Search Results - "Panchal, G."

Charge-exchange-driven interfacial antiferromagnetic ground state in La0.8Sr0.2MnO3 ultrathin films by Panchal, G., Stramaglia, F., Vaz, C. A. F.

“…The evolution of the magnetic ground state of ultrathin 0–10 unit cells (uc) thick La0.8Sr0.2MnO3 films interfaced to an antiferromagnetic…”
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Mitigating the Impact of Antibacterial Drug Resistance through Host-Directed Therapies: Current Progress, Outlook, and Challenges by Chiang, Chih-Yuan, Uzoma, Ijeoma, Moore, Richard T, Gilbert, Merle, Duplantier, Allen J, Panchal, Rekha G

“…Increasing incidences of multidrug resistance in pathogenic bacteria threaten our ability to treat and manage bacterial infection. The development and FDA…”
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Role of interdiffusion on the magnetism of ultrathin LaMnO3 films by Stramaglia, F., Panchal, G., Nolting, F., Vaz, C. A. F.

“…We present a detailed study of the magnetic, spectroscopic and structural properties of ultrathin LaMnO3 films deposited on SrTiO3(001) substrates by oxide…”
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A systematic screen of FDA-approved drugs for inhibitors of biological threat agents by Madrid, Peter B, Chopra, Sidharth, Manger, Ian D, Gilfillan, Lynne, Keepers, Tiffany R, Shurtleff, Amy C, Green, Carol E, Iyer, Lalitha V, Dilks, Holli Hutcheson, Davey, Robert A, Kolokoltsov, Andrey A, Carrion, Jr, Ricardo, Patterson, Jean L, Bavari, Sina, Panchal, Rekha G, Warren, Travis K, Wells, Jay B, Moos, Walter H, Burke, Raelyn L, Tanga, Mary J

“…The rapid development of effective medical countermeasures against potential biological threat agents is vital. Repurposing existing drugs that may have…”
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Rational design of small molecules as vaccine adjuvants by Wu, Tom Y-H, Singh, Manmohan, Miller, Andrew T, De Gregorio, Ennio, Doro, Francesco, D'Oro, Ugo, Skibinski, David A G, Mbow, M Lamine, Bufali, Simone, Herman, Ann E, Cortez, Alex, Li, Yongkai, Nayak, Bishnu P, Tritto, Elaine, Filippi, Christophe M, Otten, Gillis R, Brito, Luis A, Monaci, Elisabetta, Li, Chun, Aprea, Susanna, Valentini, Sara, Calabrό, Samuele, Laera, Donatello, Brunelli, Brunella, Caproni, Elena, Malyala, Padma, Panchal, Rekha G, Warren, Travis K, Bavari, Sina, O'Hagan, Derek T, Cooke, Michael P, Valiante, Nicholas M

“…Adjuvants increase vaccine potency largely by activating innate immunity and promoting inflammation. Limiting the side effects of this inflammation is a major…”
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Evaluation of Ebola Virus Inhibitors for Drug Repurposing by Madrid, Peter B, Panchal, Rekha G, Warren, Travis K, Shurtleff, Amy C, Endsley, Aaron N, Green, Carol E, Kolokoltsov, Andrey, Davey, Robert, Manger, Ian D, Gilfillan, Lynne, Bavari, Sina, Tanga, Mary J

“…A systematic screen of FDA-approved drugs was performed to identify compounds with in vitro antiviral activities against Ebola virus (EBOV). Compounds active…”
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Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity by Sen, Edanur, Kota, Krishna P, Panchal, Rekha G, Bavari, Sina, Kiris, Erkan

“…Botulinum neurotoxins (BoNTs) are known as the most potent bacterial toxins, which can cause potentially deadly disease botulism. BoNT Serotype A (BoNT/A) is…”
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Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections by Iversen, Patrick L, Warren, Travis K, Wells, Jay B, Garza, Nicole L, Mourich, Dan V, Welch, Lisa S, Panchal, Rekha G, Bavari, Sina

“…There are no currently approved treatments for filovirus infections. In this study we report the discovery process which led to the development of antisense…”
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Identification of a Small-Molecule Entry Inhibitor for Filoviruses by BASU, Arnab, BING LI, MOIR, Donald T, BAVARI, Sina, RAY, Ranjit, FARZAN, Michael R, LIJUN RONG, BOWLIN, Terry L, MILLS, Debra M, PANCHAL, Rekha G, CARDINALE, Steven C, BUTLER, Michelle M, PEET, Norton P, MAJGIER-BARANOWSKA, Helena, WILLIAMS, John D, PATEL, Ishan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide by Pandya, Unnati M, Egbuta, Chinaza, Abdullah Norman, Trefa M, Chiang, Chih-Yuan Edward, Wiersma, Valerie R, Panchal, Rekha G, Bremer, Edwin, Eggleton, Paul, Gold, Leslie I

