John R, Pandit, Kusum V, Tan, Jiangning, Kass, Daniel J, Xue, Jianmin, Chandra, Divay, Leader, Joseph K, Gibson, Kevin F, Kaminski, Naftali, Sciurba, Frank C, Duncan, Steven R

“…C-X-C motif chemokine 13 (CXCL13) mediates B-cell trafficking and is increased, proportionately to disease activity, in many antibody-mediated syndromes…”
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High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells by Zhang, Yingze, Handley, Daniel, Kaplan, Tommy, Yu, Haiying, Bais, Abha S, Richards, Thomas, Pandit, Kusum V, Zeng, Qilu, Benos, Panayiotis V, Friedman, Nir, Eickelberg, Oliver, Kaminski, Naftali

“…Transforming growth factor beta 1 (TGFβ1) plays a major role in many lung diseases including lung cancer, pulmonary hypertension, and pulmonary fibrosis. TGFβ1…”
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Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis by Kusko, Rebecca L, Brothers, 2nd, John F, Tedrow, John, Pandit, Kusum, Huleihel, Luai, Perdomo, Catalina, Liu, Gang, Juan-Guardela, Brenda, Kass, Daniel, Zhang, Sherry, Lenburg, Marc, Martinez, Fernando, Quackenbush, John, Sciurba, Frank, Limper, Andrew, Geraci, Mark, Yang, Ivana, Schwartz, David A, Beane, Jennifer, Spira, Avrum, Kaminski, Naftali

“…Despite shared environmental exposures, idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease are usually studied in isolation, and the…”
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Reconstructing dynamic microRNA-regulated interaction networks by Schulz, Marcel H., Pandit, Kusum V., Cardenas, Christian L. Lino, Ambalavanan, Namasivayam, Kaminski, Naftali, Bar-Joseph, Ziv

“…The regulation of gene expression in cells, including by microRNAs (miRNAs), is a dynamic process. Current methods for identifying miRNA targets by combining…”
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Regulation of alveolar septation by microRNA-489 by Olave, Nelida, Lal, Charitharth V, Halloran, Brian, Pandit, Kusum, Cuna, Alain C, Faye-Petersen, Ona M, Kelly, David R, Nicola, Teodora, Benos, Panayiotis V, Kaminski, Naftali, Ambalavanan, Namasivayam

“…MicroRNAs (miRs) are small conserved RNA that regulate gene expression. Bioinformatic analysis of miRNA profiles during mouse lung development indicated a role…”
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Let-7d microRNA affects mesenchymal phenotypic properties of lung fibroblasts by Huleihel, Luai, Ben-Yehudah, Ahmi, Milosevic, Jadranka, Yu, Guoying, Pandit, Kusum, Sakamoto, Koji, Yousef, Hanadie, LeJeune, Megan, Coon, Tiffany A, Redinger, Carrie J, Chensny, Lara, Manor, Ester, Schatten, Gerald, Kaminski, Naftali

“…MicroRNAs are small noncoding RNAs that inhibit protein expression. We have previously shown that the inhibition of the microRNA let-7d in epithelial cells…”
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First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy by Sen, Malabika, Thomas, Sufi M, Kim, Seungwon, Yeh, Joanne I, Ferris, Robert L, Johnson, Jonas T, Duvvuri, Umamaheswar, Lee, Jessica, Sahu, Nivedita, Joyce, Sonali, Freilino, Maria L, Shi, Haibin, Li, Changyou, Ly, Danith, Rapireddy, Srinivas, Etter, Jonathan P, Li, Pui-Kai, Wang, Lin, Chiosea, Simion, Seethala, Raja R, Gooding, William E, Chen, Xiaomin, Kaminski, Naftali, Pandit, Kusum, Johnson, Daniel E, Grandis, Jennifer R

“…Despite evidence implicating transcription factors, including STAT3, in oncogenesis, these proteins have been regarded as "undruggable." We developed a decoy…”
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Novel modeling of combinatorial miRNA targeting identifies SNP with potential role in bone density by Coronnello, Claudia, Hartmaier, Ryan, Arora, Arshi, Huleihel, Luai, Pandit, Kusum V, Bais, Abha S, Butterworth, Michael, Kaminski, Naftali, Stormo, Gary D, Oesterreich, Steffi, Benos, Panayiotis V

