Search Results - "Pandey, Radha Raman"

PIWI Slicing and RNA Elements in Precursors Instruct Directional Primary piRNA Biogenesis by Homolka, David, Pandey, Radha Raman, Goriaux, Coline, Brasset, Emilie, Vaury, Chantal, Sachidanandam, Ravi, Fauvarque, Marie-Odile, Pillai, Ramesh S.

“…PIWI proteins and PIWI-interacting RNAs (piRNAs) mediate repression of transposons in the animal gonads. Primary processing converts long single-stranded RNAs…”
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PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway by Yang, Zhaolin, Chen, Kuan-Ming, Pandey, Radha Raman, Homolka, David, Reuter, Michael, Janeiro, Bruno Kotska Rodino, Sachidanandam, Ravi, Fauvarque, Marie-Odile, McCarthy, Andrew A., Pillai, Ramesh S.

“…PIWI-interacting RNAs (piRNAs) guide PIWI proteins to suppress transposons in the cytoplasm and nucleus of animal germ cells, but how silencing in the two…”
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Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development by Mendel, Mateusz, Chen, Kuan-Ming, Homolka, David, Gos, Pascal, Pandey, Radha Raman, McCarthy, Andrew A., Pillai, Ramesh S.

“…Internal modification of RNAs with N6-methyladenosine (m6A) is a highly conserved means of gene expression control. While the METTL3/METTL14 heterodimer adds…”
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Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing by Mendel, Mateusz, Delaney, Kamila, Pandey, Radha Raman, Chen, Kuan-Ming, Wenda, Joanna M., Vågbø, Cathrine Broberg, Steiner, Florian A., Homolka, David, Pillai, Ramesh S.

“…The N6-methyladenosine (m6A) RNA modification is used widely to alter the fate of mRNAs. Here we demonstrate that the C. elegans writer METT-10 (the ortholog…”
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Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function by Wenda, Joanna M., Homolka, David, Yang, Zhaolin, Spinelli, Pietro, Sachidanandam, Ravi, Pandey, Radha Raman, Pillai, Ramesh S.

“…Small RNAs called PIWI-interacting RNAs (piRNAs) act as an immune system to suppress transposable elements in the animal gonads. A poorly understood adaptive…”
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Recruitment of Armitage and Yb to a transcript triggers its phased processing into primary piRNAs in Drosophila ovaries by Pandey, Radha Raman, Homolka, David, Chen, Kuan-Ming, Sachidanandam, Ravi, Fauvarque, Marie-Odile, Pillai, Ramesh S

“…Small RNAs called PIWI -interacting RNAs (piRNAs) are essential for transposon control and fertility in animals. Primary processing is the small RNA biogenesis…”
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Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice by Pandey, Radha Raman, Tokuzawa, Yoshimi, Yang, Zhaolin, Hayashi, Eri, Ichisaka, Tomoko, Kajita, Shimpei, Asano, Yuka, Kunieda, Tetsuo, Sachidanandam, Ravi, Chuma, Shinichiro, Yamanaka, Shinya, Pillai, Ramesh S.

“…Piwi-interacting RNAs (piRNAs) are gonad-specific small RNAs that provide defense against transposable genetic elements called transposons. Our knowledge of…”
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Primary piRNA biogenesis: caught up in a Maelstrom by Pandey, Radha Raman, Pillai, Ramesh S

“…Precursors for most Piwi‐interacting RNAs (piRNAs) are indistinguishable from other RNA polymerase II‐transcribed long non‐coding RNAs. So, it is currently…”
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The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition by Li, Lingyun, Krasnykov, Kyrylo, Homolka, David, Gos, Pascal, Mendel, Mateusz, Fish, Richard J., Pandey, Radha Raman, Pillai, Ramesh S.

