Search Results - "Pan, Hongqiu"
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A risk score for prediction of poor treatment outcomes among tuberculosis patients with diagnosed diabetes mellitus from eastern China
Published in Scientific reports (27-05-2021)“…Persons living with diabetes (PLWD) with newly diagnosed tuberculosis are at greater risk of poor treatment outcomes. Identifying and prioritizing high-risk…”
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Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study
Published in Frontiers in genetics (23-10-2024)“…Objective The pathogenesis of antituberculosis drug-induced liver injury (AT-DILI) remains largely unknown. The current investigation aimed to determine the…”
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Clinical Characteristics of COVID-19 Patients With Pre-existing Hepatitis B Virus Infection: A Multicenter Report
Published in The American journal of gastroenterology (01-02-2021)“…Of the 99 patients with COVID-19 in Wuhan, 43 (43.4%) had differing degrees of liver function abnormality (1). [...]liver disease in COVID-19 attracted…”
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High accuracy of recombinant fusion protein early secretory antigenic target protein 6‐culture filtrate protein 10 skin test for the detection of tuberculosis infection: a phase III, multi‐centered, double‐blind, hospital‐based, randomized controlled trial
Published in International journal of infectious diseases (01-01-2023)“…•Early secretory antigenic target protein 6-culture filtrate protein 10 (EC) skin test is a phase III clinical trial. We validated its accuracy for…”
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Is tuberculosis treatment really free in China? A study comparing two areas with different management models
Published in PloS one (20-05-2015)“…China has implemented a free-service policy for tuberculosis. However, patients still have to pay a substantial proportion of their annual income for treatment…”
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A prospective multicenter clinical research study validating the effectiveness and safety of a chest X-ray-based pulmonary tuberculosis screening software JF CXR-1 built on a convolutional neural network algorithm
Published in Frontiers in medicine (15-08-2023)“…Background Chest radiography (chest X-ray or CXR) plays an important role in the early detection of active pulmonary tuberculosis (TB). In areas with a high TB…”
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Clustering and recent transmission of Mycobacterium tuberculosis in a Chinese population
Published in Infection and drug resistance (01-01-2018)“…The objectives of the present study were to characterize the clinical isolates prevailing in the northeast of Jiangsu and to investigate the mode of…”
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Genetic polymorphisms of UGT1A1 and susceptibility to anti-tuberculosis drug-induced liver: A RUCAM-based case–control study
Published in International journal of immunopathology and pharmacology (01-03-2018)“…Uridine 5’-diphospho-glucuronosyl-transferase 1A1 (UGT1A1) plays an important role in the biliary excretion of bilirubin, suggesting genetic polymorphisms of…”
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Fine mapping of genetic polymorphisms of pulmonary tuberculosis within chromosome 18q11.2 in the Chinese population: a case-control study
Published in BMC infectious diseases (22-10-2011)“…Recently, one genome-wide association study identified a susceptibility locus of rs4331426 on chromosome 18q11.2 for tuberculosis in the African population. To…”
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Changing Trajectories of Alanine Aminotransferase and Risk of Antituberculosis Drug‐Induced Liver Injury in Chinese Patients: A Cohort Study
Published in Journal of clinical pharmacology (01-07-2024)“…Antituberculosis drug‐induced liver injury (ATLI) is a major adverse effect during antituberculosis treatment. Early detection or prediction is essential to…”
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Glycemic Trajectories and Treatment Outcomes of Patients with Newly Diagnosed Tuberculosis: A Prospective Study in Eastern China
Published in American journal of respiratory and critical care medicine (01-08-2021)“…Patients with newly diagnosed tuberculosis often have inconsistent glycemic measurements during and after treatment. Distinct glycemic trajectories after the…”
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Multicenter analysis of clinical characteristics and outcomes in patients with COVID-19 who develop liver injury
Published in Journal of hepatology (01-08-2020)Get full text
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Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: a multicentre cohort study
Published in Gut (01-02-2021)Get more information
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Relationship between common telomere length‐related genetic variations, telomere length, and risk of antituberculosis drug‐induced hepatotoxicity in Chinese Han population: As assessed for causality using the updated Roussel Uclaf Causality Assessment Method
Published in Fundamental & clinical pharmacology (01-08-2023)“…Antituberculosis drug‐induced hepatotoxicity (ATDH) is a significant threat to tuberculosis control, and two recent studies indicated that leukocyte telomere…”
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Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population
Published in Pharmacogenetics and genomics (01-06-2019)“…OBJECTIVEAntituberculosis (anti-TB) drug-induced hepatotoxicity (ATDH) is a serious adverse drug reaction, and its pathogenic mechanism has not been elucidated…”
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Association between NR1I2 polymorphisms and susceptibility to anti-tuberculosis drug-induced hepatotoxicity in an Eastern Chinese Han population: A case-control study
Published in Infection, genetics and evolution (01-09-2020)“…Anti-tuberculosis drug-induced hepatotoxicity (ATDH) is a serious adverse drug reaction, and its pathogenic mechanism is still largely unknown. Pregnane X…”
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Heme oxygenase-1 and hemopexin gene polymorphisms and the risk of anti-tuberculosis drug-induced hepatotoxicity in China
Published in Pharmacogenomics (01-05-2022)“…To assess whether the risk of anti-tuberculosis drug-induced hepatotoxicity (ATDH) might be influenced by heme oxygenase-1 ( ) and hemopexin ( ) gene…”
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The role of the genetic variant FECH rs11660001 in the occurrence of anti‐tuberculosis drug‐induced liver injury
Published in Journal of clinical pharmacy and therapeutics (01-08-2022)“…What is known and objective The pathogenic mechanism of anti‐tuberculosis drug‐induced liver injury (AT‐DILI) is still largely unknown. Recent studies have…”
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Association between genetic polymorphisms of NRF2, KEAP1, MAFF, MAFK and anti-tuberculosis drug-induced liver injury: a nested case-control study
Published in Scientific reports (04-10-2019)“…Reactive metabolites of anti-tuberculosis (anti-TB) drugs can result in excessive reactive oxygen species (ROS), which are responsible for drug-induced liver…”
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Possible association of HMOX1 and NQO1 polymorphisms with anti‐tuberculosis drug‐induced liver injury: A matched case‐control study
Published in Journal of clinical pharmacy and therapeutics (01-08-2019)“…Summary What is known and objective Reactive metabolites from anti‐tuberculosis (anti‐TB) drugs can result in abnormal accumulation of reactive oxygen species…”
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