Search Results - "Palmisiano, Neil"

Novel Mechanisms for Post-Transplant Maintenance Therapy in Acute Myeloid Leukemia by Manobianco, Steven A., Rakiewicz, Tara, Wilde, Lindsay, Palmisiano, Neil D.

“…Allogeneic stem cell transplantation has improved survival for patients with acute myeloid leukemia (AML), especially for patients with disease at high risk of…”
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Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results by Heuser, Michael, Palmisiano, Neil, Mantzaris, Ioannis, Mims, Alice, DiNardo, Courtney, Silverman, Lewis R., Wang, Eunice S., Fiedler, Walter, Baldus, Claudia, Schwind, Sebastian, Pardee, Timothy, Perl, Alexander E., Cai, Charles, Kaulfuss, Stefan, Lagkadinou, Eleni, Rentzsch, Christine, Wagner, Markus, Wilkinson, Gary, Wu, Bingyan, Jeffers, Michael, Genvresse, Isabelle, Krämer, Alwin

“…The mutant IDH1 (mIDH1) inhibitor BAY1436032 demonstrated robust activity in preclinical AML models, supporting clinical evaluation. In the current…”
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Caring for AML Patients During the COVID-19 Crisis: An American and Italian Experience by Wilde, Lindsay, Isidori, Alessandro, Keiffer, Gina, Palmisiano, Neil, Kasner, Margaret

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent pandemic have impacted every aspect of oncology care…”
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The prognostic impact of cigarette smoking on survival in acute myeloid leukemia with TP53 mutations and/or 17p deletions by Bi, Xia, French, Zachary, Palmisiano, Neil, Wen, Kuang-Yi, Wilde, Lindsay

“…Cigarette smoking has been associated with increased risk of developing acute myeloid leukemia (AML) in adults. There is limited data on the impact of smoking…”
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Ipilimumab, nivolumab, and brentuximab vedotin combination therapies in patients with relapsed or refractory Hodgkin lymphoma: phase 1 results of an open-label, multicentre, phase 1/2 trial by Diefenbach, Catherine S, Hong, Fangxin, Ambinder, Richard F, Cohen, Jonathon B, Robertson, Michael J, David, Kevin A, Advani, Ranjana H, Fenske, Timothy S, Barta, Stefan K, Palmisiano, Neil D, Svoboda, Jakub, Morgan, David S, Karmali, Reem, Sharon, Elad, Streicher, Howard, Kahl, Brad S, Ansell, Stephen M

“…Recognising that the immune suppressive microenvironment promotes tumour growth in Hodgkin lymphoma, we hypothesised that activating immunity might augment the…”
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KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs by Yan, Fangxue, Li, Jinyang, Milosevic, Jelena, Petroni, Ricardo, Liu, Suying, Shi, Zhennan, Yuan, Salina, Reynaga, Janice M, Qi, Yuwei, Rico, Joshua, Yu, Sixiang, Liu, Yiman, Rokudai, Susumu, Palmisiano, Neil, Meyer, Sara E, Sung, Pamela J, Wan, Liling, Lan, Fei, Garcia, Benjamin A, Stanger, Ben Z, Sykes, David B, Blanco, M Andrés

“…Epigenetic programs are dysregulated in acute myeloid leukemia (AML) and help enforce an oncogenic state of differentiation arrest. To identify key epigenetic…”
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Upfront Treatment of FLT3-Mutated AML: A Look Back at the RATIFY Trial and Beyond by Keiffer, Gina, Aderhold, Kimberly L, Palmisiano, Neil D

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Polo‐like kinase and its inhibitors: Ready for the match to start? by Palmisiano, Neil D., Kasner, Margaret T.

