Search Results - "Pan, Xi‐Chun"
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Iron‐Catalyzed Radical Relay Enabling the Modular Synthesis of Fused Pyridines from Alkyne‐Tethered Oximes and Alkenes
Published in Angewandte Chemie International Edition (21-12-2020)“…We have rationally designed a new class of alkyne‐tethered oximes and applied them in an unprecedented iron‐catalyzed radical relay protocol for the rapid…”
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Dual Role of Triptolide in Interrupting the NLRP3 Inflammasome Pathway to Attenuate Cardiac Fibrosis
Published in International journal of molecular sciences (16-01-2019)“…In a previous paper, we reported that triptolide (TP), a commonly used immunomodulator, could attenuate cardiac hypertrophy. This present study aimed to…”
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The Chinese Herbal Formula Huoxiang Zhengqi Dropping Pills Prevents Acute Intestinal Injury Induced by Heatstroke by Increasing the Expression of Claudin-3 in Rats
Published in Evidence-based complementary and alternative medicine (31-07-2022)“…Intestinal injury has been regarded as an important causative factor for systemic inflammation during heatstroke, and maintaining intestinal integrity has been…”
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Cardiomyocytic FoxP3 is involved in Parkin-mediated mitophagy during cardiac remodeling and the regulatory role of triptolide
Published in Theranostics (01-01-2022)“…Forkhead/winged helix transcriptional factor P3 (FoxP3) is a well-studied transcription factor that maintains the activity of T cells, but whether…”
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Effect of Triptolide on Temporal Expression of Cell Cycle Regulators During Cardiac Hypertrophy
Published in Frontiers in pharmacology (04-09-2020)“…Adult mammalian cardiomyocytes may reenter the cell cycle and cause cardiac hypertrophy. Triptolide (TP) can regulate the expressions of various cell cycle…”
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Triptolide Upregulates Myocardial Forkhead Helix Transcription Factor p3 Expression and Attenuates Cardiac Hypertrophy
Published in Frontiers in pharmacology (30-11-2016)“…The forkhead/winged helix transcription factor (Fox) p3 can regulate the expression of various genes, and it has been reported that the transfer of…”
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Modular Assembly of 2‑Aminoaniline Derivatives by Merging Hydroxylamine-Passerini and Hetero-Cope Rearrangement
Published in Organic letters (23-02-2024)“…A metal-free three-component protocol that combines a hydroxylamine-Passerini reaction and hetero-Cope rearrangement was realized, which enables the modular…”
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Artesunate enhances the antibacterial effect of β-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC
Published in Journal of antimicrobial chemotherapy (01-04-2011)“…Objectives Occasionally, we found that artesunate enhanced the antibacterial effects of antibiotics in vitro. Therefore, the enhancement of various beta…”
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Berichtigung: Iron‐Catalyzed Radical Relay Enabling the Modular Synthesis of Fused Pyridines from Alkyne‐Tethered Oximes and Alkenes
Published in Angewandte Chemie (26-09-2022)Get full text
Journal Article -
11
Iron‐Catalyzed Radical Relay Enabling the Modular Synthesis of Fused Pyridines from Alkyne‐Tethered Oximes and Alkenes
Published in Angewandte Chemie (21-12-2020)“…We have rationally designed a new class of alkyne‐tethered oximes and applied them in an unprecedented iron‐catalyzed radical relay protocol for the rapid…”
Get full text
Journal Article -
12
Cyclin-Dependent Kinase Inhibitor p21WAF1/CIP1 Facilitates the Development of Cardiac Hypertrophy
Published in Cellular physiology and biochemistry (2017)“…Abstract Background/Aims: Adult cardiomyocytes can re-enter cell cycle as stimulated by prohypertrophic factors although they withdraw from cell cycle soon…”
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Self-limiting bidirectional positive feedback between P53 and P21 is involved in cardiac hypertrophy
Published in European journal of pharmacology (15-10-2022)“…Pathological cardiac hypertrophy is an independent risk factor of cardiovascular diseases. Although the function of p53 and p21 in pathological cardiac…”
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Cyclin-Dependent Kinase Inhibitor p21 WAF1/CIP1 Facilitates the Development of Cardiac Hypertrophy
Published in Cellular physiology and biochemistry (01-10-2017)“…Background/Aims: Adult cardiomyocytes can re-enter cell cycle as stimulated by prohypertrophic factors although they withdraw from cell cycle soon after birth…”
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Artesunate enhances the antibacterial effect of {beta}-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC
Published in Journal of antimicrobial chemotherapy (01-04-2011)“…Occasionally, we found that artesunate enhanced the antibacterial effects of antibiotics in vitro. Therefore, the enhancement of various β-lactam antibiotics…”
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CPT-11 Chemotherapy Rescued A Patient with Atypical Sclerosing Epithelioid Fibrosarcoma from Emergent Condition
Published in Chinese journal of cancer research (01-03-2012)“…Sclerosing epithelioid fibrosarcoma (SEF) is a rare and poorly defined variant of fibrosarcoma, but generally insensitive to chemotherapy and progresses with…”
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