Search Results - "Pan, Jonathan Z."

Differential general anesthetic effects on microglial cytokine expression by Ye, Xuefei, Lian, Qingquan, Eckenhoff, Maryellen F, Eckenhoff, Roderic G, Pan, Jonathan Z

“…Post-operative cognitive dysfunction has been widely observed, especially in older patients. An association of post-operative cognitive dysfunction with the…”
Get full text

Expert-augmented automated machine learning optimizes hemodynamic predictors of spinal cord injury outcome by Chou, Austin, Torres-Espin, Abel, Kyritsis, Nikos, Huie, J Russell, Khatry, Sarah, Funk, Jeremy, Hay, Jennifer, Lofgreen, Andrew, Shah, Rajiv, McCann, Chandler, Pascual, Lisa U, Amorim, Edilberto, Weinstein, Philip R, Manley, Geoffrey T, Dhall, Sanjay S, Pan, Jonathan Z, Bresnahan, Jacqueline C, Beattie, Michael S, Whetstone, William D, Ferguson, Adam R

“…Artificial intelligence and machine learning (AI/ML) is becoming increasingly more accessible to biomedical researchers with significant potential to transform…”
Get full text

Topological network analysis of patient similarity for precision management of acute blood pressure in spinal cord injury by Torres-Espín, Abel, Haefeli, Jenny, Ehsanian, Reza, Torres, Dolores, Almeida, Carlos A, Huie, J Russell, Chou, Austin, Morozov, Dmitriy, Sanderson, Nicole, Dirlikov, Benjamin, Suen, Catherine G, Nielson, Jessica L, Kyritsis, Nikos, Hemmerle, Debra D, Talbott, Jason F, Manley, Geoffrey T, Dhall, Sanjay S, Whetstone, William D, Bresnahan, Jacqueline C, Beattie, Michael S, McKenna, Stephen L, Pan, Jonathan Z, Ferguson, Adam R

“…Predicting neurological recovery after spinal cord injury (SCI) is challenging. Using topological data analysis, we have previously shown that mean arterial…”
Get full text

Inhaled anesthetics elicit region-specific changes in protein expression in mammalian brain by Pan, Jonathan Z., Xi, Jin, Eckenhoff, Maryellen F., Eckenhoff, Roderic G.

“…Inhaled anesthetics bind specifically to many proteins in the mammalian brain. Within the subgroup of proteins whose activity is substantially modulated by…”
Get full text

Changes in the Bispectral Index in Response to Loss of Consciousness and No Somatic Movement to Nociceptive Stimuli in Elderly Patients by Yang, Ning, Yue, Yun, Pan, Jonathan, Zuo, Ming-Zhang, Shi, Yu, Zhou, Shu-Zhen, Peng, Wen-Ping, Gao, Jian-Dong

“…Background： Bispectral index （BIS） is considered very useful to guide anesthesia care in elderly patients, but its use is controversial for the evaluation of…”
Get full text

Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion by Pan, Jonathan Z., Ni, Li, Sodhi, Ajeet, Aguanno, Ann, Young, Wise, Hart, Ronald P.

“…Injury of the spinal cord leads to an inflammatory tissue response, probably mediated in part by cytokines. Because a common therapy for acute spinal cord…”
Get full text

Pathological CNS Autoimmune Disease Triggered by Traumatic Spinal Cord Injury: Implications for Autoimmune Vaccine Therapy by Jones, T. Bucky, Basso, D. Michele, Sodhi, Ajeet, Pan, Jonathan Z, Hart, Ronald P, MacCallum, Robert C, Lee, Sunhee, Whitacre, Caroline C, Popovich, Phillip G

“…Lymphocytes respond to myelin proteins after spinal cord injury (SCI) and may contribute to post-traumatic secondary degeneration. However, there is increasing…”
Get full text

Halothane Binding Proteome in Human Brain Cortex by Pan, Jonathan Z, Xi, Jin, Tobias, John W, Eckenhoff, Maryellen F, Eckenhoff, Roderic G

“…Inhaled anesthetics bind specifically to a wide variety of proteins in the brain. This set of proteins must include those that contribute to the physiological…”
Get full text

Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury by Burke, John F, Yue, John K, Ngwenya, Laura B, Winkler, Ethan A, Talbott, Jason F, Pan, Jonathan Z, Ferguson, Adam R, Beattie, Michael S, Bresnahan, Jacqueline C, Haefeli, Jenny, Whetstone, William D, Suen, Catherine G, Huang, Michael C, Manley, Geoffrey T, Tarapore, Phiroz E, Dhall, Sanjay S

“…Cervical spinal cord injury (SCI) is a devastating condition with very few treatment options. It remains unclear if early surgery correlated with conversion of…”
Get full text

Dexmedetomidine Exerts an Anti-inflammatory Effect via α2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice by Li, Rong, Lai, Ieng K., Pan, Jonathan Z., Zhang, Pengbo, Maze, Mervyn

“…BACKGROUND:Clinical studies have shown that dexmedetomidine ameliorates cognitive decline in both the postoperative and critical care settings. This study…”
Get full text

Diagnostic blood RNA profiles for human acute spinal cord injury by Kyritsis, Nikos, Torres-Espín, Abel, Schupp, Patrick G, Huie, J Russell, Chou, Austin, Duong-Fernandez, Xuan, Thomas, Leigh H, Tsolinas, Rachel E, Hemmerle, Debra D, Pascual, Lisa U, Singh, Vineeta, Pan, Jonathan Z, Talbott, Jason F, Whetstone, William D, Burke, John F, DiGiorgio, Anthony M, Weinstein, Philip R, Manley, Geoffrey T, Dhall, Sanjay S, Ferguson, Adam R, Oldham, Michael C, Bresnahan, Jacqueline C, Beattie, Michael S

