Search Results - "Pan, Yingzhou Edward"
-
1
Functional analysis of CASK transcript variants expressed in human brain
Published in PloS one (16-06-2021)“…The calcium-/calmodulin dependent serine protein kinase (CASK) belongs to the membrane-associated guanylate kinases (MAGUK) family of proteins. It fulfils…”
Get full text
Journal Article -
2
Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish
Published in Communications biology (25-06-2021)“…The most common genetic cause of amyotrophic lateral sclerosis (ALS) and fronto-temporal dementia (FTD) is a hexanucleotide repeat expansion within the C9orf72…”
Get full text
Journal Article -
3
NMJ Analyser: a novel method to quantify neuromuscular junction morphology in zebrafish
Published in Bioinformatics (Oxford, England) (01-12-2023)“…Neuromuscular junction (NMJ) structural integrity is crucial for transducing motor neuron signals that initiate skeletal muscle contraction. Zebrafish has…”
Get full text
Journal Article -
4
Regulated resurfacing of a somatostatin receptor storage compartment fine-tunes pituitary secretion
Published in The Journal of cell biology (06-01-2020)“…The surfacing of the glucose transporter GLUT4 driven by insulin receptor activation provides the prototypic example of a homeostasis response dependent on…”
Get full text
Journal Article -
5
Delayed vacuolation in mammalian cells caused by hypotonicity and ion loss
Published in Scientific reports (26-11-2024)“…Prolonged exposure of mammalian cells to hypotonic environments stimulates the development of sometimes large and numerous vacuoles of unknown origin. Here, we…”
Get full text
Journal Article -
6
Missense mutations in CASK, coding for the calcium‐/calmodulin‐dependent serine protein kinase, interfere with neurexin binding and neurexin‐induced oligomerization
Published in Journal of neurochemistry (01-05-2021)“…Mutations in the X‐linked gene coding for the calcium‐/calmodulin‐dependent serine protein kinase (CASK) are associated with severe neurological disorders…”
Get full text
Journal Article -
7
Characterization of agonist-dependent somatostatin receptor subtype 2 trafficking in neuroendocrine cells
Published in Endocrine (01-09-2020)“…Background Somatostatin (SOM) receptor subtype 2 (SSTR2) is the major receptor subtype mediating SOM effects throughout the neuraxis. We previously…”
Get full text
Journal Article -
8
Characterization of Somatostatin Receptor Type 2A Intracellular Trafficking in Cells Co-expressing Somatostatin Receptor Type 2A and 5
Published 01-01-2015“…Somatostatin exerts a primarily inhibitory effect across multiple physiological systems, including endocrine and exocrine secretions, through a family of 5…”
Get full text
Dissertation