Search Results - "Pan, Chun‐Hao"

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer by Escobar-Hoyos, Luisa F., Penson, Alex, Kannan, Ram, Cho, Hana, Pan, Chun-Hao, Singh, Rohit K., Apken, Lisa H., Hobbs, G. Aaron, Luo, Renhe, Lecomte, Nicolas, Babu, Sruthi, Pan, Fong Cheng, Alonso-Curbelo, Direna, Morris, John P., Askan, Gokce, Grbovic-Huezo, Olivera, Ogrodowski, Paul, Bermeo, Jonathan, Saglimbeni, Joseph, Cruz, Cristian D., Ho, Yu-Jui, Lawrence, Sharon A., Melchor, Jerry P., Goda, Grant A., Bai, Karen, Pastore, Alessandro, Hogg, Simon J., Raghavan, Srivatsan, Bailey, Peter, Chang, David K., Biankin, Andrew, Shroyer, Kenneth R., Wolpin, Brian M., Aguirre, Andrew J., Ventura, Andrea, Taylor, Barry, Der, Channing J., Dominguez, Daniel, Kümmel, Daniel, Oeckinghaus, Andrea, Lowe, Scott W., Bradley, Robert K., Abdel-Wahab, Omar, Leach, Steven D.

“…Pancreatic ductal adenocarcinoma (PDAC) is driven by co-existing mutations in KRAS and TP53. However, how these mutations collaborate to promote this cancer is…”
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Keratin 17 identifies the most lethal molecular subtype of pancreatic cancer by Roa-Peña, Lucia, Leiton, Cindy V., Babu, Sruthi, Pan, Chun-Hao, Vanner, Elizabeth A., Akalin, Ali, Bandovic, Jela, Moffitt, Richard A., Shroyer, Kenneth R., Escobar-Hoyos, Luisa F.

“…Although the overall five-year survival of patients with pancreatic ductal adenocarcinoma (PDAC) is dismal, there are survival differences between cases with…”
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Neutralizing activity to SARS‐CoV‐2 of convalescent and control plasma used in a randomized controlled trial by Freedenberg, Alex T., Pan, Chun‐Hao, Diehl, William E., Romeiser, Jamie L., Hwang, Ga‐Ram, Leiton, Cindy V., Muecksch, Frauke, Shroyer, Kenneth R., Bennett‐Guerrero, Elliott

“…Background There are limited data on the neutralizing activity of convalescent plasma (CP) administered in randomized controlled trials (RCT) of COVID‐19…”
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Dihydroceramide desaturase 1 (DES1) promotes anchorage‐independent survival downstream of HER2‐driven glucose uptake and metabolism by Linzer, Ryan W., Guida, Danielle L., Aminov, Jonathan, Snider, Justin M., Khalife, Gabrielle, Buyukbayraktar, A. Burak, Alhaddad, Charbel, Resnick, Andrew E., Wang, Pule, Pan, Chun‐Hao, Allopenna, Janet J., Clarke, Christopher J.

“…Oncogenic reprogramming of cellular metabolism is a hallmark of many cancers, but our mechanistic understanding of how such dysregulation is linked to tumor…”
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Vorinostat enhances the cisplatin-mediated anticancer effects in small cell lung cancer cells by Pan, Chun-Hao, Chang, Ying-Fang, Lee, Ming-Shuo, Wen, B-Chen, Ko, Jen-Chung, Liang, Sheng-Kai, Liang, Mei-Chih

“…Vorinostat, a histone deacetylase (HDAC) inhibitor, is a promising agent for cancer therapy. Combining vorinostat with cisplatin may relax the chromatin…”
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An unbiased high‐throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer by Pan, Chun‐Hao, Otsuka, Yuka, Sridharan, BanuPriya, Woo, Melissa, Leiton, Cindy V., Babu, Sruthi, Torrente Gonçalves, Mariana, Kawalerski, Ryan R., K. Bai, Ji Dong, Chang, David K., Biankin, Andrew V., Scampavia, Louis, Spicer, Timothy, Escobar‐Hoyos, Luisa F., Shroyer, Kenneth R.

“…Pancreatic ductal adenocarcinoma (PDAC) is predicted to become the second leading cause of cancer‐related deaths in the United States by 2020, due in part to…”
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Surgical treatment of isolated zygomatic fracture: Outcome comparison between titanium plate and bioabsorbable plate by Wu, Chao-Ming, Chen, Ying-An, Liao, Han-Tsung, Chen, Chih-hao, Pan, Chun–Hao, Chen, Chien-Tzung

“…Summary Background Zygoma fracture is of clinical importance because malar prominence plays an essential role in facial appearance. Traditionally, most…”
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Penalized full likelihood approach to variable selection for Cox’s regression model under nested case–control sampling by Wang, Jie-Huei, Pan, Chun-Hao, Chang, I-Shou, Hsiung, Chao Agnes

“…Assuming Cox’s regression model, we consider penalized full likelihood approach to conduct variable selection under nested case–control (NCC) sampling…”
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Prognostic Factors for Attempted Finger Replantation and Revascularisation after Traumatic Amputation: A 16-Year Retrospective Cohort Study by Lu, Yi-Min, Lin, Yu-Te, Tsai, Chia-Hsuan, Pan, Chun-Hao, Chen, Hsin-Hung, Lee, Min-Chao

