Search Results - "Panara, Maria R."

Effects of vitamin E supplementation on F2-Isoprostane and thromboxane biosynthesis in healthy cigarette smokers by PATRIGNANI, P, PANARA, M. R, CIPOLLONE, F, DAVI, G, GALLINA, P, BITTOLO BON, G, PATRONO, C, TACCONELLI, S, SETA, F, BUCCIARELLI, T, CIABATTONI, G, ALESSANDRINI, P, MEZZETTI, A, SANTINI, G, SCIULLI, M. G

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Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects by Panara, M R, Renda, G, Sciulli, M G, Santini, G, Di Giamberardino, M, Rotondo, M T, Tacconelli, S, Seta, F, Patrono, C, Patrignani, P

“…We evaluated whether therapeutic blood levels of meloxicam are associated with selective inhibition of monocyte cyclooxygenase (COX)-2 in vitro and ex vivo…”
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The human pharmacology of monocyte cyclooxygenase 2 inhibition by cortisol and synthetic glucocorticoids by Santini, Giovanna, Patrignani, Paola, Sciulli, Maria G., Seta, Francesca, Tacconelli, Stefania, Panara, Maria R., Ricciotti, Emanuela, Capone, Marta L., Patrono, Carlo

“…Background We studied the concentration dependence of the inhibitory effects of cortisol, 6‐methylprednisolone, and dexamethasone on cyclooxygenase‐2 (COX‐2)…”
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Effects of flurbiprofen and flurbinitroxybutylester on prostaglandin endoperoxide synthases by Santini, Giovanna, Sciulli, Maria G., Panara, Maria R., Padovano, Roberto, di Giamberardino, Maria, Rotondo, Maria T., Del Soldato, Piero, Patrignani, Paola

“…The aim of our study was to evaluate the selectivity of flurbiprofen and flurbinitroxybutylester for inhibition of the cyclooxygenase activity of prostaglandin…”
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Blocking the interleukin-1 receptor inhibits leukotriene B4 and prostaglandin E2 generation in human monocyte cultures by Conti, P, Panara, M R, Barbacane, R C, Placido, F C, Bongrazio, M, Reale, M, Dempsey, R A, Fiore, S

“…Interleukin-1 is a potent stimulator of arachidonic acid (AA) metabolism and this activity could be attributed to the activation of the prostaglandin-forming…”
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Human recombinant interleukin-1 receptor antagonist inhibits lymphocyte blastogenesis induced by concanavalin A Restorative effect of hrIL-1 by Conti, Pio, Reale, Marcella, Panara, Maria R., Barbacane, Renato C., Bongrazio, Mauro, Dempsey, Roy A.

“…Interleukin-1 (IL-1), mainly produced by monocyte-macrophages, is a polypeptide cytokine with pleiotropic biological effects. IL-1 plays an important role in…”
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Effects of Vitamin E Supplementation on F 2 -Isoprostane and Thromboxane Biosynthesis in Healthy Cigarette Smokers by Patrignani, Paola, Panara, Maria R., Tacconelli, Stefania, Seta, Francesca, Bucciarelli, Tonino, Ciabattoni, Giovanni, Alessandrini, Paola, Mezzetti, Andrea, Santini, Giovanna, Sciulli, Maria G., Cipollone, Francesco, Davı̀, Giovanni, Gallina, Pietro, Bon, Gabriele Bittolo, Patrono, Carlo

“…Background —Increased formation of 8-iso-prostaglandin (PG) F 2α and thromboxane (TX) A 2 , potent agonists of platelet and vascular thromboxane (TH)/PGH 2…”
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Inhibition of leukotriene B4(LTB4) by recombinant interleukin-1 receptor antagonist (IL-1RA) on human monocytes by Conti, Pio, Panara, Maria R., Barbacane, Renato C., Reale, Marcella, Bongrazio, Mauro, Dempsey, Roy A.

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The human pharmacology of monocyte cyclooxygenase 2 inhibition by cortisol and synthetic glucocorticoids by Santini, G

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Effects of the novel anti‐inflammatory compounds, N‐[2‐(cyclohexyloxy)‐4‐nitrophenyl] methanesulphonamide (NS‐398) and 5‐methanesulphonamido‐6‐(2, 4‐difluorothiophenyl)‐1‐indanone (L‐745, 337), on the cyclo‐oxygenase activity of human blood prostaglandin endoperoxide synthases by Panara, Maria R., Greco, Anita, Santini, Giovanna, Sciulli, Maria G., Rotondo, Maria T., Padovano, Roberto, Giamberardino, Maria, Cipollone, Francesco, Cuccurullo, Franco, Patrono, Carlo, Patrignani, Paola

