Search Results - "Pan, Jianbo"
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Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
Published in Nature communications (01-12-2020)“…Inter-tumor heterogeneity is a result of genomic, transcriptional, translational, and post-translational molecular features. To investigate the roles of…”
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Importin 7 enhances protective autophagy induced by nuclear translocation of homeobox A10 in oral squamous cell carcinoma
Published in Cellular and Molecular Biology (31-03-2024)“…Oral squamous cell carcinoma (OSCC) is a common malignant tumor. Importin7 (IPO7) is responsible for nucleoplasmic transport of RNAs and proteins, and it has…”
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Identification of Serological Biomarkers for Early Diagnosis of Lung Cancer Using a Protein Array-Based Approach
Published in Molecular & cellular proteomics (01-12-2017)“…Lung cancer (LC) remains the leading cause of mortality from malignant tumors worldwide. Currently, a lack of serological biomarkers for early LC diagnosis is…”
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Human umbilical cord mesenchymal stem cell exosome-derived miR-874-3p targeting RIPK1/PGAM5 attenuates kidney tubular epithelial cell damage
Published in Cellular & molecular biology letters (07-02-2023)“…Kidney insults due to various pathogenic factors, such as trauma, infection, and inflammation, can cause tubular epithelial cell injury and death, leading to…”
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Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitor cells
Published in Scientific reports (26-10-2021)“…The mechanisms underlying retinal development have not been completely elucidated. Extracellular vesicles (EVs) are novel essential mediators of cell-to-cell…”
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Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins
Published in Cell stem cell (07-09-2017)“…Zika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV interacts with the host molecular machinery to impact…”
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Integrated Proteomic and Glycoproteomic Characterization of Human High-Grade Serous Ovarian Carcinoma
Published in Cell reports (Cambridge) (20-10-2020)“…Many gene products exhibit great structural heterogeneity because of an array of modifications. These modifications are not directly encoded in the genomic…”
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Long-term dam behavior prediction with deep learning on graphs
Published in Journal of computational design and engineering (01-08-2022)“…Abstract Dam displacement prediction is one of the most crucial considerations for ensuring the dam’s long-term safe operation. Most existing models focus on…”
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Temperature and species-dependent regulation of browning in retrobulbar fat
Published in Scientific reports (04-02-2021)“…Retrobulbar fat deposits surround the posterior retina and optic nerve head, but their function and origin are obscure. We report that mouse retrobulbar fat is…”
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GeTeSEPdb: A comprehensive database and online tool for the identification and analysis of gene profiles with temporal-specific expression patterns
Published in Computational and structural biotechnology journal (01-12-2024)“…Gene expression is dynamic and varies at different stages of processes. The identification of gene profiles with temporal-specific expression patterns can…”
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Natural product P57 induces hypothermia through targeting pyridoxal kinase
Published in Nature communications (26-09-2023)“…Induction of hypothermia during hibernation/torpor enables certain mammals to survive under extreme environmental conditions. However, pharmacological…”
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Pattern Genes Suggest Functional Connectivity of Organs
Published in Scientific reports (26-05-2016)“…Human organ, as the basic structural and functional unit in human body, is made of a large community of different cell types that organically bound together…”
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Proteomic signatures of 16 major types of human cancer reveal universal and cancer-type-specific proteins for the identification of potential therapeutic targets
Published in Journal of hematology and oncology (07-12-2020)“…Proteomic characterization of cancers is essential for a comprehensive understanding of key molecular aberrations. However, proteomic profiling of a large…”
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Multiplexed Biomarker Panels Discriminate Zika and Dengue Virus Infection in Humans
Published in Molecular & cellular proteomics (01-02-2018)“…Zika virus (ZIKV) and dengue virus (DENV) are closely related flaviviruses that cause widespread, acute febrile illnesses, notably microcephaly for fetuses of…”
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A novel in vitro prognostic model of bladder cancer based on urine-derived living tumor cells
Published in Genes & diseases (01-11-2023)“…Bladder cancer (BLCA) remains a difficult malignancy to manage because of its high recurrence, intense follow-up, and invasive diagnostic and treatment…”
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MK-2206 Alleviates Renal Fibrosis by Suppressing the Akt/mTOR Signaling Pathway In Vivo and In Vitro
Published in Cells (Basel, Switzerland) (05-11-2022)“…Renal fibrosis is a common pathological feature of various kidney diseases, leading to irreversible renal failure and end-stage renal disease. However, there…”
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Integrative multi-omics and drug–response characterization of patient-derived prostate cancer primary cells
Published in Signal transduction and targeted therapy (01-05-2023)“…Prostate cancer (PCa) is the second most prevalent malignancy in males across the world. A greater knowledge of the relationship between protein abundance and…”
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An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication
Published in Genomics, proteomics & bioinformatics (01-02-2021)“…The Zika virus (ZIKV) and dengue virus (DENV) flaviviruses exhibit similar replicative processes but have distinct clinical outcomes. A systematic…”
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Effect of Cu(II) on degradation and decolorization of rhodamine B in subcritical water
Published in Chemical research in Chinese universities (01-08-2017)“…In this paper, subcritical water, an environmentally friendly solvent, was employed to degrade rhodamine B, which served as a model dye in textile industrial…”
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