Search Results - "Pan, Yanyou"

Neuroprotective effects of apelin-13 on experimental ischemic stroke through suppression of inflammation by Xin, Qing, Cheng, Baohua, Pan, Yanyou, Liu, Haiqing, yang, Chunqing, Chen, Jing, Bai, Bo

“…•Apelin-13 reduces neurological deficits after ischemic stroke.•Apelin-13 decreases cerebral infarct volumes induced by ischemic stroke.•Apelin-13 inhibits the…”
Get full text

The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases by Wang, Chunmei, Wang, Qinqin, Ji, Bingyuan, Pan, Yanyou, Xu, Chao, Cheng, Baohua, Bai, Bo, Chen, Jing

“…Orexins, also known as hypocretins, are two neuropeptides secreted from orexin-containing neurons, mainly in the lateral hypothalamus (LH). Orexins orchestrate…”
Get full text

Heterodimerization of Mouse Orexin type 2 receptor variants and the effects on signal transduction by Wang, Chunmei, Pan, Yanyou, Zhang, Rumin, Bai, Bo, Chen, Jing, Randeva, Harpal S.

“…Orexin-A and Orexin-B play important roles in many physiological processes in which Orexins orchestrate diverse downstream effects via two G-protein coupled…”
Get full text

Ghrelin Through GHSR1a and OX1R Heterodimers Reveals a Gαs-cAMP-cAMP Response Element Binding Protein Signaling Pathway in Vitro by Xue, Qingjie, Bai, Bo, Ji, Bingyuan, Chen, Xiaoyu, Wang, Chunmei, Wang, Peixiang, Yang, Chunqing, Zhang, Rumin, Jiang, Yunlu, Pan, Yanyou, Cheng, Baohua, Chen, Jing

“…Growth hormone secretagogue receptor 1α (GHSR1a) and Orexin 1 receptor (OX1R) are involved in various important physiological processes, and have many similar…”
Get full text

Global gene expression profile of cerebral ischemia-reperfusion injury in rat MCAO model by Wang, Chunmei, Liu, Minghui, Pan, Yanyou, Bai, Bo, Chen, Jing

“…It is well-established that reperfusion following cerebral ischemic injury gives rise to secondary injury accompanied by structural and functional damage…”
Get full text

Orexin-A protects against oxygen-glucose deprivation/reoxygenation-induced cell damage by inhibiting endoplasmic reticulum stress-mediated apoptosis via the Gi and PI3K signaling pathways by Kong, Tingting, Qiu, Kaixin, Liu, Minghui, Cheng, Baohua, Pan, Yanyou, Yang, Chunqing, Chen, Jing, Wang, Chunmei

“…The neuropeptide orexin-A (OXA) has a neuroprotective effect, acting as an anti-apoptotic factor in response to multiple stimuli. Apoptosis induced by…”
Get full text

Association of lymphoid tissue‐resident commensal bacteria in mice with depressive‐like behaviors induced by chronic social defeat stress by Xie, Ruining, Jiang, Pei, Lin, Li, Yu, Bin, Wang, Chunmei, Pan, Yanyou, Rao, Jingjing, Wei, Wei, Qiao, Yi

“…Emerging evidence suggests that the microbiota‐gut‐brain axis affects a variety of complex behaviors, including social, emotional, and depressive‐like…”
Get full text

Neuroprotection of bradykinin/bradykinin B2 receptor system in cerebral ischemia by Ji, Bingyuan, Cheng, Baohua, Pan, Yanyou, Wang, Chunmei, Chen, Jing, Bai, Bo

“…Bradykinin B2 receptor (B2R) activated by its endogenous ligand bradykinin participates in various physiological processes including neurogenesis, neuronal…”
Get full text

Apelin‑13 attenuates ER stress‑associated apoptosis induced by MPP+ in SH‑SY5Y cells by Jiang, Yunlu, Liu, Haiqing, Ji, Bingyuan, Wang, Zhengwen, Wang, Chunmei, Yang, Chunqing, Pan, Yanyou, Chen, Jing, Cheng, Baohua, Bai, Bo

“…Apelin-13, a neuropeptide that acts as a ligand for a putative receptor related to the angiotensin II type receptor, elicits neuroprotective effects in…”
Get full text

Transmembrane peptide 4 and 5 of APJ are essential for its heterodimerization with OX1R by Wan, Lei, Xu, Fangfang, Liu, Chang, Ji, Bingyuan, Zhang, Rumin, Wang, Peixiang, Wu, Fei, Pan, Yanyou, Yang, Chunqing, Wang, Chunmei, Chen, Jing

“…Increasing evidence indicates some G protein-coupled receptors function as a heterodimer, which provide a novel target for therapeutics investigation. However,…”
Get full text

Orexin receptors exert a neuroprotective effect in Alzheimer’s disease (AD) via heterodimerization with GPR103 by Davies, Julie, Chen, Jing, Pink, Ryan, Carter, David, Saunders, Nigel, Sotiriadis, Georgios, Bai, Bo, Pan, Yanyou, Howlett, David, Payne, Annette, Randeva, Harpal, Karteris, Emmanouil

“…Orexins are neuropeptides that regulate the sleep-wake cycle and feeding behaviour. QRFP is a newly discovered neuropeptide which exerts similar orexigenic…”
Get full text

Identification of Conserved and Novel microRNAs in Cerebral Ischemia-Reperfusion Injury of Rat Using Deep Sequencing by Wang, Chunmei, Pan, Yanyou, Cheng, Baohua, Chen, Jing, Bai, Bo

“…MicroRNAs are a class of noncoding small RNAs that regulate gene expression by inhibiting target genes at post-transcriptional levels. MicroRNAs have been…”
Get full text

Edaravone protected PC12 cells against MPP(+)-cytoxicity via inhibiting oxidative stress and up-regulating heme oxygenase-1 expression by Cheng, Baohua, Guo, Yunliang, Li, Chuangang, Ji, Bingyuan, Pan, Yanyou, Chen, Jing, Bai, Bo

“…Abstract Oxidative stress is involved in the pathogenesis of Parkinson's disease (PD). Edaravone has been shown to have a neuroprotective effect. In the…”
Get full text

C-terminus of OX2R significantly affects downstream signaling pathways by Wang, Chunmei, Xu, Chao, Liu, Minghui, Pan, Yanyou, Bai, Bo, Chen, Jing

“…The human orexin 2 receptor (OX2R) is a G-protein‑coupled receptor (GPCR) that has been implicated in a number of diverse physiological functions. Recent…”
Get full text