Search Results - "Palmer, Gene C"

Antianxiety properties of the angiotensin II antagonist, DUP 753, in the rat using the elevated plus-maze by Kaiser, F C, Palmer, G C, Wallace, A V, Carr, R D, Fraser-Rae, L, Hallam, C

“…The angiotensin II receptor antagonist, DUP 753 (Losartan), was compared with diazepam for antianxiety properties in the rat using the elevated plus-maze. Oral…”
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Kainic acid and 4-aminopyridine seizure models in mice: evaluation of efficacy of anti-epileptic agents and calcium antagonists by Cramer, C L, Stagnitto, M L, Knowles, M A, Palmer, G C

“…Seizures may be induced in mice in response to stimulation of subtypes of glutamate receptors by kainic acid or inhibition of certain voltage-dependent…”
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Rat middle cerebral artery occlusion: Correlations between histopathology, T2-weighted magnetic resonance imaging, and behavioral indices by Peeling, James, Corbett, Dale, Del Bigio, Marc R., Hudzik, Thomas J., Campbell, T.Mark, Palmer, Gene C.

“…During attempts to develop the intraluminal suture model of transient middle cerebral artery occlusion (MCAO) in the Sprague Dawley strain of rats, we noticed…”
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Remacemide hydrochloride and ARL 15896AR lack abuse potential: additional differences from other uncompetitive NMDA antagonists by Hudzik, T J, Freedman, L, Palmer, G C

“…This study was designed to determine the possible abuse liability and phencyclidine-like effects of the low-affinity uncompetitive N-methyl-D-aspartate (NMDA)…”
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Acute heat stress model of seizures in weanling rats: Influence of prototypic anti-seizure compounds by Palmer, Gene C, Borrelli, Alfonso R, Hudzik, Thomas J, Sparber, Sheldon

“…The present study tested the therapeutic potential for prototype anti-epilepsy drugs using an animal model of infantile febrile seizures. The model consisted…”
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Efficacy of AR-R15896AR in the rat monofilament model of transient middle cerebral artery occlusion by Bialobok, Paul, Cregan, Edward F., Sydserff, Simon G., Eisman, Mark S., Miller, Jerry A., Cross, Alan J., Simmons, Roy, Gendron, Patricia, McCarthy, Dennis J., Palmer, Gene C.

“…The monofilament technique of transient middle cerebral artery occlusion (MCAO) was used in 3 separate studies to evaluate the efficacy of the low-affinity,…”
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Neurochemical coupled actions of transmitters in the microvasculature of the brain by Palmer, G C

“…The discovery that monoamine nerves end on the central microvessels of the choroid plexus, pia-arachnoid and parenchyma has prompted an intense investigation…”
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Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum by Palmer, G C

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Streptozotocin-induced diabetes produces alterations in adenylate cyclase in rat cerebrum, cerebral microvessels and retina by Palmer, G C, Wilson, G L, Chronister, R B

“…Eight weeks following streptozotocin-induced diabetes mellitus in rats, the sensitivity of adenylate cyclase to dopamine (DA) and norepinephrine (NE) was…”
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T2-Weighted MRI Correlates with Long-Term Histopathology, Neurology Scores, and Skilled Motor Behavior in a Rat Stroke Model by PALMER, GENE C., PEELING, JAMES, CORBETT, DALE, Del BIGIO, MARC R., HUDZIK, THOMAS J.

“…: The intraluminal suture model of transient middle cerebral artery occlusion (MCAO) in the Sprague Dawley strain of rats characteristically results in an…”
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T 2 ‐Weighted MRI Correlates with Long‐Term Histopathology, Neurology Scores, and Skilled Motor Behavior in a Rat Stroke Model by PALMER, GENE C., PEELING, JAMES, CORBETT, DALE, Del BIGIO, MARC R., HUDZIK, THOMAS J.

“…A bstract : The intraluminal suture model of transient middle cerebral artery occlusion (MCAO) in the Sprague Dawley strain of rats characteristically results…”
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Appearance of hormone-sensitive adenylate cyclase in the developing human heart by Palmer, G C, Dail, Jr, W G

“…Highly significant (P smaller than 0.0025) increases in adenylate cyclase activity were seen at all fetal age periods (5-17 weeks) whenever sodium fluoride…”
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Neuroprotection by SLIKKER JR, WILLIAM, JONAS, SARAN, AUER, ROLAND N., PALMER, GENE C., NARAHASHI, TOSHIO, YOUDIM, MOUSSA B.H., MAYNARD, KENNETH I., CARBONE, KATHRYN M., TREMBLY, BRUCE

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Lack of evidence for direct involvement of NMDA receptors or polyamines in blood–brain barrier injury after cerebral ischemia in rats by Preston, Edward, Webster, Jacqueline, Palmer, Gene C.

“…It is hypothesized that after various types of brain injury, blood–brain barrier (BBB) opening and vasogenic edema result from excessive neuronal release of…”
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The Low-Affinity, Use-Dependent NMDA Receptor Antagonist AR-R 15896AR: An Update of Progress in Stroke by PALMER, GENE C., CREGAN, EDWARD F., BIALOBOK, PAUL, SYDSERFF, SIMON G., HUDZIK, THOMAS J., McCARTHY, DENNIS J.

“…Use‐dependent N‐methyl‐d‐aspartate (NMDA) receptor antagonists protect neurons from the lethal consequences of excessive stimulation by excitatory amino acids…”
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Neuroprotection: Past Successes and Future Challenges by SLIKKER, WILLIAM, JONAS, SARAN, AUER, ROLAND N., PALMER, GENE C., NARAHASHI, TOSHIO, YOUDIM, MOUSSA B.H., MAYNARD, KENNETH I., CARBONE, KATHRYN M., TREMBLY, BRUCE

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Low-Affinity NMDA Receptor Antagonists by PALMER, GENE C., MILLER, JERRY A., CREGAN, EDWARD F., GENDRON, PATRICIA, PEELING, JAMES

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Anticonvulsant properties of calcium channel blockers in mice: N-methyl-D-,L-aspartate- and Bay K 8644-induced convulsions are potently blocked by the dihydropyridines by Palmer, G C, Stagnitto, M L, Ray, R K, Knowles, M A, Harvey, R, Garske, G E

“…Ten calcium channel blockers were evaluated in mice after intraperitoneal (i.p.) administration for prevention of seizures induced by various convulsants. The…”
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Low-affinity NMDA receptor antagonists. The neuroprotective potential of ARL 15896AR by Palmer, G C, Miller, J A, Cregan, E F, Gendron, P, Peeling, J

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Neuroprotective properties of the uncompetitive NMDA receptor antagonist remacemide hydrochloride by Palmer, G C, Cregan, E F, Borrelli, A R, Willett, F

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