“…The aim of this study was to evaluate the impact of variant factors on finger replantation and revascularisation after traumatic amputation, which also…”
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Depression and pain: An appraisal of cost effectiveness and cost utility of antidepressants by Pan, Yi-Ju, Pan, Chun-Hao, Chan, Hung-Yu, Kuo, Kuei-Hong

“…Abstract Background Although depression and chronic pain frequently co-occur, there is a lack of clarity in the literature regarding the cost-effectiveness and…”
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Dissecting the Oncogenic Roles of Keratin 17 in the Hallmarks of Cancer by Baraks, Gabriella, Tseng, Robert, Pan, Chun-Hao, Kasliwal, Saumya, Leiton, Cindy V, Shroyer, Kenneth R, Escobar-Hoyos, Luisa F

“…There is an unmet need to identify and validate tumor-specific therapeutic targets to enable more effective treatments for cancer. Heterogeneity in patient…”
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Alveolar Differentiation Drives Resistance to KRAS Inhibition in Lung Adenocarcinoma by Li, Zhuxuan, Zhuang, Xueqian, Pan, Chun-Hao, Yan, Yan, Thummalapalli, Rohit, Hallin, Jill, Torborg, Stefan, Singhal, Anupriya, Chang, Jason C, Manchado, Eusebio, Dow, Lukas E, Yaeger, Rona, Christensen, James G, Lowe, Scott W, Rudin, Charles M, Joost, Simon, Tammela, Tuomas

“…Lung adenocarcinoma (LUAD), commonly driven by KRAS mutations, is responsible for 7% of all cancer mortality. The first allele-specific KRAS inhibitors were…”
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The PHLPP2 phosphatase is a druggable driver of prostate cancer progression by Nowak, Dawid G, Katsenelson, Ksenya Cohen, Watrud, Kaitlin E, Chen, Muhan, Mathew, Grinu, D'Andrea, Vincent D, Lee, Matthew F, Swamynathan, Manojit Mosur, Casanova-Salas, Irene, Jibilian, Megan C, Buckholtz, Caroline L, Ambrico, Alexandra J, Pan, Chun-Hao, Wilkinson, John E, Newton, Alexandra C, Trotman, Lloyd C

“…Metastatic prostate cancer commonly presents with targeted, bi-allelic mutations of the and tumor suppressor genes. In contrast, however, most candidate tumor…”
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Targeting Keratin 17 in Pancreatic Cancer: A Novel Rewired Pathway of Nucleotide Metabolism that Drives Chemoresistance by Pan, Chun‐Hao, Tseng, Robert, Donnelly, Katie, Leiton, Cindy V., Hogg, Simon J., Marchenko, Natalia, Singh, Pankaj K., Shroyer, Kenneth R., Escobar‐Hoyos, Luisa F.

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by two molecular subtypes, of which the basal‐like subtype is associated with the worst survival and…”
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Application of Computer-Assisted Navigation System in Acute Zygomatic Fractures by Yang, Cristhiam, Lee, Min-Chao, Pan, Chun-Hao, Chen, Chih-hao, Chen, Chien-Tzung

“…OBJECTIVETo compare the surgical results of early treatment of zygomatic fractures with and without the use of the computer-assisted navigation system…”
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Surgical Decompression or Corticosteroid Treatment of Indirect Traumatic Optic Neuropathy: A Randomized Controlled Trial by Chen, Hsin-Hung, Lee, Min-Chao, Tsai, Chia-Hsuan, Pan, Chun-Hao, Lin, Yu-Te, Chen, Chien-Tzung

“…BACKGROUNDTraumatic optic neuropathy (TON) is a rare cause of severe permanent visual impairment after injury. Traumatic optic neuropathy may occur due to…”
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Clinical outcomes for minimally invasive primary and secondary orbital reconstruction using an advanced synergistic combination of navigation and endoscopy by Chen, Chien-Tzung, Pan, Chun-Hao, Chen, Chih-Hao, Shyu, Victor Bong-Han, Wu, John Chung-Han, Kang, Gavin Chun-Wui

“…Sequelae of inadequate orbital reconstruction include enophthalmos, hypoglobus, and diplopia. Accuracy of orbital reconstruction is largely subjective and…”
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Surgical Timing and Fracture Type on the Outcome of Diplopia After Orbital Fracture Repair by Yu, De-Yi, Chen, Chih-Hao, Tsay, Pei-Kwei, Leow, Aik-Ming, Pan, Chun-Hao, Chen, Chien-Tzung

“…BACKGROUNDOrbital fractures and the concomitant soft tissue injuries within the bony orbit result in well-recognized complications such as diplopia and…”
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The role of preliminary hospitals in the management of a mass burn casualty disaster by Kuo, Ling-Wei, Yen, Cheng-I, Fu, Chih-Yuan, Pan, Chun-Hao, Hsu, Chih-Po, Hsiao, Yen-Chang, Hsieh, Chi-Hsun, Hsu, Yu-Pao

“…•The Formosa Fun Coast explosion is an internationally-known event.•There were 495 total casualties, 253 had 2nd or 3rd degree burns.•We retrospectively…”
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Combined Intraoral and Endoscopic Approach for Malar Reduction by Chen, Chien-Tzung, Pan, Chun-Hao, Liao, Han-Tsung, Chen, Yu Ray, Kang, Gavin Chun-Wui

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