Search Results - "Pan, Dejing"
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Investigation of daughter cell dissection coincidence of single budding yeast cells immobilized in microfluidic traps
Published in Analytical and bioanalytical chemistry (01-03-2021)“…Microfluidic methodologies allow for automatic and high-throughput replicative lifespan (RLS) determination of single budding yeast cells. However, the…”
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A p53-based genetic tracing system to follow postnatal cardiomyocyte expansion in heart regeneration
Published in Development (Cambridge) (15-02-2017)“…In the field of heart regeneration, the proliferative potential of cardiomyocytes in postnatal mice is under intense investigation. However, solely relying on…”
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3
Interpretation of the Nobel Prize in Physiology or Medicine 2017
Published in Science China. Life sciences (01-01-2018)“…The announcement of the Nobel Prize in Physiology or Medicine 2017 gave us a mixture of excitement and surprise.Although researchers in circadian rhythm…”
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4
Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development
Published in Cell reports (Cambridge) (27-10-2015)“…RNA G-quadruplexes (G4s) play important roles in RNA biology. However, the function and regulation of mRNA G-quadruplexes in embryonic development remain…”
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5
A Bubble-Free Microfluidic Device for Easy-to-Operate Immobilization, Culturing and Monitoring of Zebrafish Embryos
Published in Micromachines (Basel) (28-02-2019)“…The development of miniaturized devices for studying zebrafish embryos has been limited due to complicated fabrication and operation processes. Here, we…”
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Functional consequences of a rare missense BARD1 c.403G>A germline mutation identified in a triple-negative breast cancer patient
Published in Breast cancer research : BCR (01-05-2021)“…We identified a rare missense germline mutation in BARD1 (c.403G>A or p.Asp135Asn) as pathogenic using integrated genomics and transcriptomics profiling of…”
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7
The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis
Published in Blood (03-05-2012)“…The DEAH helicase RHAU (alias DHX36, G4R1) is the only helicase shown to have G-quadruplex (G4)–RNA resolvase activity and the major source of G4-DNA resolvase…”
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A high-throughput microfluidic diploid yeast long-term culturing (DYLC) chip capable of bud reorientation and concerted daughter dissection for replicative lifespan determination
Published in Journal of nanobiotechnology (31-03-2022)“…Budding yeast, Saccharomyces cerevisiae, has been extensively favored as a model organism in aging and age-related studies, thanks to versatile microfluidic…”
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9
Multiple sgRNAs facilitate base editing-mediated i-stop to induce complete and precise gene disruption
Published in Protein & cell (01-11-2019)Get full text
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10
Normal erythropoiesis but severe polyposis and bleeding anemia in Smad4-deficient mice
Published in Blood (15-10-2007)“…The tumor suppressor Smad4 mediates signaling by the transforming growth factor beta (TGF-β) superfamily of ligands. Previous studies showed that several TGF-β…”
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Recent advances of integrated microfluidic systems for fungal and bacterial analysis
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-01-2023)“…Precise manipulation, fast cultivation, and sensitive detection of fungi and bacteria are vital for behavior monitoring, phenotypic identification, physiology…”
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12
Using microfluidic impedance cytometry to measure C. elegans worms and identify their developmental stages
Published in Sensors and actuators. B, Chemical (01-12-2018)“…An animation showing the working principle of CeMIC: measuring a flow-through C. elegans worm via electrical impedance spectroscopy, identifying its…”
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13
Nucleophosmin 1 promotes mucosal immunity by supporting mitochondrial oxidative phosphorylation and ILC3 activity
Published in Nature immunology (01-09-2024)“…Nucleophosmin 1 (NPM1) is commonly mutated in myelodysplastic syndrome (MDS) and acute myeloid leukemia. Concurrent inflammatory bowel diseases (IBD) and MDS…”
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14
Multiplexing microelectrodes for dielectrophoretic manipulation and electrical impedance measurement of single particles and cells in a microfluidic device
Published in Electrophoresis (01-05-2019)“…This work presents a microfluidic device, which was patterned with (i) microstructures for hydrodynamic capture of single particles and cells, and (ii)…”
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Investigation of geometry-dependent sensing characteristics of microfluidic electrical impedance spectroscopy through modeling and simulation
Published in Sensors and actuators. B, Chemical (01-11-2016)“…Microfluidic electrical impedance spectroscopy (EIS) has been widely used for the identification of single cells based on the detection of cell size or…”
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A microfluidic single-cell array for in situ laminar-flow-based comparative culturing of budding yeast cells
Published in Talanta (Oxford) (15-08-2021)“…To facilitate in situ comparative culturing of budding yeast cells in a precisely controlled microenvironment, we developed a microfluidic single-cell array…”
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Targeted Gene Delivery to Macrophages by Biodegradable Star-Shaped Polymers
Published in ACS applied materials & interfaces (17-02-2016)“…In this report, two biodegradable star-shaped polyasparamide derivatives and four analogues modified with either mannose or folic acid moiety for preferential…”
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Design and 3D modeling investigation of a microfluidic electrode array for electrical impedance measurement of single yeast cells
Published in Electrophoresis (01-10-2021)“…High‐resolution microscopic imaging may cause intensive image processing and potential impact of light irradiation on yeast replicative lifespan (RLS)…”
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19
Correlated evolution between CK1δ Protein and the Serine-rich Motif Contributes to Regulating the Mammalian Circadian Clock
Published in The Journal of biological chemistry (06-01-2017)“…Understanding the mechanism underlying the physiological divergence of species is a long-standing issue in evolutionary biology. The circadian clock is a…”
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20
Functional consequences of a rare missense BARD1 c.403GA germline mutation identified in a triple-negative breast cancer patient
Published in Breast cancer research : BCR (01-05-2021)“…We identified a rare missense germline mutation in BARD1 (c.403G>A or p.Asp135Asn) as pathogenic using integrated genomics and transcriptomics profiling of…”
Get full text
Journal Article