Search Results - "Pandey, V A"
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Ten Novel Mutations in the NR5A1 Gene Cause Disordered Sex Development in 46,XY and Ovarian Insufficiency in 46,XX Individuals
Published in The journal of clinical endocrinology and metabolism (01-07-2012)“…Context: Steroidogenic factor-1 (SF-1/NR5A1) is a nuclear receptor that regulates adrenal and reproductive development and function. NR5A1 mutations have been…”
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Competence assessment of senior vascular trainees using a carotid endarterectomy bench model
Published in British journal of surgery (01-10-2007)“…Background: Competency‐based assessment is being introduced to surgical training. The value of bench‐top technical skills assessment using a synthetic carotid…”
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Self-assessment of technical skill in surgery: the need for expert feedback
Published in Annals of the Royal College of Surgeons of England (01-05-2008)“…Technical skill has been formally assessed in the Fellow of the European Board of Vascular Surgery Examinations (FEBVS) since 2002. The aim of this study was…”
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The examination assessment of technical competence in vascular surgery
Published in British journal of surgery (01-09-2006)“…Background: The European Board of Surgery Qualification in Vascular Surgery is a pan‐European examination for vascular surgeons who have attained a national…”
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Mechanism of malarial haem detoxification inhibition by chloroquine
Published in Biochemical journal (15-04-2001)“…The haem detoxification pathway of the malaria parasite Plasmodium falciparum is a potential biochemical target for drug development. Free haem, released after…”
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Superficial Venous Disease Treatment - Is There Still a Role for Open Surgery in 2011 ?
Published in Acta chirurgica belgica (2011)“…The treatment of superficial venous disease (commonly described as varicose veins by the general public) has remained relatively constant over the past 100…”
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In silico and in vitro analysis of genetic variants of the equine CYP3A94, CYP3A95 and CYP3A97 isoenzymes
Published in Toxicology in vitro (01-10-2019)“…Cytochrome P450 enzymes (CYPs) of the equine CYP3A subfamily are predominantly involved in drug metabolism. In this study, genetic variants of the equine…”
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Assay of β-hematin formation by malaria parasite
Published in Journal of pharmaceutical and biomedical analysis (01-06-1999)“…Novel leads are urgently required for designing antimalarials due to the reduced efficacy of presently available drugs. The malaria parasite has a unique…”
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Validity of an Exam Assessment in Surgical Skill: EBSQ-VASC Pilot Study
Published in European journal of vascular and endovascular surgery (01-04-2004)“…Presented at the XVII Annual Meeting of the European Society for Vascular Surgery (ESVS), Dublin (September 2003) and awarded the prize of the best clinical…”
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10
Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome
Published in Nature genetics (01-03-2004)“…Deficient activities of multiple steroidogenic enzymes have been reported without and with Antley-Bixler syndrome (ABS), but mutations of corresponding…”
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Diversity and Function of Mutations in P450 Oxidoreductase in Patients with Antley-Bixler Syndrome and Disordered Steroidogenesis
Published in American journal of human genetics (01-05-2005)“…P450 oxidoreductase (POR) is the obligatory flavoprotein intermediate that transfers electrons from reduced nicotinamide adenine dinucleotide phosphate (NADPH)…”
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Biochemical analysis of mutations in P450 oxidoreductase
Published in Biochemical Society transactions (01-12-2006)“…All microsomal P450s require POR (cytochrome P450 reductase) for catalytic activity. Most of the clinically used drugs are metabolized by a small number of…”
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13
AAA benchmarking by Dr Foster: a cause for concern?
Published in Annals of the Royal College of Surgeons of England (01-05-2007)“…The publication of interpretable performance data for hospitals is an important service. In November 2002, the medical benchmarking company Dr Foster published…”
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14
A Colorimetric Assay for Heme in Biological Samples Using 96-Well Plates
Published in Analytical biochemistry (01-03-1999)Get full text
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15
Validation of a novel duplex ultrasound objective structured assessment of technical skills (DUOSATS) for arterial stenosis detection
Published in Heart, lung and vessels (01-01-2014)Get full text
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Venous surgical training in the era of endoluminal surgery
Published in Phlebology (01-09-2011)Get more information
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Protein Phosphatase 2A and Phosphoprotein SET Regulate Androgen Production by P450c17
Published in The Journal of biological chemistry (31-01-2003)“…Cytochrome P450c17 catalyzes 17α-hydroxylation needed for cortisol synthesis and 17,20 lyase activity needed to produce sex steroids. Serine phosphorylation…”
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Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite
Published in The Journal of biological chemistry (02-07-1999)“…Endoperoxide antimalarials based on the ancient Chinese drug Qinghaosu (artemisinin) are currently our major hope in the fight against drug-resistant malaria…”
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Do Workshops Improve the Technical Skill of Vascular Surgical Trainees?
Published in European journal of vascular and endovascular surgery (01-10-2005)“…Adjuncts to conventional surgical training are needed in order to address the reduction in working hours. This purpose of this study was to objectively assess…”
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Training for Carotid Intervention: Preparing the Next Generation
Published in European journal of vascular and endovascular surgery (01-05-2007)“…Background Carotid interventions are performed to reduce the cumulative risk of stroke. The success of the procedure is dependent upon maintaining low…”
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