Search Results - "Panchenko, Mikhail P."

Elastase-released Epidermal Growth Factor Recruits Epidermal Growth Factor Receptor and Extracellular Signal-regulated Kinases to Down-regulate Tropoelastin mRNA in Lung Fibroblasts by DiCamillo, Sandra J., Carreras, Isabel, Panchenko, Maria V., Stone, Phillip J., Nugent, Matthew A., Foster, Judith A., Panchenko, Mikhail P.

“…Elastase/anti-elastase imbalance is a hallmark of emphysema, a chronic obstructive pulmonary disease associated with the rupture and inefficient repair of…”
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Basic fibroblast growth factor decreases elastin gene transcription in aortic smooth muscle cells by Carreras, Isabel, Rich, Celeste B., Panchenko, Mikhail P., Foster, Judith Ann

“…The extracellular matrix (ECM) protein elastin plays an essential role in the cardiovascular system by imparting elasticity to blood vessel wall. In this…”
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EGF antagonizes TGF-beta-induced tropoelastin expression in lung fibroblasts via stabilization of Smad corepressor TGIF by Yang, Shenghong, Nugent, Matthew A, Panchenko, Mikhail P

“…We previously reported that neutrophil elastase (NE) downregulates transforming growth factor-beta (TGF-beta)-maintained tropoelastin mRNA levels in lung…”
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Up-regulation of a hydrogen peroxide–responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasia by Panchenko, Mikhail P, Silva, Nilsa, Stone, James R

“…Abstract Background Multiple lines of investigation have implicated hydrogen peroxide (H2 O2 ) as an important endogenous mediator of cell proliferation in the…”
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Protein Kinase CK1αLS Promotes Vascular Cell Proliferation and Intimal Hyperplasia by Panchenko, Mikhail P, Siddiquee, Zakir, Dombkowski, David M, Alekseyev, Yuriy O, Lenburg, Marc E, Walker, Jennifer D, MacGillivray, Thomas E, Preffer, Frederic I, Stone, James R

“…Protein kinase CK1α regulates several fundamental cellular processes including proliferation and differentiation. Up to four forms of this kinase are expressed…”
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Altered vascular activation due to deficiency of the NADPH oxidase component p22phox by Wang, He, Albadawi, Hassan, Siddiquee, Zakir, Stone, Jillian M, Panchenko, Mikhail P, Watkins, Michael T, Stone, James R

“…Abstract Background Reactive oxygen species generated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase play important roles in vascular…”
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Neutrophil elastase-initiated EGFR/MEK/ERK signaling counteracts stabilizing effect of autocrine TGF-beta on tropoelastin mRNA in lung fibroblasts by DiCamillo, Sandra J, Yang, Shenghong, Panchenko, Maria V, Toselli, Paul A, Naggar, Estee F, Rich, Celeste B, Stone, Phillip J, Nugent, Matthew A, Panchenko, Mikhail P

“…Neutrophil elastase (NE) plays an important role in emphysema, a pulmonary disease associated with excessive elastolysis and ineffective repair of interstitial…”
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Folding of Proteins with WD-Repeats:  Comparison of Six Members of the WD-Repeat Superfamily to the G Protein β Subunit by Garcia-Higuera, Irene, Fenoglio, Jessica, Li, Ying, Lewis, Carol, Panchenko, Mikhail P, Reiner, Orly, Smith, Temple F, Neer, Eva J

“…The family of WD-repeat proteins comprises over 30 different proteins that share a highly conserved repeating motif [Neer, E. J., Schmidt, C. J., Nambudripad,…”
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Heparin-binding EGF-like growth factor regulates elastin and FGF-2 expression in pulmonary fibroblasts by Liu, Jianghuai, Rich, Celeste B, Buczek-Thomas, Jo Ann, Nugent, Matthew A, Panchenko, Mikhail P, Foster, Judith Ann

“…Elastase degradation of elastin within alveolar walls is an important event in the development of pulmonary emphysema. In addition to elastolytic activities,…”
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Functional components of basic fibroblast growth factor signaling that inhibit lung elastin gene expression by Carreras, I, Rich, C B, Jaworski, J A, Dicamillo, S J, Panchenko, M P, Goldstein, R, Foster, J A

