Search Results - "Pan, Chaohu"

Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription by Yang, Liping, Chen, Shengchuan, Zhao, Qun, Pan, Chaohu, Peng, Linan, Han, Yu, Li, Lili, Ruan, Jiayin, Xia, Jingyan, Yang, Heng, Xu, Feng, Cheng, Genhong

“…[Display omitted] It is well known that interferon (IFN)-α/-β activates the JAK/STAT signaling pathway and suppresses viral replication through the induction…”
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Systematic assessment and optimizing algorithm of tumor mutational burden calculation and their implications in clinical decision-making by Sun, Daqiang, Xu, Meilin, Pan, Chaohu, Tang, Hongzhen, Wang, Peng, Wu, Dongfang, Luo, Haitao

“…Tumor mutation burden (TMB) has been validated as a biomarker to predict the response of immune checkpoint inhibitors (ICIs) treatment in various cancers…”
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Isolation, identification, and environmental adaptability of heavy-metal-resistant bacteria from ramie rhizosphere soil around mine refinery by Jiang, Jie, Pan, Chaohu, Xiao, Aiping, Yang, Xiai, Zhang, Guimin

“…Six bacteria strains from heavy-metal-polluted ramie rhizosphere soil were isolated through Cd 2+ stress, which were numbered as JJ1, JJ2, JJ10, JJ11, JJ15,…”
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Predicting Durable Responses to Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer Using a Multi-Feature Model by Wang, Lei, Zhang, Hongbing, Pan, Chaohu, Yi, Jian, Cui, Xiaoli, Li, Na, Wang, Jiaqian, Gao, Zhibo, Wu, Dongfang, Chen, Jun, Jiang, Jizong, Chu, Qian

“…Due to the complex mechanisms affecting anti-tumor immune response, a single biomarker is insufficient to identify patients who will benefit from immune…”
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Homeoprotein SIX1 compromises antitumor immunity through TGF-β-mediated regulation of collagens by Liu, Wancheng, Gao, Meiling, Li, Lili, Chen, Yu, Fan, Huimin, Cai, Qiaomei, Shi, Yueyue, Pan, Chaohu, Liu, Junxiao, Cheng, Lucy S., Yang, Heng, Cheng, Genhong

“…The tumor microenvironment (TME), including infiltrated immune cells, is known to play an important role in tumor growth; however, the mechanisms underlying…”
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An enhanced genetic mutation-based model for predicting the efficacy of immune checkpoint inhibitors in patients with melanoma by Pan, Chaohu, Tang, Hongzhen, Wang, Wei, Wu, Dongfang, Luo, Haitao, Xu, Libin, Lin, Xue-Jia

“…Programmed death ligand 1 (PD-L1) and tumor mutation burden (TMB) have been developed as biomarkers for the treatment of immune checkpoint inhibitors (ICIs)…”
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Integrated investigation of the prognostic role of HLA LOH in advanced lung cancer patients with immunotherapy by Zhang, Xiaotao, Tang, Hongzhen, Luo, Haitao, Lu, Huiping, Pan, Chaohu, Yu, Haiming, Zhang, Linlin, Guan, Yaping, Yu, Lan, Chu, Huili, Chen, Jun, Wang, Jun

“…Although multiple studies have shown that loss of heterozygosity (LOH) at the human leukocyte antigen (HLA) locus is one of the mechanisms of immune escape,…”
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Enhancing the HSV-1-mediated antitumor immune response by suppressing Bach1 by Pan, Chaohu, Cai, Qiaomei, Li, Xiaorong, Li, Lili, Yang, Liping, Chen, Yu, Liu, Junxiao, Liu, Wancheng, Gao, Meiling, Sui, Tianqi, Wang, Xiaoyang, Fan, Huiming, Ruan, Jiayin, Shi, Yueyue, Chen, Saihua, Cheng, Lucy S., Liu, Jiayong, Yang, Heng, Cheng, Genhong

“…Background In 2015, herpes simplex virus 1 (HSV-1)-derived talimogene laherparepvec (T-VEC) was the first oncolytic virus approved by the US Food and Drug…”
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Spatial multi-omics revealed the impact of tumor ecosystem heterogeneity on immunotherapy efficacy in patients with advanced non-small cell lung cancer treated with bispecific antibody by Song, Xinyu, Xiong, Anwen, Wu, Fengying, Li, Xuefei, Wang, Jing, Jiang, Tao, Chen, Peixin, Zhang, Xiaoshen, Zhao, Zhikai, Liu, Huifang, Cheng, Lei, Zhao, Chao, Wang, Zhehai, Pan, Chaohu, Cui, Xiaoli, Xu, Ting, Luo, Haitao, Zhou, Caicun

“…BackgroundImmunotherapy for malignant tumors has made great progress, but many patients do not benefit from it. The complex intratumoral heterogeneity (ITH)…”
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ADP-ribosyltransferase PARP11 suppresses Zika virus in synergy with PARP12 by Li, Lili, Shi, Yueyue, Li, Sirui, Liu, Junxiao, Zu, Shulong, Xu, Xin, Gao, Meiling, Sun, Nina, Pan, Chaohu, Peng, Linan, Yang, Heng, Cheng, Genhong

“…Zika virus (ZIKV) infection and ZIKV epidemic have been continuously spreading silently throughout the world and its associated microcephaly and other serious…”
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The Identification of Two RNA Modification Patterns and Tumor Microenvironment Infiltration Characterization of Lung Adenocarcinoma by He, Wan, Lin, Gengpeng, Pan, Chaohu, Li, Wenwen, Shen, Jing, Liu, Yangli, Li, Hui, Wu, Dongfang, Lin, Xuejia