“…MicroRNAs (miRNAs) are post-transcriptional regulators that bind to their target mRNAs through base complementarity. Predicting miRNA targets is a challenging…”
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Cartilage oligomeric matrix protein in idiopathic pulmonary fibrosis by Vuga, Louis J, Milosevic, Jadranka, Pandit, Kusum, Ben-Yehudah, Ahmi, Chu, Yanxia, Richards, Thomas, Sciurba, Joshua, Myerburg, Michael, Zhang, Yingze, Parwani, Anil V, Gibson, Kevin F, Kaminski, Naftali

“…Idiopathic pulmonary fibrosis (IPF) is a progressive and life threatening disease with median survival of 2.5-3 years. The IPF lung is characterized by…”
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Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study by Drake, Wonder P, Oswald-Richter, Kyra, Richmond, Bradley W, Isom, Joan, Burke, Victoria E, Algood, Holly, Braun, Nicole, Taylor, Thyneice, Pandit, Kusum V, Aboud, Caroline, Yu, Chang, Kaminski, Naftali, Boyd, Alan S, King, Lloyd E

“…Sarcoidosis is a chronic granulomatous disease for which there are limited therapeutic options. This is the first randomized, placebo-controlled study to…”
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Retinoic Acid―related Orphan Receptor-α Is Induced in the Setting of DNA Damage and Promotes Pulmonary Emphysema by YING SHI, JIAOFEI CAO, PANDIT, Kusum V, ROSAS, Ivan O, CHOI, Augustine M. K, MORSE, Danielle, JANE GAO, LIANG ZHENG, GOODWIN, Andrew, CHANG HYOEK AN, PATEL, Avignat, LEE, Janet S, DUNCAN, Steven R, KAMINSKI, Naftali

“…The discovery that retinoic acid-related orphan receptor (Rora)-α is highly expressed in lungs of patients with COPD led us to hypothesize that Rora may…”
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C-X-C Motif Chemokine 13 (CXCL13) Is a Prognostic Biomarker of Idiopathic Pulmonary Fibrosis by VUGA, Louis J, TEDROW, John R, SCIURBA, Frank C, DUNCAN, Steven R, PANDIT, Kusum V, JIANGNING TAN, KASS, Daniel J, JIANMIN XUE, CHANDRA, Divay, LEADER, Joseph K, GIBSON, Kevin F, KAMINSKI, Naftali

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Profibrotic role of miR-154 in pulmonary fibrosis by Milosevic, Jadranka, Pandit, Kusum, Magister, Marcus, Rabinovich, Einat, Ellwanger, Daniel C, Yu, Guoying, Vuga, Louis J, Weksler, Benny, Benos, Panayiotis V, Gibson, Kevin F, McMillan, Michael, Kahn, Michael, Kaminski, Naftali

“…In this study, we explored the regulation and the role of up-regulated microRNAs in idiopathic pulmonary fibrosis (IPF), a progressive interstitial lung…”
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Alterations in gene expression and DNA methylation during murine and human lung alveolar septation by Cuna, Alain, Halloran, Brian, Faye-Petersen, Ona, Kelly, David, Crossman, David K, Cui, Xiangqin, Pandit, Kusum, Kaminski, Naftali, Bhattacharya, Soumyaroop, Ahmad, Ausaf, Mariani, Thomas J, Ambalavanan, Namasivayam

“…DNA methylation, a major epigenetic mechanism, may regulate coordinated expression of multiple genes at specific time points during alveolar septation in lung…”
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microRNA (miRNA) expression profiling predicts clinical outcome of carboplatin/paclitaxel-based therapy (CP) in metastatic melanoma (MM) treated on the intergroup trial E2603 by Villaruz, Liza Cosca, Huang, Grace, Romkes, Marjorie, Kirkwood, John M., Buch, Shama C., Nukui, Tomoko, Flaherty, Keith, Lee, Sandra J., Lee, Adrian, Pandit, Kusum, Abecassis, Irina, Nathanson, Katherine L., Benos, Panayiotis V, Tawbi, Hussein Abdul-Hassan

“…Abstract only…”
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