Search Results - "Pan, Zui"
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Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases
Published in Acta pharmacologica Sinica (01-07-2018)“…Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-inflammatory functions. The association between zinc deficiency and the…”
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Targeting calcium signaling in cancer therapy
Published in Acta pharmaceutica Sinica. B (01-01-2017)“…The intracellular calcium ions(Ca2+) act as second messenger to regulate gene transcription,cell proliferation, migration and death. Accumulating evidences…”
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3
A Fokker–Planck feedback control framework for optimal personalized therapies in colon cancer-induced angiogenesis
Published in Journal of mathematical biology (01-03-2022)“…In this paper, a new framework for obtaining personalized optimal treatment strategies in colon cancer-induced angiogenesis is presented. The dynamics of colon…”
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Near infrared fluorescent peptide nanoparticles for enhancing esophageal cancer therapeutic efficacy
Published in Nature communications (04-07-2018)“…Various types of nanoparticles have been proposed for targeted drug delivering, imaging, and tracking of therapeutic agents. However, highly biocompatible…”
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Zinc transporters and dysregulated channels in cancers
Published in Frontiers in bioscience (01-01-2017)“…As a nutritionally essential metal ion, zinc (Zn) not only constitutes a structural element for more than 3000 proteins but also plays important regulatory…”
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6
Quantum confined peptide assemblies with tunable visible to near-infrared spectral range
Published in Nature communications (13-08-2018)“…Quantum confined materials have been extensively studied for photoluminescent applications. Due to intrinsic limitations of low biocompatibility and…”
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Selective inhibitory effects of zinc on cell proliferation in esophageal squamous cell carcinoma through Orai1
Published in The FASEB journal (01-01-2018)“…Zinc, an essential micronutrient, has a cancer preventive role. Zinc deficiency has been shown to contribute to the progression of esophageal cancer. Orai1, a…”
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Store-Operated Calcium Channels as Drug Target in Gastroesophageal Cancers
Published in Frontiers in pharmacology (03-05-2021)“…Gastroesophageal cancers, including tumors occurring in esophagus and stomach, usually have poor prognosis and lack effective chemotherapeutic drugs for…”
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Editorial: Ion channels & homeostasis of ions in cancer cell fate
Published in Frontiers in oncology (22-12-2022)Get full text
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MG53 nucleates assembly of cell membrane repair machinery
Published in Nature cell biology (01-01-2009)“…A phosphatidylserine-binding protein, MG53, is shown to participate in membrane repair. MG53 recruits vesicles to the repair site in an oxidation dependent…”
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NAADP mobilizes calcium from acidic organelles through two-pore channels
Published in Nature (28-05-2009)“…Ca2+ mobilization from intracellular stores represents an important cell signalling process that is regulated, in mammalian cells, by…”
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In Esophageal Squamous Cells From Eosinophilic Esophagitis Patients, Th2 Cytokines Increase Eotaxin-3 Secretion Through Effects on Intracellular Calcium and a Non-Gastric Proton Pump
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2021)“…In upper airway cells, T helper 2 cytokines that signal through interleukin-4 (IL-4) receptor-α have been shown to stimulate eotaxin-3 secretion via a…”
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Non-alcoholic fatty liver disease combined with rheumatoid arthritis exacerbates liver fibrosis by stimulating co-localization of PTRF and TLR4 in rats
Published in Frontiers in pharmacology (06-06-2023)“…Rheumatoid arthritis (RA) has a high prevalence in patients with non-alcoholic fatty liver disease (NAFLD); however, the underlying mechanism is unclear. To…”
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14
Store-operated Ca2+ entry in muscle physiology and diseases
Published in BMB reports (01-02-2014)“…Ca(2+) release from intracellular stores and influx from extracellular reservoir regulate a wide range of physiological functions including muscle contraction…”
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Developing a Mathematical Model of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in Esophageal Cancer
Published in International journal of molecular sciences (03-02-2022)“…Targeting dysregulated Ca signaling in cancer cells is an emerging chemotherapy approach. We previously reported that store-operated Ca entry (SOCE) blockers,…”
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Open Sesame: treasure in store-operated calcium entry pathway for cancer therapy
Published in Science China. Life sciences (01-01-2015)“…Store-operated Ca^2+ entry(SOCE) controls intracellular Ca^2+ homeostasis and regulates a wide range of cellular events including proliferation,migration and…”
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Correcting Calcium Dysregulation in Chronic Heart Failure Using SERCA2a Gene Therapy
Published in International journal of molecular sciences (05-04-2018)“…Chronic heart failure (CHF) is a major contributor to cardiovascular disease and is the leading cause of hospitalization for those over the age of 65, which is…”
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Sarcolipin overexpression improves muscle energetics and reduces fatigue
Published in Journal of applied physiology (1985) (15-04-2015)“…Sarcolipin (SLN) is a regulator of sarcoendoplasmic reticulum calcium ATPase in skeletal muscle. Recent studies using SLN-null mice have identified SLN as a…”
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RNAseq of Osteoarthritic Synovial Tissues: Systematic Literary Review
Published in Frontiers in aging (25-05-2022)“…Osteoarthritis (OA) is one of the most common causes of disability in aged people, and it is defined as a degenerative arthropathy, characterized by the…”
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Using wearable biological sensors to provide personalized feedback to motivate behavioral changes: Study protocol for a randomized controlled physical activity intervention in cancer survivors (Project KNOWN)
Published in PloS one (13-09-2022)“…Regular physical activity reduces the progression of several cancers and offers physical and mental health benefits for cancer survivors. However, many cancer…”
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