“…Polo‐like kinases (Plks) plays a central role in the normal cell cycle and their upregulation has been shown to play a role in the pathogenesis of multiple…”
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Treating Hematologic Malignancies During a Pandemic: Utilizing Telehealth and Digital Technology to Optimize Care by Binder, Adam F., Handley, Nathan R., Wilde, Lindsay, Palmisiano, Neil, Lopez, Ana Maria

“…In late January 2020, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) was reported as an outbreak in Wuhan, China. Within 2 months it became a…”
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The Role of Inhibition of Apoptosis in Acute Leukemias and Myelodysplastic Syndrome by McBride, Amanda, Houtmann, Sarah, Wilde, Lindsay, Vigil, Carlos, Eischen, Christine M, Kasner, Margaret, Palmisiano, Neil

“…Avoidance of apoptosis is a key mechanism that malignancies, including acute leukemias and MDS, utilize in order to proliferate and resist chemotherapy…”
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Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia by Zhu, Liuluan, Kong, Yaxian, Zhang, Jianhong, Claxton, David F, Ehmann, W Christopher, Rybka, Witold B, Palmisiano, Neil D, Wang, Ming, Jia, Bei, Bayerl, Michael, Schell, Todd D, Hohl, Raymond J, Zeng, Hui, Zheng, Hong

“…T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif (ITIM) domain (TIGIT) and programmed cell death protein 1 (PD-1) are important…”
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Prognostic impact of 'multi-hit' versus 'single hit' TP53 alteration in patients with acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases by Badar, Talha, Nanaa, Ahmad, Atallah, Ehab, Shallis, Rory M, Craver, Emily C, Li, Zhuo, Goldberg, Aaron D, Saliba, Antoine N, Patel, Anand, Bewersdorf, Jan P, Duvall, Adam, Burkart, Madelyn, Bradshaw, Danielle, Abaza, Yasmin, Stahl, Maximilian, Palmisiano, Neil, Murthy, Guru Subramanian Guru, Zeidan, Amer M, Kota, Vamsi, Patnaik, Mrinal M, Litzow, Mark R

“…While there is clear evidence to suggest poorer outcome associated with multi-hit (MH) TP53 mutation compared to single-hit (SH) in lower-risk myelodysplastic…”
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Efficacy of Half-Day Workshops for Internal Medicine Interns in Educating Breaking-Bad-News Discussions by Thomas, Colin, Kurian, Christine, Houtmann, Sarah, Palmisiano, Neil

“…Background: Adequate end-of-life (EOL) care/breaking-bad-news (BBN) discussions with patients are becoming increasingly essential to adequate patient care…”
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A phase 1 trial of venetoclax in combination with liposomal vincristine in patients with relapsed or refractory B‐cell or T‐cell acute lymphoblastic leukemia: Results from the ECOG‐ACRIN EA9152 protocol by Palmisiano, Neil D., Lee, Ju‐Whei, Claxton, David F., Paietta, Elisabeth M., Alkhateeb, Hassan, Park, Jae, Podoltsev, Nikolai A., Atallah, Ehab L., Schaar, Dale G., Dinner, Shira N., Webster, Jonathan A., Luger, Selina M., Litzow, Mark R.

“…Introduction Relapsed or refractory (r/r) acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LL) remains a therapeutic challenge. Preclinical data…”
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Comparing venetoclax in combination with hypomethylating agents to hypomethylating agent-based therapies for treatment naive TP53-mutated acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND) by Badar, Talha, Nanaa, Ahmad, Atallah, Ehab, Shallis, Rory M., Guilherme, Sacchi de Camargo Correia, Goldberg, Aaron D., Saliba, Antoine N., Patel, Anand, Bewersdorf, Jan P., DuVall, Adam S., Bradshaw, Danielle, Abaza, Yasmin, Murthy, Guru Subramanian Guru, Palmisiano, Neil, Zeidan, Amer M., Kota, Vamsi, Litzow, Mark R.

