Search Results - "Palmer, Scott M."

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis by Palmer, Scott M., Snyder, Laurie, Todd, Jamie L., Soule, Benjamin, Christian, Rose, Anstrom, Kevin, Luo, Yi, Gagnon, Robert, Rosen, Glenn

“…Idiopathic pulmonary fibrosis (IPF) causes irreversible loss of lung function. The lysophosphatidic acid receptor 1 (LPA1) pathway is implicated in IPF…”
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Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome―A consensus report from the Pulmonary Council of the ISHLT by Glanville, Allan R., Verleden, Geert M., Todd, Jamie L., Benden, Christian, Calabrese, Fiorella, Gottlieb, Jens, Hachem, Ramsey R., Levine, Deborah, Meloni, Federica, Palmer, Scott M., Roman, Antonio, Sato, Masaaki, Singer, Lianne G., Tokman, Sofya, Verleden, Stijn E., von der Thüsen, Jan, Vos, Robin, Snell, Gregory

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Advances in Human Lung Transplantation by Swaminathan, Aparna C, Todd, Jamie L, Palmer, Scott M

“…Lung transplantation improves survival and quality of life in patients with advanced pulmonary disease. Over the past several decades, the volume of lung…”
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An Exome Sequencing Study to Assess the Role of Rare Genetic Variation in Pulmonary Fibrosis by Petrovski, Slavé, Todd, Jamie L, Durheim, Michael T, Wang, Quanli, Chien, Jason W, Kelly, Fran L, Frankel, Courtney, Mebane, Caroline M, Ren, Zhong, Bridgers, Joshua, Urban, Thomas J, Malone, Colin D, Finlen Copeland, Ashley, Brinkley, Christie, Allen, Andrew S, O'Riordan, Thomas, McHutchison, John G, Palmer, Scott M, Goldstein, David B

“…Idiopathic pulmonary fibrosis (IPF) is an increasingly recognized, often fatal lung disease of unknown etiology. The aim of this study was to use whole-exome…”
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LungMAP: The Molecular Atlas of Lung Development Program by Ardini-Poleske, Maryanne E, Clark, Robert F, Ansong, Charles, Carson, James P, Corley, Richard A, Deutsch, Gail H, Hagood, James S, Kaminski, Naftali, Mariani, Thomas J, Potter, Steven S, Pryhuber, Gloria S, Warburton, David, Whitsett, Jeffrey A, Palmer, Scott M, Ambalavanan, Namasivayam

“…The National Heart, Lung, and Blood Institute is funding an effort to create a molecular atlas of the developing lung (LungMAP) to serve as a research resource…”
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Clinical Risk Factors for Primary Graft Dysfunction after Lung Transplantation by DIAMOND, Joshua M, LEE, James C, BHORADE, Sangeeta M, CRESPO, Maria, DEMISSIE, Ejigayehu, SONETT, Joshua, WILLE, Keith, ORENS, Jonathan, SHAH, Ashish S, WEINACKER, Ann, ARCASOY, Selim, SHAH, Pali D, KAWUT, Steven M, WILKES, David S, WARE, Lorraine B, PALMER, Scott M, CHRISTIE, Jason D, SHAH, Rupal J, RUSSELL LOCALIO, A, BELLAMY, Scarlett L, LEDERER, David J, CANTU, Edward, KOHL, Benjamin A, LAMA, Vibha N

“…Primary graft dysfunction (PGD) is the main cause of early morbidity and mortality after lung transplantation. Previous studies have yielded conflicting…”
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Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis by Zhang, David, Povysil, Gundula, Kobeissy, Philippe H, Li, Qi, Wang, Binhan, Amelotte, Mason, Jaouadi, Hager, Newton, Chad A, Maher, Toby M, Molyneaux, Philip L, Noth, Imre, Martinez, Fernando J, Raghu, Ganesh, Todd, Jamie L, Palmer, Scott M, Haefliger, Carolina, Platt, Adam, Petrovski, Slavé, Garcia, Joseph A, Goldstein, David B, Garcia, Christine Kim

“…Genetic studies of idiopathic pulmonary fibrosis (IPF) have improved our understanding of this disease, but not all causal loci have been identified. To…”
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Prognostic implications of and clinical risk factors for acute lung injury and organizing pneumonia after lung transplantation: Data from a multicenter prospective cohort study by Pavlisko, Elizabeth N., Neely, Megan L., Kopetskie, Heather, Hwang, David M., Farver, Carol F., Wallace, W. Dean, Arrossi, Andrea, Illei, Peter, Sever, Michelle L., Kirchner, Jerry, Frankel, Courtney W., Snyder, Laurie D., Martinu, Tereza, Shino, Michael Y., Zaffiri, Lorenzo, Williams, Nikki, Robien, Mark A., Singer, Lianne G., Budev, Marie, Tsuang, Wayne, Shah, Pali D., Reynolds, John M., Weigt, S. Sam, Belperio, John A., Palmer, Scott M., Todd, Jamie L.

