Search Results - "Pan, Caixu"

Tumor Immune Microenvironment Characterization in Hepatocellular Carcinoma Identifies Four Prognostic and Immunotherapeutically Relevant Subclasses by Gao, Xingxing, Huang, Hechen, Wang, Yubo, Pan, Caixu, Yin, Shengyong, Zhou, Lin, Zheng, Shusen

“…The tumor microenvironment (TME) plays a critical role in the pathogenesis of hepatocellular carcinoma (HCC). However, underlying compositions and functions…”
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Lenvatinib enhances antitumor immunity by promoting the infiltration of TCF1+ CD8+ T cells in HCC via blocking VEGFR2 by Mei, Zhibin, Gao, Xingxing, Pan, Caixu, Wu, Qinchuan, Wang, Shuai, Qian, Junjie, Xu, Zhentian, Xu, Kangdi, Zhou, Lin, Zhen, Shushen

“…Lenvatinib is the favorable treatment for advanced hepatocellular carcinoma (HCC), and it is currently undergoing phase III clinical trials. However, the…”
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Combination with Toll-like receptor 4 (TLR4) agonist reverses GITR agonism mediated M2 polarization of macrophage in Hepatocellular carcinoma by Pan, Caixu, Wu, Qinchuan, Wang, Shuai, Mei, Zhibin, Zhang, Lele, Gao, Xingxing, Qian, Junjie, Xu, Zhentian, Zhang, Ke, Su, Rong, Guo, Danjing, Zhou, Lin, Zheng, Shusen

“…The glucocorticoid-induced tumor necrosis factor receptor (GITR) agonistic antibody (DTA-1) has been proved to elicit robust immune response in various kinds…”
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Self-assembly nanovaccine containing TLR7/8 agonist and STAT3 inhibitor enhances tumor immunotherapy by augmenting tumor-specific immune response by Zhang, Lele, Huang, Jiacheng, Chen, Xiaona, Pan, Caixu, He, Yong, Su, Rong, Guo, Danjing, Yin, Shengyong, Wang, Shuai, Zhou, Lin, Chen, Jianxiang, Zheng, Shusen, Qiao, Yiting

“…BackgroundCancer vaccines are a promising strategy for cancer immunotherapy. Cancer vaccines elicits a specific cytotoxic immune response to tumor antigens…”
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Blocking CD47 promotes antitumour immunity through CD103+ dendritic cell–NK cell axis in murine hepatocellular carcinoma model by Wang, Shuai, Wu, Qinchuan, Chen, Tianchi, Su, Rong, Pan, Caixu, Qian, Junjie, Huang, Hechen, Yin, Shengyong, Xie, Haiyang, Zhou, Lin, Zheng, Shusen

“…The CD47–signal regulatory protein α (SIRPα) axis inhibits dendritic cell (DC) phagocytosis and contributes to immune evasion. However, the behaviour of DCs…”
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Disulfiram/Copper Induces Immunogenic Cell Death and Enhances CD47 Blockade in Hepatocellular Carcinoma by Gao, Xingxing, Huang, Hechen, Pan, Caixu, Mei, Zhibin, Yin, Shengyong, Zhou, Lin, Zheng, Shusen

“…Some chemotherapeutic agents have been found to enhance antitumor immunity by inducing immunogenic cell death (ICD). The combination of disulfiram (DSF) and…”
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Targeting neuropilin-1 abolishes anti-PD-1-upregulated regulatory T cells and synergizes with 4-1BB agonist for liver cancer treatment by Wu, Qinchuan, Pan, Caixu, Zhou, Yuan, Wang, Shuai, Xie, Liting, Zhou, Wuhua, Ding, Limin, Chen, Tianchi, Qian, Junjie, Su, Rong, Gao, Xingxing, Mei, Zhibin, Qiao, Yiting, Yin, Shengyong, Wu, Yi, Wang, Jieyi, Zhou, Lin, Zheng, Shusen

“…Regulatory T cells (Tregs) are an obstacle to PD-1 blockade-mediated antitumor efficacy. However, the behaviors of Tregs response to anti-PD-1 in HCC and the…”
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Nanosecond Pulsed Electric Field Induces an Antitumor Effect in Triple-Negative Breast Cancer via CXCL9 Axis Dependence in Mice by Xu, Zhentian, Pan, Caixu, Chen, Luyan, Qian, Junjie, Chen, Xinhua, Zhou, Lin, Zheng, Shusen

“…Triple-negative breast cancer (TNBC) is a refractory tumor, and therapeutic options are very limited. Local ablation has been applied recently. Chemokines play…”
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Nanosecond pulsed electric field stimulates CD103+ DC accumulation in tumor microenvironment via NK-CD103+ DC crosstalk by Qian, Junjie, Ding, Limin, Wu, Qinchuan, Yu, Xizhi, Li, Qiyong, Gu, Yangjun, Wang, Shuai, Mao, Jing, Liu, Xi, Li, Bohan, Pan, Caixu, Wang, Wenchao, Wang, Yubo, Liu, Jianpeng, Qiao, Yiting, Xie, Haiyang, Chen, Tianchi, Ge, Jiangzhen, Zhou, Lin, Yin, Shengyong, Zheng, Shusen

“…CD103+ DC is crucial for antitumor immune response. As a promising local therapy on cancers, nanosecond pulsed electric field (nsPEF) has been widely reported…”
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