Search Results - "Palombo, Matthew S."
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Optimizing Size and Copy Number For PEG-fMLF (N-Formyl-methionyl-leucyl-phenylalanine) Nanocarrier Uptake by Macrophages
Published in Bioconjugate chemistry (01-01-2008)“…Curing HIV-1 infection has remained elusive because of low and fluctuating drug levels arising from poor absorption, the development of viral reservoirs and…”
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Journal Article -
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Design and evaluation of a CXCR4 targeting peptide 4DV3 as an HIV entry inhibitor and a ligand for targeted drug delivery
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2019)“…[Display omitted] The feasibility of utilizing the cell surface chemokine receptor CXCR4 for human immunodeficiency virus (HIV) entry inhibition and as an…”
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Journal Article -
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Colorectal delivery and retention of PEG-Amprenavir-Bac7 nanoconjugates—proof of concept for HIV mucosal pre-exposure prophylaxis
Published in Drug delivery and translational research (01-02-2016)“…Local delivery of anti-HIV drugs to the colorectal mucosa, a major site of HIV replication, and their retention within mucosal tissue would allow for a…”
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Journal Article -
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Multimeric peptide-based PEG nanocarriers with programmable elimination properties
Published in Biomaterials (01-10-2009)“…Abstract In the current study, the design, synthetic feasibility and biochemical characterization of biodegradable peptidic PEG-based nanocarriers are…”
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Journal Article -
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CXCR4 targeted peptide carriers for the inhibition of HIV and delivery of anti-viral drugs
Published 01-01-2013“…HIV-1 continues to be a major epidemic affecting the global population and responsible for millions of deaths annually. Despite the mortality of the virus,…”
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Dissertation