“…1 We have evaluated the selectivity of ketoprofen and two novel nonsteroidal anti‐inflammatory drugs, N‐[2‐(cyclohexyloxy)‐4‐nitrophenyl]methanesulphonamide…”
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Induction of prostaglandin endoperoxide synthase‐2 in human monocytes associated with cyclo‐oxygenase‐dependent F 2 ‐isoprostane formation by Patrignani, Paola, Santini, Giovanna, Panara, Maria R., Sciulli, Maria G., Greco, Anita, Rotondo, Maria T., di Giamberardino, Maria, Maclouf, Jacques, Ciabattoni, Giovanni, Patrono, Carlo

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Induction of prostaglandin endoperoxide synthase‐2 in human monocytes associated with cyclo‐oxygenase‐dependent F2‐isoprostane formation by Patrignani, Paola, Santini, Giovanna, Panara, Maria R., Sciulli, Maria G., Greco, Anita, Rotondo, Maria T., Giamberardino, Maria, Maclouf, Jacques, Ciabattoni, Giovanni, Patrono, Carlo

“…1 The isoprostane 8‐epi‐prostaglandin (PG)F2α is produced by free radical‐catalyzed peroxidation of arachidonic acid. It may also be formed as a minor product…”
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Effects of nimesulide on constitutive and inducible prostanoid biosynthesis in human beings by Panara, Maria R., Padovano, Roberto, Sciulli, Maria G., Santini, Giovanna, Renda, Giulia, Rotondo, Maria T., Pace, Annamaria, Patrono, Carlo, Patrignani, Paola

“…Background The aim of this study was to test the hypothesis that nimesulide, a nonsteroidal antiinflammatory drug, or its principal metabolite…”
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Effects of nabumetone on prostanoid biosynthesis in humans by Cipollone, F, Ganci, A, Panara, M R, Greco, A, Cuccurullo, F, Patrono, C, Patrignani, P

“…The active metabolite of the anti-inflammatory drug nabumetone has been characterized as a selective inhibitor of the inducible prostaglandin H synthase…”
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Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers by Patrignani, P, Panara, M R, Tacconelli, S, Seta, F, Bucciarelli, T, Ciabattoni, G, Alessandrini, P, Mezzetti, A, Santini, G, Sciulli, M G, Cipollone, F, Davì, G, Gallina, P, Bon, G B, Patrono, C

“…Increased formation of 8-iso-prostaglandin (PG) F(2alpha) and thromboxane (TX) A(2), potent agonists of platelet and vascular thromboxane (TH)/PGH(2)…”
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Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothiophenyl)-1-indanone (L-745,337), on the cyclo-oxygenase activity of human blood prosta-glandin endoperoxide synthases by Panara, Maria R., Greco, Anita, Santini, Giovanna, Sciulli, Maria G., Rotondo, Maria T., Padovano, Roberto, di Giamberardino, Maria, Cipollone, Francesco, Cuccurullo, Franco, Patrono, Carlo, Patrignani, Paola

“…1 We have evaluated the selectivity of ketoprofen and two novel nonsteroidal anti-inflammatory drugs, N -[2-(cyclohexyloxy)-4-nitrophenyl]methanesulphonamide…”
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Effect of interleukin-1 receptor antagonist on vascular smooth muscle cell proliferation by Porreca, E, Di Febbo, C, Barbacane, R C, Panara, M R, Cuccurullo, F, Conti, P

“…The development of the atheromatous plaque is largely dependent on vascular smooth muscle cell proliferation and production of biologically active compounds…”
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Inhibition of granuloma formation induced by potassium permanganate in the mouse by a specific human recombinant receptor antagonist for interleukin-1 (hrIL-1ra) by Conti, P, Panara, M R, Fridas, S, Barbacane, R C, Grilli, A, Placido, F C, Reale, M, Fiore, S

“…Interleukin-1 (IL-1) is a polypeptide which mediates several systemic changes associated with infection, inflammation and injury, such as fever, neutrophilia,…”
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Role of lipoxins A4 and B4 in the generation of arachidonic acid metabolites by rat mast cells and their effect on [3H]serotonin release by Conti, P, Reale, M, Barbacane, R C, Panara, M R, Bongrazio, M, Theoharides, T C

“…Basophils located in tissues are called mast cells and are found in connective tissue. Many different compounds are secreted from basophil granules upon…”
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Inhibition of leukotriene B4(LTB4) by recombinant interleukin-1 receptor antagonist (IL-1RA) on human monocytes by Conti, Pio, Panara, Maria R., Barbacane, Renato C., Reale, Marcella, Bongrazio, Mauro, Dempsey, Roy A.

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