“…The endoplasmic reticulum (ER) chaperone protein, calreticulin (CRT), is essential for proper glycoprotein folding and maintaining cellular calcium…”
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In vivo Oligomerization and Raft Localization of Ebola Virus Protein VP40 during Vesicular Budding by Panchal, Rekha G., Ruthel, Gordon, Kenny, Tara A., Kallstrom, George H., Lane, Douglas, Badie, Shirin S., Li, Limin, Bavari, Sina, Aman, M. Javad

“…The matrix protein VP40 plays a critical role in Ebola virus assembly and budding, a process that utilizes specialized membrane domains known as lipid rafts…”
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A Novel Toll-Like Receptor 2 Agonist Protects Mice in a Prophylactic Treatment Model Against Challenge With Bacillus anthracis by Chiang, Chih-Yuan, Lane, Douglas J, Zou, Yefen, Hoffman, Tim, Pan, Jianfeng, Hampton, Janice, Maginnis, Jillian, Nayak, Bishnu P, D'Oro, Ugo, Valiante, Nicholas, Miller, Andrew T, Cooke, Michael, Wu, Tom, Bavari, Sina, Panchal, Rekha G

“…Current therapies for anthrax include the use of antibiotics (i.e., doxycycline, and ciprofloxacin), an anthrax vaccine (BioThrax) and -specific, monoclonal…”
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Applications of In Vivo Imaging in the Evaluation of the Pathophysiology of Viral and Bacterial Infections and in Development of Countermeasures to BSL3/4 Pathogens by Bocan, Thomas M., Panchal, Rekha G., Bavari, Sina

“…While preclinical and clinical imaging have been applied to drug discovery/development and characterization of disease pathology, few examples exist where…”
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P2X7 Receptor Cell Surface Expression and Cytolytic Pore Formation Are Regulated by a Distal C-terminal Region by Smart, Megan L, Gu, Ben, Panchal, Rekha G, Wiley, James, Cromer, Brett, Williams, David A, Petrou, Steven

“…The importance of the cytosolic C-terminal region of the P2X7 receptor (P2X7R) is unquestioned, yet little is known about the functional domains of this region…”
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Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease by Mudhasani, Rajini R, Golden, Joseph W, Adam, Gregory C, Hartingh, Timothy J, Kota, Krishna P, Ordonez, David, Quackenbush, Corey R, Tran, Julie P, Cline, Curtis, Williams, Janice A, Zeng, Xiankun, Olsen, David B, Lieberman, Linda A, Boyce, Christopher, Ginnetti, Anthony, Meinig, J Matthew, Panchal, Rekha G, Mucker, Eric M

“…Although smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox)…”
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Proteomic Analysis of Non-human Primate Peripheral Blood Mononuclear Cells During Burkholderia mallei Infection Reveals a Role of Ezrin in Glanders Pathogenesis by Chiang, Chih-Yuan, Zhong, Yang, Ward, Michael D, Lane, Douglas J, Kenny, Tara, Rosario-Acevedo, Raysa, Eaton, Brett P, Treviño, Sylvia R, Chance, Taylor B, Hu, Meghan, Worsham, Patricia L, Waag, David M, Moore, Richard T, Cazares, Lisa H, Cote, Christopher K, Zhou, Yingyao, Panchal, Rekha G

“…, the causative agent of glanders, is a gram-negative intracellular bacterium. Depending on different routes of infection, the disease is manifested by…”
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Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens by Scarff, Jennifer M., Waidyarachchi, Samanthi L., Meyer, Christopher J., Lane, Douglas J., Chai, Weirui, Lemmon, Margaret M., Liu, Jiuyu, Butler, Michelle M., Bowlin, Terry L., Lee, Richard E., Panchal, Rekha G.

“…New antibiotics that are active against multi-drug-resistant strains and difficult-to-treat bacterial infections are needed. Synthetic modification of…”
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Comparative In Vitro Activity Profiles of Novel Bis-Indole Antibacterials against Gram-Positive and Gram-Negative Clinical Isolates by Butler, Michelle M, Williams, John D, Peet, Norton P, Moir, Donald T, Panchal, Rekha G, Bavari, Sina, Shinabarger, Dean L, Bowlin, Terry L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45 by Stanford, Stephanie M, Panchal, Rekha G, Walker, Logan M, Wu, Dennis J, Falk, Matthew D, Mitra, Sayantan, Damle, Sagar S, Ruble, David, Kaltcheva, Teodora, Zhang, Sheng, Zhang, Zhong-Yin, Bavari, Sina, Barrios, Amy M, Bottini, Nunzio

“…Many cellular signaling events are regulated by tyrosine phosphorylation and mediated by the opposing actions of protein tyrosine kinases and phosphatases…”
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Filovirus-Like Particles Produced in Insect Cells: Immunogenicity and Protection in Rodents by Warfield, Kelly L., Posten, Nichole A., Swenson, Dana L., Olinger, Gene G., Esposito, Dominic, Gillette, William K., Hopkins, Ralph F., Costantino, Julie, Panchal, Rekha G., Hartley, James L., Aman, M. Javad, Bavari, Sina

“…Background. Virus-like particles (VLPs) of Ebola virus (EBOV) and Marburg virus (MARV) produced in human 293T embryonic kidney cells have been shown to be…”
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