Search Results - "Panchia, Ravindre"
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Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial
Published in PLoS medicine (08-11-2018)“…Cabotegravir (CAB) is a novel strand-transfer integrase inhibitor being developed for HIV treatment and prevention. CAB is formulated both as an…”
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Acceptability of Long-Acting Injectable Cabotegravir (CAB LA) in HIV-Uninfected Individuals: HPTN 077
Published in AIDS and behavior (01-09-2020)“…Long-acting injectable PrEP could offer an alternative to daily oral PrEP, improve adherence and protection, if found acceptable, safe and effective. HPTN 077…”
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3
Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial
Published in The Lancet (British edition) (09-11-2013)“…Summary Background Interim results from the children with HIV early antiretroviral (CHER) trial showed that early antiretroviral therapy (ART) was life-saving…”
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4
HIV testing and the HIV care continuum among sub-Saharan African men who have sex with men and transgender women screened for participation in HPTN 075
Published in PloS one (31-05-2019)“…Throughout the world, men who have sex with men (MSM) are at increased risk for HIV infection compared to heterosexual men. Little is known about awareness of…”
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5
Cost-Effectiveness of HIV Treatment as Prevention in Serodiscordant Couples
Published in The New England journal of medicine (31-10-2013)“…In this study, early initiation of antiretroviral therapy (ART) was shown to be more cost-effective than late initiation of ART in preventing disease…”
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Nurse versus doctor management of HIV-infected patients receiving antiretroviral therapy (CIPRA-SA): a randomised non-inferiority trial
Published in The Lancet (British edition) (03-07-2010)“…Summary Background Expanded access to combination antiretroviral therapy (ART) in resource-poor settings is dependent on task shifting from doctors to other…”
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HIV incidence in a multinational cohort of men and transgender women who have sex with men in sub-Saharan Africa: Findings from HPTN 075
Published in PloS one (25-02-2021)“…Few studies have assessed HIV incidence in men who have sex with men (MSM) and transgender women (TGW) in sub-Saharan Africa (SSA). We assessed HIV incidence…”
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HIV Incidence Among Pregnant and Nonpregnant Women in the FACTS-001 Trial: Implications for HIV Prevention, Especially PrEP Use
Published in Journal of acquired immune deficiency syndromes (1999) (01-12-2021)“…During pregnancy and postpartum period, the sexual behaviors of women and their partners change in ways that may either increase or reduce HIV risks. Pregnant…”
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Reactivity of routine HIV antibody tests in children who initiated antiretroviral therapy in early infancy as part of the Children with HIV Early Antiretroviral Therapy (CHER) trial: a retrospective analysis
Published in The Lancet infectious diseases (01-07-2015)“…Summary Background Early antiretroviral therapy (ART) and virological suppression can affect evolving antibody responses to HIV infection. We aimed to assess…”
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CD4 counts and viral loads of newly diagnosed HIV-infected individuals: implications for treatment as prevention
Published in PloS one (04-03-2014)“…To report the viral load and CD4 count in HIV-infected, antiretroviral naïve, first -time HIV-testers, not immediately eligible for treatment initiation by…”
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Uptake of antiretroviral treatment and viral suppression among men who have sex with men and transgender women in sub-Saharan Africa in an observational cohort study: HPTN 075
Published in International journal of infectious diseases (01-03-2021)“…•HIV-positive MSM and TGW in sub-Saharan Africa were followed up for 12 months.•ARV drug use more than doubled during follow-up.•Viral suppression rates nearly…”
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Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial
Published in Frontiers in immunology (20-09-2017)“…Early treatment of HIV-infected children and adults is important for optimal immune reconstitution. Infants' immune systems are more plastic and dynamic than…”
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HIV disease progression among women following seroconversion during a tenofovir-based HIV prevention trial
Published in PloS one (28-06-2017)“…Little is known regarding HIV disease outcomes among individuals who become infected with HIV while receiving antiretroviral medications for prevention. We…”
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Association of HIV diversity and virologic outcomes in early antiretroviral treatment: HPTN 052
Published in PloS one (08-05-2017)“…Higher HIV diversity has been associated with virologic outcomes in children on antiretroviral treatment (ART). We examined the association of HIV diversity…”
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HIV risk perception and sexual behavior among HIV-uninfected men and transgender women who have sex with men in sub-Saharan Africa: Findings from the HPTN 075 qualitative sub-study
Published in PLOS global public health (2022)“…There remains a limited understanding of how men who have sex with men (MSM) and transgender women (TGW) in sub-Saharan Africa (SSA) perceive their risk for…”
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Prevalence and Incidence of Sexually Transmitted Infection in Injectable Progestin Contraception Users in South Africa
Published in Frontiers in reproductive health (01-07-2021)“…Whether intramuscular depot medroxyprogesterone acetate (DMPA-IM) and norethisterone enanthate (NET-EN) have a differential impact on the incidence of sexually…”
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Antiretroviral Therapy for the Prevention of HIV-1 Transmission
Published in The New England journal of medicine (01-09-2016)“…In this report involving 1763 HIV-1 serodiscordant couples, the suppression of HIV-1 in the infected partner significantly decreased the transmission of…”
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18
Interest in Oral Pre-exposure Prophylaxis Among Men Who Have Sex with Men and Transfeminine Persons in HPTN 075, a Multi-center HIV Prevention Study in Sub-Saharan Africa (2015-2017)
Published in AIDS and behavior (27-09-2024)“…Use of oral pre-exposure prophylaxis (O-PrEP) for HIV prevention has not been fully utilized in sub-Saharan Africa, especially among key populations with high…”
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Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial
Published in The Lancet infectious diseases (01-04-2014)“…Summary Background Use of antiretroviral treatment for HIV-1 infection has decreased AIDS-related morbidity and mortality and prevents sexual transmission of…”
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Tenofovir 1% vaginal gel for prevention of HIV-1 infection in women in South Africa (FACTS-001): a phase 3, randomised, double-blind, placebo-controlled trial
Published in The Lancet infectious diseases (01-11-2018)“…Young women in southern Africa have substantial risk of HIV acquisition. Female-controlled biomedical interventions are needed to mitigate this risk. We aimed…”
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