“…The functional consequence of N6-methyladenosine (m6A) RNA modification is mediated by “reader” proteins of the YTH family. YTH domain-containing 2 (YTHDC2) is…”
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Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12 by Pandey, Radha Raman, Homolka, David, Olotu, Opeyemi, Sachidanandam, Ravi, Kotaja, Noora, Pillai, Ramesh S.

“…PIWI proteins and their associated small RNAs, called PIWI-interacting RNAs (piRNAs), restrict transposon activity in animal gonads to ensure fertility…”
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Kcnq1ot1/Lit1 Noncoding RNA Mediates Transcriptional Silencing by Targeting to the Perinucleolar Region by Mohammad, Faizaan, Pandey, Radha Raman, Nagano, Takashi, Chakalova, Lyubomira, Mondal, Tanmoy, Fraser, Peter, Kanduri, Chandrasekhar

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Regulation of m6A Transcripts by the 3ʹ→5ʹ RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline by Wojtas, Magdalena Natalia, Pandey, Radha Raman, Mendel, Mateusz, Homolka, David, Sachidanandam, Ravi, Pillai, Ramesh S.

“…N6-methyladenosine (m6A) is an essential internal RNA modification that is critical for gene expression control in most organisms. Proteins with a YTH domain…”
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The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing by Kanduri, Chandrasekhar, Thakur, Noopur, Pandey, Radha Raman

“…The underlying mechanisms linking antisense RNA, chromatin architecture and gene expression have not been fully elucidated. Here we show that long transcripts…”
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The Mammalian Cap-Specific m6Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues by Pandey, Radha Raman, Delfino, Elena, Homolka, David, Roithova, Adriana, Chen, Kuan-Ming, Li, Lingyun, Franco, Giulia, Vågbø, Cathrine Broberg, Taillebourg, Emmanuel, Fauvarque, Marie-Odile, Pillai, Ramesh S.

“…The 5′ end of eukaryotic mRNAs is protected by the m7G-cap structure. The transcription start site nucleotide is ribose methylated (Nm) in many eukaryotes,…”
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An Antisense RNA Regulates the Bidirectional Silencing Property of the Kcnq1 Imprinting Control Region by Thakur, Noopur, Tiwari, Vijay Kumar, Thomassin, Helene, Pandey, Radha Raman, Kanduri, Meena, Göndör, Anita, Grange, Thierry, Ohlsson, Rolf, Kanduri, Chandrasekhar

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The piRNAs forge an immune system for the genome by Muller, Sébastien, Raman Pandey, Radha, Pillai, Ramesh S

“…Genome integrity of germline is essential for the survival of any species. A dedicated defence mechanism based on small RNA called piRNA (PIWI-interacting RNA)…”
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NF-Y Regulates the Antisense Promoter, Bidirectional Silencing, and Differential Epigenetic Marks of the Kcnq1 Imprinting Control Region by Pandey, Radha Raman, Ceribelli, Michele, Singh, Prim B, Ericsson, Johan, Mantovani, Roberto, Kanduri, Chandrasekhar

“…Antisense transcription has been shown to be one of the hierarchies that control gene expression in eukaryotes. Recently, we have documented that the mouse…”
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Distribution, molecular characterization and phosphate solubilization activity of culturable endophytic fungi from crop plant roots in North East (NE) India by Surendirakumar, Kannaiah, Pandey, Radha Raman, Muthukumar, Thangavelu

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In Vitro Biological Activities of an Endophytic Fungus, Trichoderma sp. L2D2 Isolated from Anaphalis contorta by Nongthombam, Kistu Singh, Mutum, Shyamkesho Singh, Pandey, Radha Raman

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Counting the Cuts: MAZTER-Seq Quantifies m6A Levels Using a Methylation-Sensitive Ribonuclease by Pandey, Radha Raman, Pillai, Ramesh S.

“…Garcia-Campos et al. describe MAZTER-seq, which deploys a sequence-specific, methylation-sensitive bacterial single-stranded ribonuclease MazF to provide…”
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