“…Diagnosis of spinal cord injury (SCI) severity at the ultra-acute stage is of great importance for emergency clinical care of patients as well as for potential…”
Get full text

The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings by Talbott, Jason F, Whetstone, William D, Readdy, William J, Ferguson, Adam R, Bresnahan, Jacqueline C, Saigal, Rajiv, Hawryluk, Gregory W J, Beattie, Michael S, Mabray, Marc C, Pan, Jonathan Z, Manley, Geoffrey T, Dhall, Sanjay S

“…Previous studies that have evaluated the prognostic value of abnormal changes in signals on T2-weighted MRI scans of an injured spinal cord have focused on the…”
Get full text

Between a ROCK and an IR Place by Pan, Jonathan Z., Eckenhoff, Roderic G.

Get full text

Motor Evoked Potentials Correlate With Magnetic Resonance Imaging and Early Recovery After Acute Spinal Cord Injury by Dhall, Sanjay S, Haefeli, Jenny, Talbott, Jason F, Ferguson, Adam R, Readdy, William J, Bresnahan, Jacqueline C, Beattie, Michael S, Pan, Jonathan Z, Manley, Geoffrey T, Whetstone, William D

“…Abstract BACKGROUND While the utilization of neurophysiologic intraoperative monitoring with motor evoked potentials (MEPs) has become widespread in surgery…”
Get full text

Correction: Expert-augmented automated machine learning optimizes hemodynamic predictors of spinal cord injury outcome by Chou, Austin, Torres-Espin, Abel, Kyritsis, Nikos, Huie, J. Russell, Khatry, Sarah, Funk, Jeremy, Hay, Jennifer, Lofgreen, Andrew, Shah, Rajiv, McCann, Chandler, Pascual, Lisa U, Amorim, Edilberto, Weinstein, Philip R, Manley, Geoffrey T, Dhall, Sanjay S, Pan, Jonathan Z, Bresnahan, Jacqueline C, Beattie, Michael S, Whetstone, William D, Ferguson, Adam R

“…[This corrects the article DOI: 10.1371/journal.pone.0265254.]…”
Get full text

Clinical Implementation of Novel Spinal Cord Perfusion Pressure Protocol in Acute Traumatic Spinal Cord Injury at U.S. Level I Trauma Center: TRACK-SCI Study by Yue, John K., Hemmerle, Debra D., Winkler, Ethan A., Thomas, Leigh H., Fernandez, Xuan Duong, Kyritsis, Nikolaos, Pan, Jonathan Z., Pascual, Lisa U., Singh, Vineeta, Weinstein, Philip R., Talbott, Jason F., Huie, J. Russell, Ferguson, Adam R., Whetstone, William D., Manley, Geoffrey T., Beattie, Michael S., Bresnahan, Jacqueline C., Mummaneni, Praveen V., Dhall, Sanjay S.

“…We sought to report the safety of implementation of a novel standard of care protocol using spinal cord perfusion pressure (SCPP) maintenance for managing…”
Get full text

Multidimensional Analysis of Magnetic Resonance Imaging Predicts Early Impairment in Thoracic and Thoracolumbar Spinal Cord Injury by Mabray, Marc C, Talbott, Jason F, Whetstone, William D, Dhall, Sanjay S, Phillips, David B, Pan, Jonathan Z, Manley, Geoffrey T, Bresnahan, Jacqueline C, Beattie, Michael S, Haefeli, Jenny, Ferguson, Adam R

“…Literature examining magnetic resonance imaging (MRI) in acute spinal cord injury (SCI) has focused on cervical SCI. Reproducible systems have been developed…”
Get more information

Genomics and Proteomic Techniques by Pan, Jonathan Z

“…Although general anesthesia induced by inhaled anesthetics produces definitive phenotypes (e.g., loss of mobility, amnesia, analgesia), the underlying targets…”
Get more information

Complications and outcomes of vasopressor usage in acute traumatic central cord syndrome by Readdy, William J, Whetstone, William D, Ferguson, Adam R, Talbott, Jason F, Inoue, Tomoo, Saigal, Rajiv, Bresnahan, Jacqueline C, Beattie, Michael S, Pan, Jonathan Z, Manley, Geoffrey T, Dhall, Sanjay S

“…OBJECT The optimal mean arterial pressure (MAP) for spinal cord perfusion after trauma remains unclear. Although there are published data on MAP goals after…”
Get full text

Injury volume extracted from MRI predicts neurologic outcome in acute spinal cord injury: A prospective TRACK-SCI pilot study by Mummaneni, Nikhil, Burke, John F., DiGiorgio, Anthony M., Thomas, Leigh H., Duong-Fernandez, Xuan, Harris, Mark, Pascual, Lisa U., Ferguson, Adam R., Russell Huie, J., Pan, Jonathan Z., Hemmerle, Debra D., Singh, Vineeta, Torres-Espin, Abel, Omondi, Cleopa, Kyritsis, Nikos, Weinstein, Phillip R., Whetstone, William D., Manley, Geoffrey T., Bresnahan, Jacqueline C., Beattie, Michael S., Cohen-Adad, Julien, Dhall, Sanjay S., Talbott, Jason F.

“…•The volume of MRI lesions after SCI predicts injury severity.•The degree of correlation of injury severity with MRI volume is greater than two-dimensional…”
Get full text