Search Results - "Pan, Xiuyi"
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Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma
Published in Nature communications (06-09-2021)“…TFE3 -translocation renal cell carcinoma ( TFE3 -tRCC) is a rare and heterogeneous subtype of kidney cancer with no standard treatment for advanced disease. We…”
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Integrated Molecular Characterization of Fumarate Hydratase-deficient Renal Cell Carcinoma
Published in Clinical cancer research (15-03-2021)“…Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare but lethal subtype of RCC. Little is known about the genomic profile of…”
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A Rare Case of Synchronous Fumarate Hydratase-Deficient Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma With Fumarate Hydratase and von Hippel-Lindau Gene Mutations: A Clinicopathologic and Molecular Study
Published in International journal of surgical pathology (01-06-2024)“…Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare and aggressive tumor characterized by pathogenic alterations in the fumarate…”
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4
A novel intronic circular RNA circFGFR1int2 up-regulates FGFR1 by recruiting transcriptional activators P65/FUS and suppressing miR-4687-5p to promote prostate cancer progression
Published in Journal of translational medicine (22-11-2023)“…Abstract Fibroblast growth factor receptor 1 (FGFR1) is a core component of the FGFs/FGFR pathway that activates multiple signalling pathways, including…”
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circEZH2E2/E3 is a dual suppressor of miR363/miR708 to promote EZH2 expression and prostate cancer progression
Published in Cancer science (01-04-2023)“…The histone methyltransferase enhancer of zeste homolog 2 (EZH2) is overexpressed in a variety of malignancies including prostate cancer (PCa) and may play…”
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Atypical metanephric adenoma: Shares similar histopathological features and molecular changes of metanephric adenoma and epithelial-predominant Wilms’ tumor
Published in Frontiers in oncology (14-10-2022)“…Background Metanephric adenomas (MAs) are rare, benign renal tumors. Wilms’ tumors (WTs) are malignant embryonic tumors that originated from nephrogenic…”
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A primary intracranial neuroepithelial neoplasm with novel TCF3::BEND2 fusion: a case report
Published in Acta neuropathologica communications (11-11-2024)“…Astroblastoma, MN1-altered, is a rare circumscribed glial neoplasm that is composed of round, cuboidal, orcolumnar cells with astroblastic perivascular…”
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Epigenetic modification of PHLDA2 is associated with tumor microenvironment and unfavorable outcome of immune checkpoint inhibitor-based therapies in clear cell renal cell carcinoma
Published in European journal of medical research (20-07-2024)“…A substantial proportion of patients with metastatic clear cell renal cell carcinoma (ccRCC) cannot derive benefit from immune checkpoint inhibitor (ICI) plus…”
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Genomic and transcriptomic features between primary and paired metastatic fumarate hydratase-deficient renal cell carcinoma
Published in Genome medicine (02-05-2023)“…Fumarate hydratase-deficient renal cell carcinoma (FH-RCC) is a rare highly aggressive subtype of kidney cancer for which the distinct genomic, transcriptomic,…”
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Morphological and genetic characteristics of 21 papillary renal neoplasms with reverse polarity
Published in Asian journal of surgery (01-09-2024)Get full text
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AKR1B10 Is a New Sensitive and Specific Marker for Fumarate Hydratase-Deficient Renal Cell Carcinoma
Published in Modern pathology (01-11-2023)“…Fumarate hydratase (FH)–deficient renal cell carcinoma (RCC) is a rare and distinct subtype of renal cancer caused by FH gene mutations. FH negativity and…”
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The roles of mutated SPINK1 gene in prostate cancer cells
Published in Mutagenesis (08-12-2022)“…SPINK1-positive prostate cancer (PCa) has been identified as an aggressive PCa subtype. However, there is a lack of definite studies to elucidate the…”
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circEZH2 E2 /E3 is a dual suppressor of miR363/miR708 to promote EZH2 expression and prostate cancer progression
Published in Cancer science (01-04-2023)“…The histone methyltransferase enhancer of zeste homolog 2 (EZH2) is overexpressed in a variety of malignancies including prostate cancer (PCa) and may play…”
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14
Circulating tumour DNA reveals genetic traits of patients with intraductal carcinoma of the prostate
Published in BJU international (01-03-2022)“…Objectives To investigate the genetic alterations of patients with prostate cancer (PCa) with and without intraductal carcinoma of the prostate (IDC‐P)…”
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The expression profile and heterogeneity analysis of ERG in 633 consecutive prostate cancers from a single center
Published in The Prostate (01-06-2019)“…Background Overexpression of ERG protein resulting from TMPRSS2:ERG rearrangement is highly specific for prostate cancer (PCa). However, the biological…”
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Benign metastasizing fumarate hydratase (FH)-deficient uterine leiomyomas: clinicopathological and molecular study with first documentation of multi-organ metastases
Published in Virchows Archiv : an international journal of pathology (01-08-2024)“…Leiomyoma is the most prevalent benign tumor of the female reproductive system. Benign metastasizing leiomyoma (BML) is a rare phenomenon that presents at…”
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Genomic and Evolutionary Characterization of Concurrent Intraductal Carcinoma and Adenocarcinoma of the Prostate
Published in Cancer research (Chicago, Ill.) (02-01-2024)“…Intraductal carcinoma of the prostate (IDC-P) is a lethal prostate cancer subtype that generally coexists with invasive high-grade prostate acinar…”
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Different lasers in the treatment of benign prostatic hyperplasia: a network meta-analysis
Published in Scientific reports (24-03-2016)“…All available surgical treatments for benign prostatic hyperplasia (BPH) have their individual advantages or disadvantages. However, the lack of head-to-head…”
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Memory/Active T-Cell Activation Is Associated with Immunotherapeutic Response in Fumarate Hydratase-Deficient Renal Cell Carcinoma
Published in Clinical cancer research (03-06-2024)“…Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare and lethal subtype of kidney cancer. However, the optimal treatments and…”
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The expression profile and prognostic value of SPINK1 in initially diagnosed bone metastatic prostate cancer
Published in The Prostate (01-06-2016)“…BACKGROUND SPINK1 has been described to be mutually exclusively expressed in prostate cancer (PCa), but its expression profiles and the probable roles in bone…”
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