Search Results - "Pan, Liqiang"
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1
Emerging new therapeutic antibody derivatives for cancer treatment
Published in Signal transduction and targeted therapy (07-02-2022)“…Monoclonal antibodies constitute a promising class of targeted anticancer agents that enhance natural immune system functions to suppress cancer cell activity…”
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2
Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling
Published in Cell (07-03-2019)“…Receptor clustering on the cell membrane is critical in the signaling of many immunoreceptors, and this mechanism has previously been attributed to the…”
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3
The effect of cationic albumin-conjugated PEGylated tanshinone IIA nanoparticles on neuronal signal pathways and neuroprotection in cerebral ischemia
Published in Biomaterials (01-09-2013)“…Abstract Targeted treatment of ischemic stroke remains problem due to the complex pathogenesis of this disease and the difficulty in drug delivery across the…”
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4
Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance
Published in Nature communications (30-07-2022)“…Acquired resistance to cetuximab in colorectal cancers is partially mediated by the acquisition of mutations located in the cetuximab epitope in the epidermal…”
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A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models
Published in Signal transduction and targeted therapy (03-09-2021)Get full text
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6
Editorial: Targeting TNF/TNFR signaling pathways
Published in Frontiers in pharmacology (04-01-2023)Get full text
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7
T Cell Receptor-Directed Bispecific T Cell Engager Targeting MHC-Linked NY-ESO-1 for Tumor Immunotherapy
Published in Biomedicines (01-04-2024)“…Antibody-based bispecific T cell engagers (TCEs) that redirect T cells to kill tumor cells have shown a promising therapeutic effect on hematologic…”
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8
The Diversity and Similarity of Transmembrane Trimerization of TNF Receptors
Published in Frontiers in cell and developmental biology (14-10-2020)“…Receptors in the tumor necrosis factor receptor superfamily (TNFRSF) regulate proliferation of immune cells or induce programmed cell death, and many of them…”
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DNA‐Mediated Assembly of Multispecific Antibodies for T Cell Engaging and Tumor Killing
Published in Advanced science (01-01-2020)“…Targeting T‐cells against cancer cells is a direct means of treating cancer, and has already shown great responses in clinical treatment of B‐cell…”
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10
A reliability-based track fusion algorithm
Published in PloS one (07-05-2015)“…The common track fusion algorithms in multi-sensor systems have some defects, such as serious imbalances between accuracy and computational cost, the same…”
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TCR-mimic antibody-drug conjugates targeting intracellular tumor-specific mutant antigen KRAS G12V mutation
Published in Asian journal of pharmceutical sciences (01-11-2020)“…Limited clinical application of antibody-drug conjugates (ADCs) targeting tumor associated antigens (TAAs) is usually caused by on-target off-tumor side…”
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12
Study on Measure Approach of Void Fraction in Narrow Channel Based on Fully Convolutional Neural Network
Published in Frontiers in energy research (29-01-2021)“…Void fraction is one of the key parameters for gas-liquid study and detection of nuclear power system state. Based on fully convolutional neural network (FCN)…”
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13
Transcytosis, Antitumor Activity and Toxicity of Staphylococcal Enterotoxin C2 as an Oral Administration Protein Drug
Published in Toxins (16-06-2016)“…Staphylococcal enterotoxin C2 (SEC2) is a classical superantigen (SAg), which can tremendously activate T lymphocytes at very low dosage, thus exerting its…”
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14
Cooperation or Competition: An Evolutionary Game Study between Commercial Banks and Big Data-Based E-Commerce Financial Institutions in China
Published in Discrete Dynamics in Nature and Society (01-01-2015)“…On the premise of participants’ bounded rationality and information asymmetry, this paper focuses on the cooperation or competition relationship between…”
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Identification of boiling flow pattern in narrow rectangular channel based on TFA-CNN combined method
Published in Flow measurement and instrumentation (01-03-2022)“…In this paper, an indirect flow pattern recognition method based on time-frequency analysis and neural networks is proposed to investigate the flow patterns in…”
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16
Determine Frequency Adjustment Reserve Based on AGC Regulation Capacity Demand’s Random Fuzzy Model
Published in MATEC Web of Conferences (01-01-2018)“…The uncertainty of wind power has a negative impact on the frequency adjustment of the system, so the frequency fluctuation caused by wind power can be…”
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Journal Article Conference Proceeding -
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Research on Economics of Mixed Energy Storage for Smoothing Wind Power Fluctuation with Consideration of Confidence Level
Published in MATEC Web of Conferences (01-01-2018)“…This paper proposes a research method for mitigating wind power fluctuations in a hybrid energy storage system considering the confidence level of wind power…”
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Journal Article Conference Proceeding -
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CIAM: An adaptive 2-in-1 missing data estimation algorithm in wireless sensor networks
Published in 2013 19th IEEE International Conference on Networks (ICON) (01-12-2013)“…In wireless sensor networks, missing sensor data is inevitable due to the inherent characteristic of wireless sensor networks, and it causes many difficulties…”
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Conference Proceeding -
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Structure-Guided and Phage-Assisted Evolution of Therapeutic Antibodies to Reverse On-Target Point Mutation-Mediated Resistance
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Resistance to therapeutic antibodies caused by on-target point mutations is a major obstacle in anticancer therapy, creating an "unmet clinical need." To…”
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Probing Queries in Wireless Sensor Networks
Published in 2008 The 28th International Conference on Distributed Computing Systems (01-06-2008)“…For queries in wireless sensor networks, empty sets may be returned as query results which could confuse users a lot and users obtain no useful information…”
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Conference Proceeding