Search Results - "Palodetto, Bruna"
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SEMA3A partially reverses VEGF effects through binding to neuropilin-1
Published in Stem cell research (01-07-2017)“…Cross-talk between hematopoietic stem cells (HSCs) and bone marrow stromal cells (BMSCs) is essential for HSCs regulation and leukemogenesis. Studying bone…”
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2
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis
Published in Biochimica et biophysica acta. Molecular basis of disease (01-02-2017)“…New drug development for neoplasm treatment is nowadays based on molecular targets that participate in the disease pathogenesis and tumor phenotype. Herein, we…”
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3
Serine protease inhibitor kunitz-type 2 is downregulated in myelodysplastic syndromes and modulates cell-cell adhesion
Published in Stem cells and development (15-05-2014)“…Myelodysplastic syndromes (MDS) are clonal disorders involving hematopoietic stem cells (HSC) characterized by ineffective hematopoiesis. In addition to HSC…”
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4
MDR-1 and GST polymorphisms are involved in myelodysplasia progression
Published in Leukemia research (01-08-2013)“…Abstract Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal stem cell disorders characterized by abnormal hematopoietic differentiation and…”
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5
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway
Published in Biochimica et biophysica acta. Molecular basis of disease (01-02-2017)“…New drug development for neoplasm treatment is nowadays based on molecular targets that participate in the disease pathogenesis and tumor phenotype. Herein, we…”
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6
A Novel Antisense Long Noncoding RNA Modulates NR4A1 Protein Level in Myeloid Malignancies
Published in Blood (03-12-2015)“…Introduction: The advent of whole transcriptome sequencing technologies revealed that most of the human genome is transcribed, producing a large repertoire of…”
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7
Knockdown of HCK Reduces Cell Death and Erythroid Differentiation in Human CD34+ Hematopoietic Progenitor Cells
Published in Blood (03-12-2015)“…Myelodysplastic syndromes (MDS) are clonal disorders characterized by ineffective hematopoiesis and increased risk of transformation to acute myeloid leukemia…”
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8
BRD4 Short Isoform Is a Myelodysplasia Prognostic Marker Involved in Inappropriate DNA Damage Response
Published in Blood (06-12-2014)“…INTRODUCTION: Epigenetic pathways can regulate gene expression by controlling and interpreting chromatin modifications. BRD4 is a BET member of…”
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Hematopoietic Cell Kinase (HCK) Is Involved in Myelodysplastic Syndromes and Acute Leukemia Pathophysiology By Modulating PI3K Pathway and Enhancing Erythroid Differentiation
Published in Blood (06-12-2014)“…Introduction: Src family non-receptor tyrosine kinase regulates diverse cellular responses mainly by activating PI3K signaling, an important pathway that…”
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10
MDR-1 and GST Polymorphisms Are Involved in Myelodysplasia Progression
Published in Blood (18-11-2011)“…Abstract 3507 Drug-metabolizing enzymes are responsible for the metabolism of several chemotherapeutic agents and may be involved in resistance to…”
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Downregulation Of SPINT2 Expression In Stromal Cells From Myelodysplastic Syndrome Patients Increases HGF and SDF-1 Secretion and Promotes Cell-Cell Adhesion By Alteration In Integrin Expression
Published in Blood (15-11-2013)“…Myelodysplastic syndromes (MDS) are clonal disorders of hematopoietic stem cells (HSC) characterized by ineffective hematopoiesis. In addition to HSC defects,…”
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12
Hematopoietic Cell Kinase (HCK) Is Highly Expressed in Myelodysplastic Syndrome (MDS) and Regulates Proliferation, Cell Cycle Progression and Hematopoietic Differentiation
Published in Blood (16-11-2012)“…Abstract 3813 The pathogenesis of MDS is complex and remains elusive. The molecular characterization of this disease has been a tool to obtain a better…”
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13
Influência dos polimorfismos da glutationa s-transferase na ototoxicidade dos aminoglicosídeos Influence of glutathione s-transferase on the ototoxicity caused by aminoglycosides
Published in Brazilian journal of otorhinolaryngology (01-06-2010)“…O processo de morte e danos em células ciliadas devido à exposição ao ruído e ototoxinas parece ser mediado por espécies reativas de oxigênio. OBJETIVO:…”
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14
Influência dos polimorfismos da glutationa s-transferase na ototoxicidade dos aminoglicosídeos
Published in Brazilian journal of otorhinolaryngology (01-06-2010)Get full text
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15
Influence of glutathione s-transferase on the ototoxicity caused by aminoglycosides
Published in Brazilian journal of otorhinolaryngology (01-05-2010)“…The process of hair cell damage and death as a result of exposure to noise and ototoxins seems to be mediated by reactive oxygen species. Aim: To investigate…”
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16
Influência dos polimorfismos da glutationa s-transferase na ototoxicidade dos aminoglicosídeos
Published in Brazilian journal of otorhinolaryngology (01-06-2010)“…O processo de morte e danos em células ciliadas devido à exposição ao ruído e ototoxinas parece ser mediado por espécies reativas de oxigênio. OBJETIVO:…”
Get full text
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