Search Results - "Palomino, Gustavo Martelli"
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Bothrops jararaca and Bothrops erythromelas Snake Venoms Promote Cell Cycle Arrest and Induce Apoptosis via the Mitochondrial Depolarization of Cervical Cancer Cells
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…Bothrops jararaca (BJ) and Bothrops erythromelas (BE) are viper snakes found in South-Southeast and Northeast regions of Brazil, respectively. Snake venoms are…”
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HLA-G Expression in the Skin of Patients with Systemic Sclerosis
Published in Journal of rheumatology (01-06-2009)“…Objective. To determine HLA-G expression in skin biopsies from patients with systemic sclerosis (SSc), and its association with epidemiological, clinical, and…”
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Polymorphic sites at the 3' untranslated region of the HLA-G gene are associated with differential hla-g soluble levels in the Brazilian and French population
Published in PloS one (25-10-2013)“…HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows lower frequency of polymorphism at the coding region but higher…”
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Haplotypes of the HLA-G 3' Untranslated Region Respond to Endogenous Factors of HLA-G+ and HLA-G- Cell Lines Differentially
Published in PloS one (03-01-2017)“…The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in cancer invasion and acceptance of allografts. The 5' and 3' regulatory…”
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HLA‐G 3′ untranslated region polymorphic sites associated with increased HLA‐G production are more frequent in patients exhibiting differentiated thyroid tumours
Published in Clinical endocrinology (Oxford) (01-04-2017)“…Summary Background HLA‐G is a nonclassical class I histocompatibility molecule implicated on the immune escape mechanism of tumour cells. We evaluated the…”
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Immunohistochemical evaluation of HLA-G and FoxP3+ T regulatory cells in oral cavity and lower lip squamous cell carcinomas
Published in Brazilian oral research (01-01-2019)“…Human Leukocyte Antigen G (HLA-G) is a molecule involved in the tumor immunosuppression and also in the generation of regulatory T (Treg) cells, thus leading…”
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Patients with Systemic Sclerosis Present Increased DNA Damage Differentially Associated with DNA Repair Gene Polymorphisms
Published in Journal of rheumatology (01-03-2014)“…Patients with systemic sclerosis (SSc) exhibit increased toxicity when exposed to genotoxic agents. In our study, we evaluated DNA damage and polymorphic sites…”
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Gene Expression Profiles Stratified according to Type 1 Diabetes Mellitus Susceptibility Regions
Published in Annals of the New York Academy of Sciences (01-12-2008)“…The MHC region (6p21) aggregates the major genes that contribute to susceptibility to type 1 diabetes (T1D). Three additional relevant susceptibility regions…”
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Immune response and evasion mechanisms in lip carcinogenesis: An immunohistochemical study
Published in Archives of oral biology (01-02-2019)“…•We evaluated the immune response occurring in the lip precancerous and cancerous microenvironment.•PD-L1 and HLA-G are overexpressed at different stages of…”
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Polymorphisms at the IL17A and IL17RA Genes are Associated with Prognosis of Papillary Thyroid Carcinoma
Published in Archives of medical research (01-02-2022)“…Interleukin (IL)-17A has a dual role in tumor immunity, promotes anti-tumor responses and facilitates angiogenesis by interacting with IL-17 receptor A…”
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Genetic polymorphism in IL17RA induces susceptibility to Toxoplasma gondii infection in Brazilian pregnant women
Published in Acta tropica (01-11-2020)“…•The GG and AG genotypes were the most frequents in reactive pregnant women.•The rs2275913 polymorphism seems to modulate the expression of IL-17.•There is…”
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Immune response and evasion mechanisms in lip carcinogenesis: An immunohistochemical study
Published in Archives of oral biology (01-02-2019)“…Programmed death ligand-1 (PD-L1) and human leukocyte antigen-G (HLA-G) are considered immune checkpoint molecules that inhibit T-cell effectiveness,…”
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HLA-G 3'-untranslated region polymorphisms are associated with HTLV-1 infection, proviral load and HTLV-associated myelopathy/tropical spastic paraparesis development
Published in Journal of general virology (01-10-2016)“…Most human T-lymphotropic virus type 1 (HTLV-1)-infected patients remain asymptomatic throughout life. The factors associated with HTLV-1-associated…”
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DNA damage increase in peripheral neutrophils from patients with rheumatoid arthritis is associated with the disease activity and the presence of shared epitope
Published in Clinical and experimental rheumatology (01-03-2017)“…Neutrophils play a major role in rheumatoid arthritis (RA) pathogenesis. We aimed to evaluate if neutrophil DNA damage in RA patients is associated with the…”
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Expression of HLA-E molecules in the placental tissue of women infected with HIV-1 and uninfected women
Published in Placenta (Eastbourne) (01-01-2017)“…Abstract Introduction Expression of HLA-E molecule in the placental extravillous trophoblast is associated with immune system cell inhibition, resulting in…”
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The variant of CD11b, rs1143679 within ITGAM , is associated with systemic lupus erythematosus and clinical manifestations in Brazilian patients
Published in Human immunology (01-02-2014)“…Abstract Background/aims Immune responses mediated by complement receptors (CR) are impaired in patients with systemic lupus erythematosus (SLE). Regarding CR3…”
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Polymorphic Sites at the 3 Untranslated Region of the HLA-G Gene Are Associated with Differential hla-g Soluble Levels in the Brazilian and French Population: e71742
Published in PloS one (01-10-2013)“…HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows lower frequency of polymorphism at the coding region but higher…”
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Association of Interferon-gamma gene polymorphism (+874 T/A) with systemic sclerosis
Published in Disease markers (2009)Get full text
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Association of Interferon-gamma gene polymorphism (+874 T/A) with systemic sclerosis
Published in Disease markers (01-01-2009)Get full text
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