“…RNA modification plays an important role in many diseases. A comprehensive study of tumor microenvironment (TME) characteristics mediated by RNA modification…”
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Corrigendum: The Identification of Two RNA Modification Patterns and Tumor Microenvironment Infiltration Characterization of Lung Adenocarcinoma by He, Wan, Lin, Gengpeng, Pan, Chaohu, Li, Wenwen, Shen, Jing, Liu, Yangli, Li, Hui, Wu, Dongfang, Lin, Xuejia

“…[This corrects the article DOI: 10.3389/fgene.2022.761681.]…”
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Interferon-stimulated gene PVRL4 broadly suppresses viral entry by inhibiting viral-cellular membrane fusion by Cai, Qiaomei, Sun, Nina, Zhang, Yurui, Wang, Jingfeng, Pan, Chaohu, Chen, Yu, Li, Lili, Li, Xiaorong, Liu, Wancheng, Aliyari, Saba R, Yang, Heng, Cheng, Genhong

“…Viral infection elicits the type I interferon (IFN-I) response in host cells and subsequently inhibits viral infection through inducing hundreds of…”
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Integrated tumor genomic and immune microenvironment analysis identifies predictive biomarkers associated with the efficacy of neoadjuvant therapy for triple‐negative breast cancer by Zhu, Yanhui, Zhang, Hongfei, Pan, Chaohu, He, Gao, Cui, Xiaoli, Yu, Xiafei, Zhang, Xiaoqiang, Wu, Dongfang, Yang, Junzhe, Wu, Xian, Luo, Haitao, Liu, Xiaoan

“…Background Although neoadjuvant chemotherapy (NAC) is currently the best therapy for triple‐negative breast cancer (TNBC), resistance still occurs in a…”
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Expression Patterns of Glycosylation Regulators Define Tumor Microenvironment and Immunotherapy in Gastric Cancer by Li, Fang, Huang, Kaibin, Pan, Chaohu, Xiao, Yajie, Zheng, Qijun, Zhong, Keli

“…Glycosylation (Glyc) is prevalently related to gastric cancer (GC) pathophysiology. However, studies on the relationship between glycosylation regulators and…”
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Integrated tumor genomic and immune microenvironment analysis identifies predictive biomarkers associated with the efficacy of neoadjuvant therapy for triple-negative breast cancer by Zhu, Yanhui, Pan, Chaohu, Zhang, Hongfei, He, Gao, Yu, Xiafei, Cui, Xiaoli, Yang, Junzhe, Zhang, Xiaoqiang, Gao, Edmond, Liu, Xiaoan

“…e12592 Background: Although neoadjuvant chemotherapy (NAC) is currently the best therapy for triple-negative breast cancer (TNBC), resistance still occurs in a…”
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Proteomic Profiling and Tumor Microenvironment Characterization Reveal Molecular and Immunological Hallmarks of Left-Sided and Right-Sided Colon Cancer Tumorigenesis by Hong, Zhu, Wang, Tao, Wang, Wei, Jing, Haoren, Tang, Hongzhen, Xu, Mingyue, Pan, Chaohu, Mu, Xiaojing, Zhang, Di, Gao, Guochao, Gao, Zihe, Luo, Haitao, Zhou, Yi

“…Left-sided and right-sided colon cancer (LSCC and RSCC) display different biological and clinical characteristics. However, the differences in their…”
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Serological markers associated with response and adverse events in patients of esophageal squamous carcinoma with toripalimab combined with nab-paclitaxel and S-1 as neoadjuvant therapy by Zhang, Guoqing, Yuan, Jing, Xu, Qing, Zhang, Jing, Liu, Minglu, Song, Zhigang, Wu, Liang Liang, Yang, Bo, Hu, Yi, Jiao, Shunchang, Luo, Haitao, Cui, Xiaoli, Pan, Chaohu

“…e16017 Background: Immune checkpoint inhibitor (ICI) combined with chemotherapy as a neoadjuvant therapy has been applied to the treatment of patients with…”
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Multi-omics analysis uncovers tumor ecosystem dynamics during neoadjuvant toripalimab plus nab-paclitaxel and S-1 for esophageal squamous cell carcinoma: a single-center, open-label, single-arm phase 2 trial by Zhang, Guoqing, Yuan, Jing, Pan, Chaohu, Xu, Qing, Cui, Xiaoli, Zhang, Jing, Liu, Minglu, Song, Zhigang, Wu, Liangliang, Wu, Dongfang, Luo, Haitao, Hu, Yi, Jiao, Shunchang, Yang, Bo

“…Immune checkpoint inhibitors combined with chemotherapy as a neoadjuvant therapy have been applied to the treatment of esophageal squamous cell carcinoma…”
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Total Neoadjuvant Therapy With PD-1 Blockade for High-Risk Proficient Mismatch Repair Rectal Cancer by Li, Yingjie, Pan, Chaohu, Gao, Yuye, Zhang, Li, Ji, Dengbo, Cui, Xiaoli, Zhang, Xiaoyan, Cai, Yong, Zhang, Yangzi, Yao, Yunfeng, Wang, Lin, Leng, Jiahua, Zhan, Tiancheng, Wu, Dongfang, Gao, Zhibo, Sun, Ying-Shi, Li, Zhongwu, Luo, Haitao, Wu, Aiwen

“…Total neoadjuvant therapy (TNT) is the standard treatment for locally advanced rectal cancer, especially for patients with high-risk factors. However, the…”
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