“…Previously, we have demonstrated that basic fibroblast growth factor (bFGF) decreases elastin gene transcription in confluent rat lung fibroblasts via the…”
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Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guanylyl cyclases and inhibits surfactant secretion by Panchenko, Mikhail P, Joyce-Brady, Martin, Starikova, Marina G, Oakes, Sean M, Adachi, Roberto, Brody, Jerome S, Dickey, Burton F

“…Alveolar epithelial type 2 (T2) cells isolated from the lungs of adult rats responded to exogenous atrial natriuretic peptide (ANP) by two signalling…”
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EGF SUPPRESSES TGF‐beta‐INDUCED ELASTOGENESIS IN LUNG FIBROBLASTS VIA STABILIZATION OF TGIF by Yang, Shenghong, Panchenko, Mikhail P.

“…Elastin is a principal component of elastic fibers, which confer to the mature lung resilience and structural integrity. Once deposited, elastin displays a…”
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Protein kinase CK1αLS mediates hydrogen peroxide stimulated vascular cell proliferation and intimal hyperplasia by Stone, James R., Panchenko, Mikhail P., Silva, Nilsa, Dombkowski, David M., Preffer, Frederic I., MacGillivray, Thomas E.

“…Abstract only…”
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Upregulation of a Hydrogen Peroxide Responsive pre-mRNA Binding Protein in Atherosclerosis and Intimal Hyperplasia by Panchenko, Mikhail P., Silva, Nilsa, Stone, James R.

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Na(+)-K(+)-ATPase-G protein coupling in myocardial sarcolemma: separation and reconstitution by Danilenko, M P, Turmukhambetova, V C, Yesirev, O V, Tkachuk, V A, Panchenko, M P

“…The cholinergic agonist carbachol produces a concentration-dependent (half-maximum inhibitory concentration = 0.9 microM) decrease in the Na(+)-K(+)-adenosine…”
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Sites Important for PLCβ2 Activation by the G Protein βγ Subunit Map to the Sides of the β Propeller Structure by Panchenko, Mikhail P., Saxena, Kumkum, Li, Ying, Charnecki, Sara, Sternweis, Pamela M., Smith, Temple F., Gilman, Alfred G., Kozasa, Tohru, Neer, Eva J.

“…The βγ subunits of the heterotrimeric GTP-binding proteins (G proteins) that couple heptahelical, plasma membrane-bound receptors to intracellular effector…”
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A member of the Y-box protein family interacts with an upstream element in the α1(I) collagen gene by Sun, Wei, Hou, Fuxiang, Panchenko, Mikhail P., Smith, Barbara D.

“…Transforming growth factor beta (TGF-β) stimulates protein complex formation on a TGF-β response element (TAE) found in the distal portion (−1624) of the…”
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Protein kinase CK1alphaLS promotes vascular cell proliferation and intimal hyperplasia by Panchenko, Mikhail P, Siddiquee, Zakir, Dombkowski, David M, Alekseyev, Yuriy O, Lenburg, Marc E, Walker, Jennifer D, Macgillivray, Thomas E, Preffer, Frederic I, Stone, James R

“…Protein kinase CK1alpha regulates several fundamental cellular processes including proliferation and differentiation. Up to four forms of this kinase are…”
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Type I receptor serine-threonine kinase preferentially expressed in pulmonary blood vessels by Panchenko, M P, Williams, M C, Brody, J S, Yu, Q

“…Type II and type I receptor serine-threonine kinases (RSTK) are important components of the transmembrane signaling machinery that allow cells to respond to…”
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Sites Important for PLCβ2 Activation by the G Protein βγ Subunit Map to the Sides of the β Propeller Structure by Mikhail P. Panchenko, Kumkum Saxena, Ying Li, Sara Charnecki, Pamela M. Sternweis, Temple F. Smith, Alfred G. Gilman, Tohru Kozasa, Eva J. Neer

“…The βγ subunits of the heterotrimeric GTP-binding proteins (G proteins) that couple heptahelical, plasma membrane-bound receptors to intracellular effector…”
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