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Correction to: An adapted European LeukemiaNet genetic risk stratification for acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplant. A CIBMTR analysis by Jimenez Jimenez, Antonio M., De Lima, Marcos, Komanduri, Krishna V., Wang, Trent P., Zhang, Mei-Jie, Chen, Karen, Abdel-Azim, Hisham, Abid, Muhammad Bilal, Aljurf, Mahmoud, Alkhateeb, Hassan, Assal, Amer, Bacher, Ulrike, Baron, Frédéric, Battiwalla, Minoo, Beitinjaneh, Amer, Bejanyan, Nelli, Bhatt, Vijaya Raj, Byrne, Michael, Cahn, Jean-Yves, Cairo, Mitchell, Castillo, Paul, Copelan, Edward, DeFilipp, Zachariah, Perez, Miguel Angel Diaz, Elsawy, Mahmoud, Gale, Robert Peter, George, Biju, Grunwald, Michael R., Hildebrandt, Gerhard C., Hogan, William J., Kanakry, Christopher G., Kansagra, Ankit, Kharfan-Dabaja, Mohamed A., Khera, Nandita, Krem, Maxwell M., Lazaryan, Aleksandr, Maakaron, Joseph, Martino, Rodrigo, McGuirk, Joseph, Michelis, Fotios V., Milone, Giuseppe, Mishra, Asmita, Murthy, Hemant S., Mussetti, Alberto, Nathan, Sunita, Nishihori, Taiga, Olsson, Richard F., Palmisiano, Neil, Patel, Sagar, Saad, Ayman, Seo, Sachiko, Sharma, Akshay, Solh, Melhem, Verdonck, Leo F., Wirk, Baldeep, Yared, Jean A., Litzow, Mark, Kebriaei, Partow, Hourigan, Christopher S., Saber, Wael, Weisdorf, Daniel

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Primary central nervous system plasmablastic lymphoma in an HIV-positive patient by Rhoades, Ruben, Gong, Jerald, Palmisiano, Neil, Alpdogan, Onder

“…Plasmablastic lymphoma (PBL) is a rare subtype of diffuse large B-cell lymphoma, highly associated with HIV and Epstein-Barr virus (EBV) infections. It…”
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P489: PROGNOSTIC IMPACT OF “MULTI‐HIT” VERSUS “SINGLE‐HIT” TP53 MUTATION IN PATIENTS WITH ACUTE MYELOID LEUKEMIA: RESULTS FROM THE CONSORTIUM ON MYELOID MALIGNANCIES AND NEOPLASTIC DISEASES (COMMAND) by Badar, Talha, Atallah, Ehab, Shallis, Rory M., D Goldberg, Aaron, Nanaa, Ahmad, Saliba, Antoine, Patel, Anand, Bewersdorf, Jan, Duvall, Adam, Burkart, Madelyn, Bradshaw, Danielle, Abaza, Yasmin, Stahl, Maximillian, Palmisiano, Neil, Subramanian Guru Murthy, Guru, Kota, Vamsi, Zeidan, Amer M., Litzow, Mark

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P354: MULTI‐INSTITUTIONAL STUDY EVALUATING THE IMPACT ON SURVIVAL OF NEWER TREATMENT COMBINATIONS AND ALLOGENEIC STEM CELL TRANSPLANTATION IN PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA by Badar, Talha, Atallah, Ehab, Narra, Ravi, Mims, Alice, Kota, Vamsi, Desai, Shreya, Sacchi de Camargo Correia, Guilherme, Patel, Anand, Duvall, Adam, Palmisiano, Neil, Curran, Emily, Omer, Zulfa, Shallis, Rory M., Advani, Anjali, Litzow, Mark

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T100: Long term Follow‐up of a Phase I Study Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Hodgkin Lymphoma: A trial of the ECOG‐ACRIN Research Group (E4412: Arms A‐I) by Diefenbach, Catherine, Jegede, Opeyemi, Ambinder, Richard, Cohen, Jonathon, Robertson, Michael, David, Kevin, Advani, Ranjana, Fenske, Timothy, Barta, Stefan, Palmisiano, Neil, Svoboda, Jakub, Morgan, David, Karmali, Reem, Kahl, Brad, Ansell, Stephen M.

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