“…We determined prognostic implications of acute lung injury (ALI) and organizing pneumonia (OP), including timing relative to transplantation, in a multicenter…”
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Impact of forced vital capacity loss on survival after the onset of chronic lung allograft dysfunction by Todd, Jamie L, Jain, Rahil, Pavlisko, Elizabeth N, Finlen Copeland, C Ashley, Reynolds, John M, Snyder, Laurie D, Palmer, Scott M

“…Emerging evidence suggests a restrictive phenotype of chronic lung allograft dysfunction (CLAD) exists; however, the optimal approach to its diagnosis and…”
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Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease by Xiao, Bin, Wang, Yu, Li, Wei, Baker, Megan, Guo, Jian, Corbet, Kelly, Tsalik, Ephraim L., Li, Qi-Jing, Palmer, Scott M., Woods, Christopher W., Li, Zhiguo, Chao, Nelson J., He, You-Wen

“…Acute graft-versus-host disease (aGVHD) is the leading cause of morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT)…”
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Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry by Todd, Jamie L, Neely, Megan L, Overton, Robert, Durham, Katey, Gulati, Mridu, Huang, Howard, Roman, Jesse, Newby, L Kristin, Flaherty, Kevin R, Vinisko, Richard, Liu, Yi, Roy, Janine, Schmid, Ramona, Strobel, Benjamin, Hesslinger, Christian, Leonard, Thomas B, Noth, Imre, Belperio, John A, Palmer, Scott M

“…Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease for which diagnosis and management remain challenging. Defining the circulating proteome in…”
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Body composition and mortality after adult lung transplantation in the United States by Singer, Jonathan P, Peterson, Eric R, Snyder, Mark E, Katz, Patricia P, Golden, Jeffrey A, D'Ovidio, Frank, Bacchetta, Matthew, Sonett, Joshua R, Kukreja, Jasleen, Shah, Lori, Robbins, Hilary, Van Horn, Kristin, Shah, Rupal J, Diamond, Joshua M, Wickersham, Nancy, Sun, Li, Hays, Steven, Arcasoy, Selim M, Palmer, Scott M, Ware, Lorraine B, Christie, Jason D, Lederer, David J

“…Obesity and underweight are contraindications to lung transplantation based on their associations with mortality in studies performed before implementation of…”
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Circulating matrix metalloproteinases and tissue metalloproteinase inhibitors in patients with idiopathic pulmonary fibrosis in the multicenter IPF-PRO Registry cohort by Todd, Jamie L, Vinisko, Richard, Liu, Yi, Neely, Megan L, Overton, Robert, Flaherty, Kevin R, Noth, Imre, Newby, L Kristin, Lasky, Joseph A, Olman, Mitchell A, Hesslinger, Christian, Leonard, Thomas B, Palmer, Scott M, Belperio, John A

“…Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) play important roles in the turnover of extracellular matrix and in the pathogenesis of…”
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Hyaluronan Contributes to Bronchiolitis Obliterans Syndrome and Stimulates Lung Allograft Rejection through Activation of Innate Immunity by TODD, Jamie L, XINGAN WANG, GELMAN, Andrew E, SUGIMOTO, Seichiro, KENNEDY, Vanessa E, ZHANG, Helen L, PAVLISKO, Elizabeth N, KELLY, Fran L, HOWARD HUANG, KREISEL, Daniel, PALMER, Scott M

“…Although innate immunity is increasingly recognized to contribute to lung allograft rejection, the significance of endogenous innate ligands, such as…”
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Lung function trajectories in patients with idiopathic pulmonary fibrosis by Neely, Megan L, Hellkamp, Anne S, Bender, Shaun, Todd, Jamie L, Liesching, Timothy, Luckhardt, Tracy R, Oldham, Justin M, Raj, Rishi, White, Eric S, Palmer, Scott M

“…Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease characterised by decline in lung function. We…”
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The utility of preoperative six-minute-walk distance in lung transplantation by Castleberry, Anthony W, Englum, Brian R, Snyder, Laurie D, Worni, Mathias, Osho, Asishana A, Gulack, Brian C, Palmer, Scott M, Davis, R Duane, Hartwig, Matthew G

“…The use of 6-minute-walk distance (6MWD) as an indicator of exercise capacity to predict postoperative survival in lung transplantation has not previously been…”
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Cytomegalovirus Pneumonitis Is a Risk for Bronchiolitis Obliterans Syndrome in Lung Transplantation by SNYDER, Laurie D, FINLEN-COPELAND, C. Ashley, JACKSON TURBYFILL, W, HOWELL, David, WILLNER, Daniel A, PALMER, Scott M

“…Cytomegalovirus pneumonitis is one of the most prevalent opportunistic infections after lung transplantation. Early studies reported that cytomegalovirus…”
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Circulating metabolic profile in idiopathic pulmonary fibrosis: data from the IPF-PRO Registry by Summer, Ross, Todd, Jamie L, Neely, Megan L, Lobo, L Jason, Namen, Andrew, Newby, L Kristin, Shafazand, Shirin, Suliman, Sally, Hesslinger, Christian, Keller, Sascha, Leonard, Thomas B, Palmer, Scott M, Ilkayeva, Olga, Muehlbauer, Michael J, Newgard, Christopher B, Roman, Jesse

“…The circulating metabolome, reflecting underlying cellular processes and disease biology, has not been fully characterized in patients with idiopathic…”
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Survival after Bronchiolitis Obliterans Syndrome among Bilateral Lung Transplant Recipients by FINLEN COPELAND, C. Ashley, SNYDER, Laurie D, ZAAS, David W, TURBYFILL, W. Jackson, DAVIS, W. Austin, PALMER, Scott M

“…Despite the importance of bronchiolitis obliterans syndrome (BOS) in lung transplantation, little is known regarding the factors that influence survival after…”
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Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression by Ruan, Peifeng, Todd, Jamie L, Zhao, Hongyu, Liu, Yi, Vinisko, Richard, Soellner, Julia F, Schmid, Ramona, Kaner, Robert J, Luckhardt, Tracy R, Neely, Megan L, Noth, Imre, Porteous, Mary, Raj, Rishi, Safdar, Zeenat, Strek, Mary E, Hesslinger, Christian, Palmer, Scott M, Leonard, Thomas B, Salisbury, Margaret L

“…Idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of extracellular matrix in the pulmonary interstitium and progressive functional…”
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